Advanced search
Publication Cover
Journal of Drug Targeting Volume 29, 2021 - Issue 2
Submit an article Journal homepage
1,866
Views
48
CrossRef citations to date
0
Altmetric
Review Articles

Mesoporous silica nanoparticles: synthesis methods and their therapeutic use-recent advances

Mohsen Ghaferia Department of Chemical Engineering, Islamic Azad University, Shahrood Branch, Shahrood, IranORCID Iconhttps://orcid.org/0000-0002-6784-8300
ORCID Icon,
Maedeh Koohi Moftakhari Esfahanib School of Chemistry, Physics and Mechanical Engineering, Science and Engineering Faculty, Molecular Design and Synthesis Discipline, Queensland University of Technology, Brisbane, AustraliaORCID Iconhttps://orcid.org/0000-0003-3826-8611
ORCID Icon,
Aun Razac School of Pharmacy, The University of Queensland, Woolloongabba, AustraliaORCID Iconhttps://orcid.org/0000-0003-4960-000X
ORCID Icon,
Sitah Al Harthic School of Pharmacy, The University of Queensland, Woolloongabba, Australia;d Department of Pharmaceutical Science, College of Pharmacy, Shaqra University, Dawadmi, Saudi ArabiaORCID Iconhttps://orcid.org/0000-0003-0031-5654
ORCID Icon,
Hasan Ebrahimi Shahmabadie Department of Microbiology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, IranCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-5222-3829
ORCID Icon &
Seyed Ebrahim Alavic School of Pharmacy, The University of Queensland, Woolloongabba, AustraliaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-4009-4921
ORCID Icon
Pages 131-154 | Received 14 May 2020, Accepted 11 Aug 2020, Published online: 08 Sep 2020

Citations (48)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Yuanyong Jiao, Xiwei Zhang, Hongyu Yang, Hao Ma & Junjie Zou. (2023) Mesoporous tantalum oxide nanomaterials induced cardiovascular endothelial cell apoptosis via mitochondrial-endoplasmic reticulum stress apoptotic pathway. Drug Delivery 30:1, pages 108-120.
Read now
Yuting Tian, Yue Zhang, Mengjiao Zhang, Xianchun Chen, Lei Lei & Tao Hu. (2022) Antisense vicR-Loaded Dendritic Mesoporous Silica Nanoparticles Regulate the Biofilm Organization and Cariogenicity of Streptococcus mutans. International Journal of Nanomedicine 17, pages 1255-1272.
Read now
Seyedeh Masoomeh Sadat Mirnezami, Amir Heydarinasab, Azim Akbarzadeh & Mehdi Arjmand. (2021) Investigation of characterization and cytotoxic effect of PEGylated nanoliposomal containing Melphalan on ovarian cancer: an in vitro study. Journal of Experimental Nanoscience 16:1, pages 101-115.
Read now

Articles from other publishers (45)

Zhen Gao, Xiaoyong Chen, Chen Wang, Jiajia Song, Jiahui Xu, Xiao Liu, Yu Qian & Huayi Suo. (2024) New strategies and mechanisms for targeting Streptococcus mutans biofilm formation to prevent dental caries: A review. Microbiological Research 278, pages 127526.
Crossref
Luiza Bôlla de Menezes, Pâmela Cristine Ladwig Muraro, Daniel Moro Druzian, Yolice Patricia Moreno Ruiz, André Galembeck, Giovani Pavoski, Denise Crocce Romano Espinosa & William Leonardo da Silva. (2024) Calcium oxide nanoparticles: Biosynthesis, characterization and photocatalytic activity for application in yellow tartrazine dye removal. Journal of Photochemistry and Photobiology A: Chemistry 447, pages 115182.
Crossref
Dhananjay Bhatane, Sharon Rose Pamshong, Santosh Sarnaik, Prabakaran A & Amit Alexander. (2023) Potential applications of mesoporous silica nanoparticles for the treatment of neurological disorders. Journal of Drug Delivery Science and Technology 89, pages 104970.
Crossref
Karolinekersin Enoch, Rakavi C. S & Anbumozhi Angayarkanni Somasundaram. (2023) Improved mechanical properties of Chitosan/PVA hydrogel – A detailed Rheological study. Surfaces and Interfaces 41, pages 103178.
Crossref
N. V. Roik & L. A. Belyakova. (2023) Influence of surface steroid groups on sorption of salts of bile acids by mesoporous organosilicas. Himia, Fizika ta Tehnologia Poverhni 14:3, pages 324-340.
Crossref
Astha Sharma, Ganesh R. Kokil, Yan He, Baboucarr Lowe, Arwa Salam, Tariq A. Altalhi, Qingsong Ye & Tushar Kumeria. (2023) Inorganic/organic combination: Inorganic particles/polymer composites for tissue engineering applications. Bioactive Materials 24, pages 535-550.
Crossref
Ruth Prieto‐Montero, Teresa Arbeloa & Virginia Martínez‐Martínez. (2023) Photosensitizer‐Mesoporous Silica Nanoparticles Combination for Enhanced Photodynamic Therapy † . Photochemistry and Photobiology 99:3, pages 882-900.
Crossref
G. S. Bhagyasree, V. N. Reena, M. Abith, T. C. Sabari Girisun & B. Nithyaja. (2023) Enhanced adsorption and non-linear optical properties of DNA-CTAB functionalized mesoporous silica nanoparticles and their influence on enhancement of photoluminescence of Rhodamine 6G dye. AIP Advances 13:5.
Crossref
P.C.L. Muraro, R.D. Wouters, G. Pavoski, D.C.R. Espinosa, Y.P.M. Ruiz, A. Galembeck, V.C. Rech & W.L. da Silva. (2023) Ag/TiNPS nanocatalyst: biosynthesis, characterization and photocatalytic activity. Journal of Photochemistry and Photobiology A: Chemistry 439, pages 114598.
Crossref
Muhammad Zeeshan Asghar, Khadijah Mohammedsaleh Katubi, Mehboob Hassan, Z.A. Alrowaili, Muhammad Usama Arif, Memoona Qammar, M.S. Al-Buriahi, Muhammad Shahid Mahmood & Mirza Mahmood Baig. (2023) A new Y-Zr/g-C3N4 nanoflakes anchored mesoporous silica composite for efficient environmental remediation applications. Diamond and Related Materials 135, pages 109850.
Crossref
Rout George Kerry, Kshitij RB Singh, Subhasis Mahari, Atala Bihari Jena, Bijayananda Panigrahi, Kahnu Charan Pradhan, Satyanarayan Pal, Bhagaban Kisan, Jagneshwar Dandapat, Jay Singh, Shyam S. Pandey, Ravindra Pratap Singh & Sanatan Majhi. (2023) Bioactive potential of morin loaded mesoporous silica nanoparticles: A nobel and efficient antioxidant, antidiabetic and biocompatible abilities in in-silico, in-vitro, and in-vivo models. OpenNano 10, pages 100126.
Crossref
Jayesh Gupta, Mural Quadros & Munira Momin. (2023) Mesoporous silica nanoparticles: Synthesis and multifaceted functionalization for controlled drug delivery. Journal of Drug Delivery Science and Technology 81, pages 104305.
Crossref
Reza Boshrouyeh, Samar Amari, Mohammad Boshrouyeh Ghandashtani, Seyed Ebrahim Alavi & Hasan Ebrahimi Shahmabadi. (2023) A topical gel nanoformulation of amphotericin B (AmB) for the treatment of cutaneous leishmaniasis (CL). Journal of Sol-Gel Science and Technology 105:3, pages 768-780.
Crossref
Matteo Tollemeto, Zheng Huang, Jørn B. Christensen, Hanne Mørck Nielsen & Stine Rønholt. (2023) Mucoadhesive Dendrons Conjugated to Mesoporous Silica Nanoparticles as a Drug Delivery Approach for Orally Administered Biopharmaceuticals. ACS Applied Materials & Interfaces 15:7, pages 8798-8810.
Crossref
V. M. Kumbhar, V. M. Belekar, S. A. Jadhav & P. S. Patil. (2023) Silica@Titanium Dioxide Core-Shell Material for Environmental Remediation Application. Russian Journal of Physical Chemistry B 17:1, pages 222-233.
Crossref
Ni Dong, Zhenyun Liu, Haisheng He, Yi Lu, Jianping Qi & Wei Wu. (2023) “Hook&Loop” multivalent interactions based on disk-shaped nanoparticles strengthen active targeting. Journal of Controlled Release 354, pages 279-293.
Crossref
Yijun Wu, Zhiqiang Sun, Jinfeng Song, Liufang Mo, Xiaochen Wang, Hanhan Liu & Yunfeng Ma. (2022) Preparation of multifunctional mesoporous SiO 2 nanoparticles and anti-tumor action . Nanotechnology 34:5, pages 055101.
Crossref
Bazla Siddiqui, Asim.ur. Rehman, Ihsan-ul Haq, Amal A. Al-Dossary, Abdelhamid Elaissari & Naveed Ahmed. (2022) Exploiting recent trends for the synthesis and surface functionalization of mesoporous silica nanoparticles towards biomedical applications. International Journal of Pharmaceutics: X 4, pages 100116.
Crossref
Seyed Ebrahim Alavi, Naomi Panah, Franck Page, Max Gholami, Alireza Dastfal, Lavanya A Sharma & Hasan Ebrahimi Shahmabadi. (2022) Hydrogel-based therapeutic coatings for dental implants. European Polymer Journal 181, pages 111652.
Crossref
Heping Lian, Shuang Ma, Duoyi Zhao, Wei Zhao, Yan Cui, Yingqi Hua & Zhiyu Zhang. (2022) Cytokine Therapy Combined with Nanomaterials Participates in Cancer Immunotherapy. Pharmaceutics 14:12, pages 2606.
Crossref
Irene Alexandra Spiridon, Irina Draga Căruntu, Iuliana Spiridon & Radu Brăescu. (2022) Insight into Potential Biomedical Application of Mesoporous Materials. Pharmaceutics 14:11, pages 2382.
Crossref
Seyed Ebrahim Alavi, Aun Raza, Max Gholami, Michael Giles, Rayan Al-Sammak, Ali Ibrahim, Hasan Ebrahimi Shahmabadi & Lavanya A. Sharma. (2022) Advanced Drug Delivery Platforms for the Treatment of Oral Pathogens. Pharmaceutics 14:11, pages 2293.
Crossref
Maedeh Koohi Moftakhari Esfahani, Nazrul Islam, Peter J. Cabot & Emad L. Izake. (2021) Development of Thiabendazole-Loaded Mesoporous Silica Nanoparticles for Cancer Therapy. ACS Biomaterials Science & Engineering 8:10, pages 4153-4162.
Crossref
Fang Wang, Huijuan Duan, Weizhe Xu, Gang Sheng, Zhaogang Sun & Hongqian Chu. (2022) Light-activated nanomaterials for tumor immunotherapy. Frontiers in Chemistry 10.
Crossref
Kawther Khalid Ahmed & Amaraporn Wongrakpanich. (2022) Particles-based medicated wound dressings: a comprehensive review. Therapeutic Delivery 13:10, pages 489-505.
Crossref
Yadong Chai, Yanni Zhou & Motohiro Tagaya. (2022) Rubbing-Assisted Approach for Fabricating Oriented Nanobiomaterials. Micromachines 13:8, pages 1358.
Crossref
Maedeh Koohi Moftakhari Esfahani, Seyed Ebrahim Alavi, Peter J. Cabot, Nazrul Islam & Emad L. Izake. (2022) Application of Mesoporous Silica Nanoparticles in Cancer Therapy and Delivery of Repurposed Anthelmintics for Cancer Therapy. Pharmaceutics 14:8, pages 1579.
Crossref
Simona Campora & Giulio Ghersi. (2022) Recent developments and applications of smart nanoparticles in biomedicine. Nanotechnology Reviews 11:1, pages 2595-2631.
Crossref
Radosław Balwierz, Dawid Bursy, Paweł Biernat, Nataliia Hudz, Mariia Shanaida, Łukasz Krzemiński, Paweł Skóra, Monika Biernat & Wioletta Ochędzan Siodłak. (2022) Nano-Silica Carriers Coated by Chloramphenicol: Synthesis, Characterization, and Grinding Trial as a Way to Improve the Release Profile. Pharmaceuticals 15:6, pages 703.
Crossref
Martin Majerník, Rastislav Jendželovský, Jana Vargová, Zuzana Jendželovská & Peter Fedoročko. (2022) Multifunctional Nanoplatforms as a Novel Effective Approach in Photodynamic Therapy and Chemotherapy, to Overcome Multidrug Resistance in Cancer. Pharmaceutics 14:5, pages 1075.
Crossref
Sitah Alharthi, Zyta M. Ziora, Taskeen Janjua, Amirali Popat & Peter M. Moyle. (2022) Formulation and Biological Evaluation of Mesoporous Silica Nanoparticles Loaded with Combinations of Sortase A Inhibitors and Antimicrobial Peptides. Pharmaceutics 14:5, pages 986.
Crossref
Maedeh Koohi Moftakhari Esfahani, Seyed Ebrahim Alavi, Peter J. Cabot, Nazrul Islam & Emad L. Izake. (2022) β-Lactoglobulin-Modified Mesoporous Silica Nanoparticles: A Promising Carrier for the Targeted Delivery of Fenbendazole into Prostate Cancer Cells. Pharmaceutics 14:4, pages 884.
Crossref
Guofeng Su, Ximing Zhong, Songfa Qiu, Jiajin Fan, Hongjun Zhou & Xinhua Zhou. (2022) Preparation of mesoporous silica-based nanocomposites with synergistically antibacterial performance from nano-metal (oxide) and polydopamine. Nanotechnology 33:15, pages 155702.
Crossref
Olga Bochkova, Alexey Dovjenko, Rustem Zairov, Kirill Kholin, Rinata Biktimirova, Svetlana Fedorenko, Irek Nizameev, Artem Laskin, Alexandra Voloshina, Anna Lyubina, Syumbelya Amerhanova, Amina Daminova, Vladimir Evtugyn, Tatiana Gerasimova & Asiya Mustafina. (2022) Silica-Supported Assemblage of CuII Ions with Carbon Dots for Self-Boosting and Glutathione-Induced ROS Generation. Coatings 12:1, pages 97.
Crossref
Seyed Ebrahim Alavi, Maedeh Koohi Moftakhari Esfahani, Aun Raza, Hossein Adelnia & Hasan Ebrahimi Shahmabadi. (2022) PEG-grafted liposomes for enhanced antibacterial and antibiotic activities: An in vivo study. NanoImpact 25, pages 100384.
Crossref
Sujata Paul, El Bethel Lalthavel Hmar, Hemanta Pathak & Hemanta Kumar Sharma. 2022. Nanocarriers for Drug-Targeting Brain Tumors. Nanocarriers for Drug-Targeting Brain Tumors 145 204 .
Melissa Garcia-Carrasco, Itzel F. Parra-Aguilar, Erick P. Gutiérrez-Grijalva, Angel Licea-Claverie & J. Basilio Heredia. 2022. Food, Medical, and Environmental Applications of Nanomaterials. Food, Medical, and Environmental Applications of Nanomaterials 473 491 .
Hao Li, Xueping Chen, Danqing Shen, Fan Wu, Roser Pleixats & Jianming Pan. (2021) Functionalized silica nanoparticles: classification, synthetic approaches and recent advances in adsorption applications. Nanoscale 13:38, pages 15998-16016.
Crossref
Maedeh Koohi Moftakhari Esfahani, Seyed Ebrahim Alavi, Peter J. Cabot, Nazrul Islam & Emad L. Izake. (2021) PEGylated Mesoporous Silica Nanoparticles (MCM-41): A Promising Carrier for the Targeted Delivery of Fenbendazole into Prostrate Cancer Cells. Pharmaceutics 13:10, pages 1605.
Crossref
Seyed Ebrahim Alavi & Hasan Ebrahimi Shahmabadi. (2021) GLP-1 peptide analogs for targeting pancreatic beta cells. Drug Discovery Today 26:8, pages 1936-1943.
Crossref
Samuel Martinez-Erro, Francisco Navas, Eva Romaní-Cubells, Paloma Fernández-García, Victoria Morales, Raul Sanz & Rafael A. García-Muñoz. (2021) Kidney-Protector Lipidic Cilastatin Derivatives as Structure-Directing Agents for the Synthesis of Mesoporous Silica Nanoparticles for Drug Delivery. International Journal of Molecular Sciences 22:15, pages 7968.
Crossref
Aun Raza, Fekade Bruck Sime, Peter J. Cabot, Jason A. Roberts, James R. Falconer, Tushar Kumeria & Amirali Popat. (2021) Liquid CO 2 Formulated Mesoporous Silica Nanoparticles for pH-Responsive Oral Delivery of Meropenem . ACS Biomaterials Science & Engineering 7:5, pages 1836-1853.
Crossref
Seyed Ebrahim Alavi & Hasan Ebrahimi Shahmabadi. (2021) Anthelmintics for drug repurposing: Opportunities and challenges. Saudi Pharmaceutical Journal 29:5, pages 434-445.
Crossref
Diedie Li, Chengzhi Gao, Meiyan Kuang, Minhao Xu, Ben Wang, Yi Luo, Lesheng Teng & Jing Xie. (2021) Nanoparticles as Drug Delivery Systems of RNAi in Cancer Therapy. Molecules 26:8, pages 2380.
Crossref
Aun Raza, Jared A. Miles, Fekade Bruck Sime, Benjamin P. Ross, Jason A. Roberts, Amirali Popat, Tushar Kumeria & James R. Falconer. (2021) PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery. International Journal of Pharmaceutics 597, pages 120280.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.