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Journal of Drug Targeting Volume 25, 2017 - Issue 5
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Original Article

Nebulized anionic guanidinylated O-carboxymethyl chitosan/N-2-hydroxypropyltimehyl ammonium chloride chitosan nanoparticles for siRNA pulmonary delivery: preparation, characterization and in vitro evaluation

Suhui NiDepartment of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaView further author information
,
Yuwen XieDepartment of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaView further author information
,
Yue TangDepartment of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaCorrespondence[email protected]
View further author information
,
Yun LiuDepartment of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaView further author information
,
Jing ChenDepartment of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaView further author information
&
Siyan ZhuDepartment of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaView further author information
Pages 451-462 | Received 04 Nov 2016, Accepted 26 Dec 2016, Published online: 01 Feb 2017

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Rosemol George, Stephanie Hehlgans, Maximillian Fleischmann, Claus Rödel, Emmanouil Fokas & Franz Rödel. (2022) Advances in nanotechnology-based platforms for survivin-targeted drug discovery. Expert Opinion on Drug Discovery 17:7, pages 733-754.
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Articles from other publishers (16)

Liang Dong, Yanan Li, Hailin Cong, Bing Yu & Youqing Shen. (2023) A review of chitosan in gene therapy: Developments and challenges. Carbohydrate Polymers, pages 121562.
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Yun Liu, Salma Ashmawy, Lorenz Latta, Agnes-Valencia Weiss, Alexander F. Kiefer, Sarah Nasr, Brigitta Loretz, Anna K. H. Hirsch, Sangeun Lee & Claus-Michael Lehr. (2023) pH-Responsive Dynaplexes as Potent Apoptosis Inductors by Intracellular Delivery of Survivin siRNA. Biomacromolecules 24:8, pages 3742-3754.
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Chong QiuFei XiaJunzhe ZhangQiaoli ShiYuqing MengChen WangHuanhuan PangLiwei GuChengchao XuQiuyan GuoJigang Wang. (2023) Advanced Strategies for Overcoming Endosomal/Lysosomal Barrier in Nanodrug Delivery. Research 6.
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P. Rachtanapun, C. Rachtanapun, P. Jantrawut, S. Thanakkasaranee, G. Kasi, J. Tantala, P. Panraksa & T. Chaiwarit. 2024. Multifaceted Carboxymethyl Chitosan Derivatives: Properties and Biomedical Applications. Multifaceted Carboxymethyl Chitosan Derivatives: Properties and Biomedical Applications 139 203 .
Marika Grodzicka, Cornelia E. Pena-Gonzalez, Paula Ortega, Sylwia Michlewska, Rebeca Lozano, Maria Bryszewska, Francisco Javier de la Mata & Maksim Ionov. (2022) Heterofunctionalized polyphenolic dendrimers decorated with caffeic acid: Synthesis, characterization and antioxidant activity. Sustainable Materials and Technologies 33, pages e00497.
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Sara A. Valente, Lisete M. Silva, Guido R. Lopes, Bruno Sarmento, Manuel A. Coimbra & Cláudia P. Passos. (2022) Polysaccharide-based formulations as potential carriers for pulmonary delivery – A review of their properties and fates. Carbohydrate Polymers 277, pages 118784.
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Sabya Sachi Das, Sweta Kar, Sandeep Kumar Singh, Afzal Hussain, P.R.P. Verma & Sarwar Beg. 2022. Chitosan in Drug Delivery. Chitosan in Drug Delivery 323 360 .
Yishu Yan, Qingqing Wu, Panpan Ren, Qiuyi Liu, Na Zhang, Yang Ji & Jingxian Liu. (2021) Zinc ions coordinated carboxymethyl chitosan-hyaluronic acid microgel for pulmonary drug delivery. International Journal of Biological Macromolecules 193, pages 1043-1049.
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Małgorzata Kubczak, Sylwia Michlewska, Maria Bryszewska, Achim Aigner & Maksim Ionov. (2021) Nanoparticles for local delivery of siRNA in lung therapy. Advanced Drug Delivery Reviews 179, pages 114038.
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Ramzi Mukred Saeed, Mohammed Abdullah, Mamoun Ahram & Mutasem Omar Taha. (2021) Novel Ellipsoid Chitosan-Phthalate Lecithin Nanoparticles for siRNA Delivery. Frontiers in Bioengineering and Biotechnology 9.
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Nitin Bharat Charbe, Nikhil D. Amnerkar, B. Ramesh, Murtaza M. Tambuwala, Hamid A. Bakshi, Alaa A.A. Aljabali, Saurabh C. Khadse, Rajendran Satheeshkumar, Saurabh Satija, Meenu Metha, Dinesh Kumar Chellappan, Garima Shrivastava, Gaurav Gupta, Poonam Negi, Kamal Dua & Flavia C. Zacconi. (2020) Small interfering RNA for cancer treatment: overcoming hurdles in delivery. Acta Pharmaceutica Sinica B 10:11, pages 2075-2109.
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Uttam Kumar Basak, C Roobala, Jaydeep K Basu & Prabal K Maiti. (2020) Size-dependent interaction of hydrophilic/hydrophobic ligand functionalized cationic and anionic nanoparticles with lipid bilayers. Journal of Physics: Condensed Matter 32:10, pages 104003.
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Yue Tang, Yun Liu, Yuwen Xie, Jing Chen & Yushun Dou. (2020) Apoptosis of A549 cells by small interfering RNA targeting survivin delivery using poly-β-amino ester/guanidinylated O-carboxymethyl chitosan nanoparticles. Asian Journal of Pharmaceutical Sciences 15:1, pages 121-128.
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Hironori Kasai, Kenji Inoue, Kentaro Imamura, Carlo Yuvienco, Jin K. Montclare & Seiichi Yamano. (2019) Efficient siRNA delivery and gene silencing using a lipopolypeptide hybrid vector mediated by a caveolae-mediated and temperature-dependent endocytic pathway. Journal of Nanobiotechnology 17:1.
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Yun Liu, Jing Chen, Yue Tang, Shuhan Li, Yushun Dou & Jiewen Zheng. (2018) Synthesis and Characterization of Quaternized Poly(β-amino ester) for Highly Efficient Delivery of Small Interfering RNA. Molecular Pharmaceutics 15:10, pages 4558-4567.
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Yunna Chen, Li Sun, Dongdong Guo, Ziteng Wu & Weidong Chen. (2017) Co-delivery of hypoxia inducible factor-1α small interfering RNA and 5-fluorouracil to overcome drug resistance in gastric cancer SGC-7901 cells. The Journal of Gene Medicine 19:12, pages e2998.
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