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Journal of Drug Targeting Volume 15, 2007 - Issue 2
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Research Article

DNA delivery to the mitochondria sites using mitochondrial leader peptide conjugated polyethylenimine

Minhyung Lee Department of Bioengineering, College of Engineering, Hanyang University, Seoul, 133-791, South Korea
,
Joon Sig Choi Department of Biochemistry, College of Natural Sciences, Chungnam National University, Daejeon, 305-764, South Korea
,
Min Ji Choi Department of Bioengineering, College of Engineering, Hanyang University, Seoul, 133-791, South Korea
,
Youngmi Kim Pak Asan Institute for Life Science, University of Ulsan, Seoul, 138-736, South Korea
,
Byoung Doo Rhee Mitochondrial Research Group, Department of Internal Medicine, College of Medicine, Inje University, Seoul, 139-707, South Korea
&
Kyung Soo Ko Mitochondrial Research Group, Department of Internal Medicine, College of Medicine, Inje University, Seoul, 139-707, South Korea
Pages 115-122 | Received 09 Jun 2006, Accepted 11 Aug 2006, Published online: 08 Oct 2008

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Gerard GM D'Souza & Volkmar Weissig. (2009) Subcellular targeting: a new frontier for drug-loaded pharmaceutical nanocarriers and the concept of the magic bullet. Expert Opinion on Drug Delivery 6:11, pages 1135-1148.
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Minhyung Lee, Joon Sig Choi & Kyung Soo Ko. (2008) Mitochondria targeting delivery of nucleic acids. Expert Opinion on Drug Delivery 5:8, pages 879-887.
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Articles from other publishers (28)

Takashi Nakamura, Yuma Yamada, Yusuke Sato, Ikramy A. Khalil & Hideyoshi Harashima. (2019) Innovative nanotechnologies for enhancing nucleic acids/gene therapy: Controlling intracellular trafficking to targeted biodistribution. Biomaterials 218, pages 119329.
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Hasnaa A. Elfawy & Biswadeep Das. (2019) Crosstalk between mitochondrial dysfunction, oxidative stress, and age related neurodegenerative disease: Etiologies and therapeutic strategies. Life Sciences 218, pages 165-184.
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Frédérique Weber-Lotfi & André Dietrich. 2018. Mitochondrial Biology and Experimental Therapeutics. Mitochondrial Biology and Experimental Therapeutics 565 592 .
Claudia Battistella & Harm-Anton Klok. (2017) Controlling and Monitoring Intracellular Delivery of Anticancer Polymer Nanomedicines. Macromolecular Bioscience 17:10, pages 1700022.
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Yanping Sun, Zhen Yang, Chunxi Wang, Tianzhi Yang, Cuifang Cai, Xiaoyun Zhao, Li Yang & Pingtian Ding. (2017) Exploring the role of peptides in polymer-based gene delivery. Acta Biomaterialia 60, pages 23-37.
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Gerard D’Souza, Paul Nguyen & Volkmar Weissig. 2016. Drug Delivery Across Physiological Barriers. Drug Delivery Across Physiological Barriers 367 389 .
Bhuvaneshwar Vaidya, Samit Shah & Vivek Gupta. 2015. Mitochondria in Liver Disease. Mitochondria in Liver Disease 169 192 .
Mamta Kapoor & Diane J. Burgess. 2015. Targeted Drug Delivery : Concepts and Design. Targeted Drug Delivery : Concepts and Design 271 312 .
Daria Mileshina, Adnan Khan Niazi, Frédérique Weber-Lotfi, José Gualberto & André Dietrich. 2015. Somatic Genome Manipulation. Somatic Genome Manipulation 275 321 .
Kazuaki Kajimoto, Yusuke Sato, Takashi Nakamura, Yuma Yamada & Hideyoshi Harashima. (2014) Multifunctional envelope-type nano device for controlled intracellular trafficking and selective targeting in vivo. Journal of Controlled Release 190, pages 593-606.
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Ryan M. Pearson, Hao-jui Hsu, Jason Bugno & Seungpyo Hong. (2014) Understanding nano-bio interactions to improve nanocarriers for drug delivery. MRS Bulletin 39:3, pages 227-237.
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Yusuke Sato, Takashi Nakamura, Yuma Yamada, Hidetaka Akita & Hideyoshi Harashima. 2014. Nonviral Vectors for Gene Therapy - Lipid- and Polymer-based Gene Transfer. Nonviral Vectors for Gene Therapy - Lipid- and Polymer-based Gene Transfer 139 204 .
Gwang Sig Yu, Jin Han, Kyung Soo Ko & Joon Sig Choi. (2013) Cationic oligopeptide-conjugated mitochondria targeting sequence as a novel carrier system for mitochondria. Macromolecular Research 22:1, pages 42-46.
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Adnan Khan Niazi, Daria Mileshina, Anne Cosset, Romain Val, Frédérique Weber-Lotfi & André Dietrich. (2013) Targeting nucleic acids into mitochondria: Progress and prospects. Mitochondrion 13:5, pages 548-558.
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Jan Gruber, Sheng Fong, Ce-Belle Chen, Sialee Yoong, Giorgia Pastorin, Sebastian Schaffer, Irwin Cheah & Barry Halliwell. (2013) Mitochondria-targeted antioxidants and metabolic modulators as pharmacological interventions to slow ageing. Biotechnology Advances 31:5, pages 563-592.
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Xue-Qing Zhang, Xiaoyang Xu, Nicolas Bertrand, Eric Pridgen, Archana Swami & Omid C. Farokhzad. (2012) Interactions of nanomaterials and biological systems: Implications to personalized nanomedicine. Advanced Drug Delivery Reviews 64:13, pages 1363-1384.
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Nazila Kamaly, Zeyu Xiao, Pedro M. Valencia, Aleksandar F. Radovic-Moreno & Omid C. Farokhzad. (2012) Targeted polymeric therapeutic nanoparticles: design, development and clinical translation. Chemical Society Reviews 41:7, pages 2971.
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K. Rajasekaran, J. W. Cary, C. A. Chlan, J. M. Jaynes & D. Bhatnagar. 2012. Small Wonders: Peptides for Disease Control. Small Wonders: Peptides for Disease Control 295 315 .
Gerard G.M. D'Souza, Mayura A Wagle, Vaibhav Saxena & Anee Shah. (2011) Approaches for targeting mitochondria in cancer therapy. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1807:6, pages 689-696.
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Young-Wook Won, Kwang Suk Lim & Yong-Hee Kim. (2011) Intracellular organelle-targeted non-viral gene delivery systems. Journal of Controlled Release 152:1, pages 99-109.
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Melani Solomon & Gerard G. M. D’Souza. 2011. Intracellular Delivery. Intracellular Delivery 57 72 .
Volkmar Weissig & Gerard G. M. D'Souza. 2010. Organelle-Specific Pharmaceutical Nanotechnology. Organelle-Specific Pharmaceutical Nanotechnology 385 401 .
Gerard G. M. D'Souza & Volkmar Weissig. 2010. Organelle-Specific Pharmaceutical Nanotechnology. Organelle-Specific Pharmaceutical Nanotechnology 1 13 .
Young Geol YoonMichael D KoobYoung Hyun Yoo. (2010) Re-engineering the mitochondrial genomes in mammalian cells. Anatomy & Cell Biology 43:2, pages 97.
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Rafal Smigrodzki & Francisco R. Portell. 2010. The Future of Aging. The Future of Aging 521 541 .
Sun-Woong Kang, Hee-Won Lim, Sang-Woo Seo, Oju Jeon, Minhyung Lee & Byung-Soo Kim. (2008) Nanosphere-mediated delivery of vascular endothelial growth factor gene for therapeutic angiogenesis in mouse ischemic limbs. Biomaterials 29:8, pages 1109-1117.
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Archana Swami, Raj K. Kurupati, Atul Pathak, Y. Singh, P. Kumar & K.C. Gupta. (2007) A unique and highly efficient non-viral DNA/siRNA delivery system based on PEI-bisepoxide nanoparticles. Biochemical and Biophysical Research Communications 362:4, pages 835-841.
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Kyung Soo Ko. (2007) Mitochondrial Gene Therapy. The Journal of Korean Diabetes Association 31:3, pages 187.
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