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Journal of Drug Targeting Volume 13, 2005 - Issue 10
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Research Article

Rectal and vaginal administration of insulin–chitosan formulations: An experimental study in rabbits

Zelihagül Değim Faculty of Pharmacy, Gazi University, Department of Pharmaceutical Technology, 06330-Etiler, Ankara, Turkey
,
Tuncer Değim Faculty of Pharmacy, Gazi University, Department of Pharmaceutical Technology, 06330-Etiler, Ankara, Turkey
,
Füsun Acartürk Faculty of Pharmacy, Gazi University, Department of Pharmaceutical Technology, 06330-Etiler, Ankara, Turkey
,
Deniz Erdoğan Faculty of Medicine, Gazi University, Department of Histology, Ankara, Turkey
,
Candan Özoğul Faculty of Medicine, Gazi University, Department of Histology, Ankara, Turkey
&
Mete Köksal Faculty of Medicine, Gazi University, Department of Histology, Ankara, Turkey
Pages 563-572 | Received 18 Jul 2005, Accepted 24 Oct 2005, Published online: 08 Oct 2008

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İ. Tuncer Değim, Fatmanur Tuğcu-Demiröz, Sibel Tamer-İlbasmış & Füsun Acartürk. (2008) Development of Controlled Release Sildenafil Formulations for Vaginal Administration. Drug Delivery 15:4, pages 259-265.
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Claudio González, Diego Kanevsky, Rubén De Marco, Guillermo Di Girolamo & Silvina Santoro. (2006) Non-invasive routes for insulin administration: current state and perspectives. Expert Opinion on Drug Delivery 3:6, pages 763-770.
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Articles from other publishers (23)

Sandip Karmakar, Manas Bhowmik, Bibek Laha & Sreejan Manna. (2023) Recent advancements on novel approaches of insulin delivery. Medicine in Novel Technology and Devices 19, pages 100253.
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Vaisnevee Sugumar, Kuan Ping Ang, Ahmed F. Alshanon, Gautam Sethi, Phelim Voon Chen Yong, Chung Yeng Looi & Won Fen Wong. (2022) A Comprehensive Review of the Evolution of Insulin Development and Its Delivery Method. Pharmaceutics 14:7, pages 1406.
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Farzaneh Sabbagh, Ida Idayu Muhamad, Razieh Niazmand, Pritam Kumar Dikshit & Beom Soo Kim. (2022) Recent progress in polymeric non-invasive insulin delivery. International Journal of Biological Macromolecules 203, pages 222-243.
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Zahra Mazidi, Sanaz Javanmardi, Seyed Morteza Naghib & Zahra Mohammadpour. (2022) Smart stimuli-responsive implantable drug delivery systems for programmed and on-demand cancer treatment: An overview on the emerging materials. Chemical Engineering Journal 433, pages 134569.
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Mengjie Wang, Chunxin Wang, Shuaikai Ren, Junqian Pan, Yan Wang, Yue Shen, Zhanghua Zeng, Haixin Cui & Xiang Zhao. (2022) Versatile Oral Insulin Delivery Nanosystems: From Materials to Nanostructures. International Journal of Molecular Sciences 23:6, pages 3362.
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José das Neves, Fernando Notario-Pérez & Bruno Sarmento. (2021) Women-specific routes of administration for drugs: A critical overview. Advanced Drug Delivery Reviews 176, pages 113865.
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Ernesto Palma, Nicola Costa, Roberto Molinaro, Marco Francardi, Donatella Paolino, Donato Cosco & Massimo Fresta. (2019) Improvement of the therapeutic treatment of inflammatory bowel diseases following rectal administration of mesalazine-loaded chitosan microparticles vs Asamax®. Carbohydrate Polymers 212, pages 430-438.
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Jacques Desbrieres, Catalina Peptu, Lacramiora Ochiuz, Corina Savin, Marcel Popa & Silvia Vasiliu. 2019. Sustainable Agriculture Reviews 36. Sustainable Agriculture Reviews 36 241 314 .
Jéssica Bassi da Silva, Vitaliy V. Khutoryanskiy, Marcos L. Bruschi & Michael T. Cook. (2017) A mucosa-mimetic material for the mucoadhesion testing of thermogelling semi-solids. International Journal of Pharmaceutics 528:1-2, pages 586-594.
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Priti Girotra & Shailendra Kumar Singh. 2015. Handbook of Polymers for Pharmaceutical Technologies. Handbook of Polymers for Pharmaceutical Technologies 33 60 .
Alicia Rodríguez-Gascón, Ana del Pozo-Rodríguez, Arantxazu Isla & María Angeles Solinís. (2015) Vaginal gene therapy. Advanced Drug Delivery Reviews 92, pages 71-83.
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N. B. Mutlu Ağardan, Z. Değim & Ş. Yilmaz. (2014) Antitumoral and MMP-2 inhibition activity of raloxifene or tamoxifen loaded nanoparticles containing dimethyl-β-cyclodextrin. Journal of Inclusion Phenomena and Macrocyclic Chemistry 80:1-2, pages 31-36.
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Katja Klein, Jamie F.S. Mann, Paul Rogers & Robin J. Shattock. (2014) Polymeric penetration enhancers promote humoral immune responses to mucosal vaccines. Journal of Controlled Release 183, pages 43-50.
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José das Neves, Rita Palmeira-de-Oliveira, Ana Palmeira-de-Oliveira, Francisca Rodrigues & Bruno Sarmento. 2014. Mucoadhesive Materials and Drug Delivery Systems. Mucoadhesive Materials and Drug Delivery Systems 99 132 .
Thundiparambil Azeez Sonia & Chandra P. Sharma. 2014. Oral Delivery of Insulin. Oral Delivery of Insulin 59 112 .
José das Neves. 2014. Mucosal Delivery of Biopharmaceuticals. Mucosal Delivery of Biopharmaceuticals 261 280 .
Fatmanur Tuğcu-Demiröz, Füsun Acartürk & Deniz Erdoğan. (2013) Development of long-acting bioadhesive vaginal gels of oxybutynin: Formulation, in vitro and in vivo evaluations. International Journal of Pharmaceutics 457:1, pages 25-39.
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Füsun Acartürk & Nevin Çelebi. 2011. Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine. Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine 45 64 .
Shayne Cox GadJosé das Neves, Maria Helena Amaral & Maria Fernanda Bahia. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia.
Shayne Cox GadNobuhito Shibata, Yukako Ito & Kanji Takada. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia.
Zandrea Ambrose, Lara Compton, Michael PiatakJr.Jr., Ding Lu, W. Gregory Alvord, Mariusz S. Lubomirski, James E. K. Hildreth, Jeffrey D. Lifson, Christopher J. Miller & Vineet N. KewalRamani. (2008) Incomplete Protection against Simian Immunodeficiency Virus Vaginal Transmission in Rhesus Macaques by a Topical Antiviral Agent Revealed by Repeat Challenges. Journal of Virology 82:13, pages 6591-6599.
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Rajesh Singh, Shailesh Singh & James W. Lillard. (2008) Past, Present, and Future Technologies for Oral Delivery of Therapeutic Proteins. Journal of Pharmaceutical Sciences 97:7, pages 2497-2523.
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J. das Neves & M.F. Bahia. (2006) Gels as vaginal drug delivery systems. International Journal of Pharmaceutics 318:1-2, pages 1-14.
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