References
- Abdallah B, Hassan A, Benoist C, Goula D, Behr JP, Demeneix BA. A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: Polyethylenimine. Hum Gene Ther 1996; 7: 1947–1954
- Ballinger SW, Shoffner JM, Hedaya EV, Trounce I, Polak MA, Koontz DA, Wallace DC. Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion. Nat Genet 1992; 1: 11–15
- Ballinger SW, Shoffner JM, Gebhart S, Koontz DA, Wallace DC. Mitochondrial diabetes revisited. Nat Genet 1994; 7: 458–459
- Brown MD, Hosseini S, Steiner I, Wallace DC, Korn-Lubetzki I. Complete mitochondrial DNA sequence analysis in a family with early-onset dystonia and optic atrophy. Mov Disord 2004; 19: 235–237
- Brunner S, Furtbauer E, Sauer T, Kursa M, Wagner E. Overcoming the nuclear barrier: Cell cycle independent nonviral gene transfer with linear polyethylenimine or electroporation. Mol Ther 2002; 5: 80–86
- Cartier R, Reszka R. Utilization of synthetic peptides containing nuclear localization signals for nonviral gene transfer systems. Gene Ther 2002; 9: 157–167
- Chan CK, Jans DA. Enhancement of polylysine-mediated transferrinfection by nuclear localization sequences: Polylysine does not function as a nuclear localization sequence. Hum Gene Ther 1999; 10: 1695–1702
- Chan CK, Senden T, Jans DA. Supramolecular structure and nuclear targeting efficiency determine the enhancement of transfection by modified polylysines. Gene Ther 2000; 7: 1690–1697
- D'Souza GG, Weissig V. Approaches to mitochondrial gene therapy. Curr Gene Ther 2004; 4: 317–328
- D'Souza GG, Rammohan R, Cheng SM, Torchilin VP, Weissig V. DQAsome-mediated delivery of plasmid DNA toward mitochondria in living cells. J Control Release 2003; 92: 189–197
- D'Souza GG, Boddapati SV, Weissig V. Mitochondrial leader sequence-plasmid DNA conjugates delivered into mammalian cells by DQAsomes co-localize with mitochondria. Mitochondrion 2005; 5: 352–358
- Entelis NS, Kolesnikova OA, Martin RP, Tarassov IA. RNA delivery into mitochondria. Adv Drug Deliv Rev 2001; 49: 199–215
- Forrest ML, Pack DW. On the kinetics of polyplex endocytic trafficking: Implications for gene delivery vector design. Mol Ther 2002; 6: 57–66
- Godbey WT, Wu KK, Mikos AG. Poly(ethylenimine) and its role in gene delivery. J Control Release 1999a; 60: 149–160
- Godbey WT, Wu KK, Mikos AG. Size matters: Molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle. J Biomed Mater Res 1999b; 45: 268–275
- Godbey WT, Barry MA, Saggau P, Wu KK, Mikos AG. Poly(ethylenimine)-mediated transfection: A new paradigm for gene delivery. J Biomed Mater Res 2000; 51: 321–328
- Han S, Mahato RI, Sung YK, Kim SW. Development of biomaterials for gene therapy. Mol Ther 2000; 2: 302–317
- Holt IJ, Harding AE, Cooper JM, Schapira AH, Toscano A, Clark JB, Morgan-Hughes JA. Mitochondrial myopathies: Clinical and biochemical features of 30 patients with major deletions of muscle mitochondrial DNA. Ann Neurol 1989; 26: 699–708
- Holt IJ, Harding AE, Petty RK, Morgan-Hughes JA. A new mitochondrial disease associated with mitochondrial DNA heteroplasmy. Am J Hum Genet 1990; 46: 428–433
- Jensen KD, Nori A, Tijerina M, Kopeckova P, Kopecek J. Cytoplasmic delivery and nuclear targeting of synthetic macromolecules. J Control Release 2003; 87: 89–105
- Koh JJ, Ko KS, Lee M, Han S, Park JS, Kim SW. Degradable polymeric carrier for the delivery of IL-10 plasmid DNA to prevent autoimmune insulitis of NOD mice. Gene Ther 2000; 7: 2099–2104
- Lee M, Kim SW. Polymeric gene carriers. Pharm News 2002; 9: 407–415
- Lee M, Kim SW. Polyethylene glycol-conjugated copolymers for plasmid DNA delivery. Pharm Res 2005; 22: 1–10
- Lee M, Han SO, Ko KS, Koh JJ, Park JS, Yoon JW, Kim SW. Repression of GAD autoantigen expression in pancreas beta-cells by delivery of antisense plasmid/PEG-g-PLL complex. Mol Ther 2001; 4: 339–346
- Lee M, Rentz J, Han SO, Bull DA, Kim SW. Water-soluble lipopolymer as an efficient carrier for gene delivery to myocardium. Gene Ther 2003; 10: 585–593
- Lemkine GF, Goula D, Becker N, Paleari L, Levi G, Demeneix BA. Optimisation of polyethylenimine-based gene delivery to mouse brain. J Drug Target 1999; 7: 305–312
- Lill R, Neupert W. Mechanisms of protein import across the mitochondrial outer membrane. Trends Cell Biol 1996; 6: 56–61
- Murphy MP, Smith RA. Drug delivery to mitochondria: The key to mitochondrial medicine. Adv Drug Deliv Rev 2000; 41: 235–250
- Nguyen HK, Lemieux P, Vinogradov SV, Gebhart CL, Guerin N, Paradis G, Bronich TK, Alakhov VY, Kabanov AV. Evaluation of polyether–polyethyleneimine graft copolymers as gene transfer agents. Gene Ther 2000; 7: 126–138
- Nishikawa M, Huang L. Nonviral vectors in the new millennium: Delivery barriers in gene transfer. Hum Gene Ther 2001; 12: 861–870
- Pulkes T, Hanna MG. Human mitochondrial DNA diseases. Adv Drug Deliv Rev 2001; 49: 27–43
- Ruponen M, Honkakoski P, Ronkko S, Pelkonen J, Tammi M, Urtti A. Extracellular and intracellular barriers in non-viral gene delivery. J Control Release 2003; 93: 213–217
- Seibel P, Trappe J, Villani G, Klopstock T, Papa S, Reichmann H. Transfection of mitochondria: Strategy towards a gene therapy of mitochondrial DNA diseases. Nucleic Acids Res 1995; 23: 10–17
- Shoffner JMt, Wallace DC. Oxidative phosphorylation diseases. Disorders of two genomes. Adv Hum Genet 1990; 19: 267–330
- Shoffner JM, Wallace DC. Heart disease and mitochondrial DNA mutations. Heart Dis Stroke 1992; 1: 235–241
- Tang MX, Szoka FC. The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther 1997; 4: 823–832
- Turunen MP, Hiltunen MO, Ruponen M, Virkamaki L, Szoka FC, Jr., Urtti A, Yla-Herttuala S. Efficient adventitial gene delivery to rabbit carotid artery with cationic polymer-plasmid complexes. Gene Ther 1999; 6: 6–11
- Wallace DC. The mitochondrial genome in human adaptive radiation and disease: On the road to therapeutics and performance enhancement. Gene 2005; 354: 169–180
- Wallace DC, Lott MT, Shoffner JM, Brown MD. Diseases resulting from mitochondrial DNA point mutations. J Inherit Metab Dis 1992; 15: 472–479
- Wallace DC, Shoffner JM, Trounce I, Brown MD, Ballinger SW, Corral-Debrinski M, Horton T, Jun AS, Lott MT. Mitochondrial DNA mutations in human degenerative diseases and aging. Biochim Biophys Acta 1995; 1271: 141–151
- Weissig V, Torchilin VP. Cationic bolasomes with delocalized charge centers as mitochondria-specific DNA delivery systems. Adv Drug Deliv Rev 2001; 49: 127–149
- Weissig V, D'Souza GG, Torchilin VP. DQAsome/DNA complexes release DNA upon contact with isolated mouse liver mitochondria. J Control Release 2001; 75: 401–408
- Wiethoff CM, Middaugh CR. Barriers to nonviral gene delivery. J Pharm Sci 2003; 92: 203–217
- Wightman L, Patzelt E, Wagner E, Kircheis R. Development of transferrin-polycation/DNA based vectors for gene delivery to melanoma cells. J Drug Target 1999; 7: 293–303