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Endothelium
Journal of Endothelial Cell Research
Volume 9, 2002 - Issue 3
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Research Article

Inhibition of NADPH Oxidase Activation in Endothelial Cells by ortho -Methoxy-Substituted Catechols

David K. Johnson Department of Chemistry, State University of New York College at Geneseo, Geneseo, New York, USA
,
Kurt J. Schillinger Department of Chemistry, State University of New York College at Geneseo, Geneseo, New York, USA
,
David M. Kwait Department of Chemistry, State University of New York College at Geneseo, Geneseo, New York, USA
,
Chambers V. Hughes Department of Chemistry, State University of New York College at Geneseo, Geneseo, New York, USA
,
Erin J. McNamara Department of Chemistry, State University of New York College at Geneseo, Geneseo, New York, USA
,
Fauod Ishmael Department of Chemistry, State University of New York College at Geneseo, Geneseo, New York, USA
,
Robert W. O'Donnell Department of Biology, State University of New York College at Geneseo, Geneseo, New York, USA
,
Ming-Mei Chang Department of Biology, State University of New York College at Geneseo, Geneseo, New York, USA
,
Michael G. Hogg Oncology Section, Medical VA Care, Stratton VA Medical Center, Albany, New York, USA
,
Jonathan S. Dordick Oncology Section, Medical VA Care, Stratton VA Medical Center, Albany, New York, USA
,
Lakshmi Santhanam Department of Chemical Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA
,
Linda M. Ziegler Department of Chemistry, State University of New York College at Geneseo, Geneseo, New York, USA
&
James A. Holland Department of Chemistry, State University of New York College at Geneseo, Geneseo, New York, USA
 show all
Pages 191-203 | Published online: 13 Jul 2009

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Shreya R. Savla, Ankit P. Laddha & Yogesh A. Kulkarni. (2021) Pharmacology of apocynin: a natural acetophenone. Drug Metabolism Reviews 53:4, pages 542-562.
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Samira Barangi, A. Wallace Hayes & Gholamreza Karimi. (2018) The more effective treatment of atrial fibrillation applying the natural compounds; as NADPH oxidase and ion channel inhibitors. Critical Reviews in Food Science and Nutrition 58:7, pages 1230-1241.
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Gregory J. Gatto$suffix/text()$suffix/text(), Zhaohui Ao, Michael G. Kearse, Mei Zhou, Cyndi R. Morales, Erin Daniels, Benjamin T. Bradley, Matthew T. Goserud, Krista B. Goodman, Stephen A. Douglas, Mark R. Harpel & Douglas G. Johns. (2013) NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation. Journal of Enzyme Inhibition and Medicinal Chemistry 28:1, pages 95-104.
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Daniela Impellizzeri, Emanuela Mazzon, Rosanna Di Paola, Irene Paterniti, Placido Bramanti & Salvatore Cuzzocrea. (2011) Effect of NADPH-oxidase inhibitors in the experimental model of zymosan-induced shock in mice. Free Radical Research 45:7, pages 820-834.
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Daniela Impellizzeri, Emanuela Mazzon, Emanuela Esposito, Irene Paterniti, Placido Bramanti & Salvatore Cuzzocrea. (2011) Effect of Apocynin, an inhibitor of NADPH oxidase, in the inflammatory process induced by an experimental model of spinal cord injury. Free Radical Research 45:2, pages 221-236.
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Chengxue Qin, Suwan Yap & Owen L Woodman. (2009) Antioxidants in the prevention of myocardial ischemia/reperfusion injury. Expert Review of Clinical Pharmacology 2:6, pages 673-695.
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Jing-mei Dong, Sheng-guo Zhao, Guo-yin Huang & Qing Liu. (2004) NADPH Oxidase-mediated Generation of Reactive Oxygen Species is Critically Required for Survival of Undifferentiated Human Promyelocytic Leukemia Cell Line HL-60. Free Radical Research 38:6, pages 629-637.
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Jung-Ok Lee, Cyril Auger, Dong Hyun Park, Moonkyu Kang, Min-Ho Oak, Kyoung Rak Kim & Valérie B. Schini-Kerth. (2013) An Ethanolic Extract of Lindera obtusiloba Stems, YJP-14, Improves Endothelial Dysfunction, Metabolic Parameters and Physical Performance in Diabetic db/db Mice. PLoS ONE 8:6, pages e65227.
Crossref
Angélica Coyoy, Mauricio Olguín-Albuerne, Patricio Martínez-Briseño & Julio Morán. (2013) Role of reactive oxygen species and NADPH-oxidase in the development of rat cerebellum. Neurochemistry International 62:7, pages 998-1011.
Crossref
Ingrid H. C. H. M. Philippens, Jacqueline A. Wubben, Bente Finsen & Bert A. ‘t Hart. (2013) Oral Treatment with the NADPH Oxidase Antagonist Apocynin Mitigates Clinical and Pathological Features of Parkinsonism in the MPTP marmoset Model. Journal of Neuroimmune Pharmacology 8:3, pages 715-726.
Crossref
Ramazan AltintasAlaadin PolatNigar VardiFatih OguzAli BeyturMustafa SagirAzibe YildizHakan Parlakpinar. (2013) The Protective Effects of Apocynin on Kidney Damage Caused by Renal Ischemia/Reperfusion. Journal of Endourology 27:5, pages 617-624.
Crossref
Maicon Petrônio, Maria Zeraik, Luiz Fonseca & Valdecir Ximenes. (2013) Apocynin: Chemical and Biophysical Properties of a NADPH Oxidase Inhibitor. Molecules 18:3, pages 2821-2839.
Crossref
Sunil Joshi, Ammon B. Peck & Saeed R. Khan. (2013) NADPH Oxidase as a Therapeutic Target for Oxalate Induced Injury in Kidneys. Oxidative Medicine and Cellular Longevity 2013, pages 1-18.
Crossref
Anamitra Ghosh, Arthi Kanthasamy, Joy Joseph, Vellareddy Anantharam, Pallavi Srivastava, Brian P Dranka, Balaraman Kalyanaraman & Anumantha G Kanthasamy. (2012) Anti-inflammatory and neuroprotective effects of an orally active apocynin derivative in pre-clinical models of Parkinson’s disease. Journal of Neuroinflammation 9:1.
Crossref
Kenneth R Houser, David K Johnson & Faoud T Ishmael. (2012) Anti-inflammatory effects of methoxyphenolic compounds on human airway cells. Journal of Inflammation 9:1.
Crossref
María Cecilia Castro, Flavio Francini, Guillermo Schinella, Claudia Inés Caldiz, María Guillermina Zubiría, Juan José Gagliardino & María Laura Massa. (2012) Apocynin administration prevents the changes induced by a fructose-rich diet on rat liver metabolism and the antioxidant system. Clinical Science 123:12, pages 681-692.
Crossref
Yvonne Steffen, Gregory Vuillaume, Katrin Stolle, Karin Roewer, Michael Lietz, Jutta Schueller, Stefan Lebrun & Thomas Wallerath. (2012) Cigarette smoke and LDL cooperate in reducing nitric oxide bioavailability in endothelial cells via effects on both eNOS and NADPH oxidase. Nitric Oxide 27:3, pages 176-184.
Crossref
Chih-Feng Chian, Chi-Huei Chiang, Chu Yuan-Jung, Chiao-Hui Chuang, Shiou-Ling Liu, Jheng Yi-Han, Haibo Zhang & Jay H. Ryu. (2012) Apocynin Attenuates Lipopolysaccharide-Induced Lung Injury in an Isolated and Perfused Rat Lung Model. Shock 38:2, pages 196-202.
Crossref
Paulina Kleniewska, Aleksandra Piechota, Beata Skibska & Anna Gorąca. (2012) The NADPH Oxidase Family and its Inhibitors. Archivum Immunologiae et Therapiae Experimentalis 60:4, pages 277-294.
Crossref
Ana Carolina de Almeida, Maria Marluce dos Santos Vilela, Antonio Condino-Neto & Valdecir F. Ximenes. (2012) The Importance of Myeloperoxidase in Apocynin-Mediated NADPH Oxidase Inhibition. ISRN Inflammation 2012, pages 1-7.
Crossref
So Yong Kim, Keun‐Ai Moon, Hee‐Yeon Jo, Sookyung Jeong, Seung‐Han Seon, Eunyu Jung, You Sook Cho, Eunyoung Chun & Ki‐Young Lee. (2011) Anti‐inflammatory effects of apocynin, an inhibitor of NADPH oxidase, in airway inflammation. Immunology & Cell Biology 90:4, pages 441-448.
Crossref
Youyou Zhao, Junkuan Wang, Olivier Ballevre, Hongliang Luo & Weiguo Zhang. (2011) Antihypertensive effects and mechanisms of chlorogenic acids. Hypertension Research 35:4, pages 370-374.
Crossref
Mauricio Mora-Pale, Seok Joon Kwon, Robert J. Linhardt & Jonathan S. Dordick. (2012) Trimer hydroxylated quinone derived from apocynin targets cysteine residues of p47phox preventing the activation of human vascular NADPH oxidase. Free Radical Biology and Medicine 52:5, pages 962-969.
Crossref
Larissa Pernomian, Mayara Santos Gomes, Carolina Baraldi Araujo Restini, Leandra Naira Zambelli Ramalho, Carlos Renato Tirapelli & Ana Maria de Oliveira. (2012) The role of reactive oxygen species in the modulation of the contraction induced by angiotensin II in carotid artery from diabetic rat. European Journal of Pharmacology 678:1-3, pages 15-25.
Crossref
Stéphanie Dal-Ros, Christian Bronner, Cyril Auger & Valérie B. Schini-Kerth. (2012) Red wine polyphenols improve an established aging-related endothelial dysfunction in the mesenteric artery of middle-aged rats: Role of oxidative stress. Biochemical and Biophysical Research Communications 419:2, pages 381-387.
Crossref
Massimo Antonelli, Marc Bonten, Jean Chastre, Giuseppe Citerio, Giorgio Conti, J. Randall Curtis, Daniel De Backer, Goran Hedenstierna, Michael Joannidis, Duncan Macrae, Jordi Mancebo, Salvatore M. Maggiore, Alexandre Mebazaa, Jean-Charles Preiser, Patricia Rocco, Jean-François Timsit, Jan Wernerman & Haibo Zhang. (2012) Year in review in Intensive Care Medicine 2011: I. Nephrology, epidemiology, nutrition and therapeutics, neurology, ethical and legal issues, experimentals. Intensive Care Medicine 38:2, pages 192-209.
Crossref
Kari A. Trumbull, Donna McAllister, Mandi M. Gandelman, Whitney Y. Fung, Thomas Lew, Lucy Brennan, Nathan Lopez, Jeff Morré, Balaraman Kalyanaraman & Joseph S. Beckman. (2012) Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice. Neurobiology of Disease 45:1, pages 137-144.
Crossref
Akbar Ahmad, Stefania Mondello, Rosanna Di Paola, Emanuela Mazzon, Emanuela Esposito, Maria Antonietta Catania, Domenico Italiano, Patrizia Mondello, Carmela Aloisi & Salvatore Cuzzocrea. (2012) Protective effect of apocynin, a NADPH-oxidase inhibitor, against contrast-induced nephropathy in the diabetic rats: A comparison with n-acetylcysteine. European Journal of Pharmacology 674:2-3, pages 397-406.
Crossref
Wakako TakabeNelson JenLisong AiRyan HamiltonSky WangKristin HolmesFarhad DharbandiBhavraj KhalsaSteven BresslerMark L. BarrRongsong LiTzung K. Hsiai. (2011) Oscillatory Shear Stress Induces Mitochondrial Superoxide Production: Implication of NADPH Oxidase and c-Jun NH 2 -Terminal Kinase Signaling . Antioxidants & Redox Signaling 15:5, pages 1379-1388.
Crossref
Chi-Huei Chiang, Chiao-Hui Chuang, Shiou-Ling Liu, Tzong-Shyuan Lee, Yu Ru Kou & Haibo Zhang. (2011) Apocynin attenuates ventilator-induced lung injury in an isolated and perfused rat lung model. Intensive Care Medicine 37:8, pages 1360-1367.
Crossref
Chi-Huei Chiang, Chiao-Hui Chuang & Shiou-Ling Liu. (2011) Apocynin attenuates ischemia-reperfusion lung injury in an isolated and perfused rat lung model. Translational Research 158:1, pages 17-29.
Crossref
Xiaoyu Lu, Sainan Wan, Jie Jiang, Xiaojian Jiang, Wenjing Yang, Pei Yu, Lipeng Xu, Zaijun Zhang, Gaoxiao Zhang, Luchen Shan & Yuqiang Wang. (2011) Synthesis and biological evaluations of novel apocynin analogues. European Journal of Medicinal Chemistry 46:7, pages 2691-2698.
Crossref
L Pernomian, MS Gomes & AM de Oliveira. (2011) Balloon catheter injury abolishes phenylephrine‐induced relaxation in the rat contralateral carotid. British Journal of Pharmacology 163:4, pages 770-781.
Crossref
R. Di Paola, E. Mazzon, I. Paterniti, D. Impellizzeri, P. Bramanti & S. Cuzzocrea. (2011) Apocynin, a Plant-Derived Drug, Might Be Useful in the Treatment of Myocardial Ischemia Reperfusion Injury in Rat Hearts. European Journal of Inflammation 9:2, pages 157-168.
Crossref
Daniel W. Trott, John W. Seawright, Meredith J. Luttrell & Christopher R. Woodman. (2011) NAD(P)H oxidase-derived reactive oxygen species contribute to age-related impairments of endothelium-dependent dilation in rat soleus feed arteries. Journal of Applied Physiology 110:5, pages 1171-1180.
Crossref
Daniela Impellizzeri, Emanuela Esposito, Emanuela Mazzon, Irene Paterniti, Rosanna Di Paola, Placido Bramanti & Salvatore Cuzzocrea. (2011) Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation. Biochemical Pharmacology 81:5, pages 636-648.
Crossref
Claudia Piccoli, Giovanni Quarato, Annamaria D’Aprile, Eustacchio Montemurno, Rosella Scrima, Maria Ripoli, Monica Gomaraschi, Pietro Cirillo, Domenico Boffoli, Laura Calabresi, Loreto Gesualdo & Nazzareno Capitanio. (2011) Native LDL-induced oxidative stress in human proximal tubular cells: multiple players involved. Journal of Cellular and Molecular Medicine 15:2, pages 375-395.
Crossref
Tiziana Genovese, Emanuela Mazzon, Irene Paterniti, Emanuela Esposito, Placido Bramanti & Salvatore Cuzzocrea. (2011) Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats. Brain Research 1372, pages 92-102.
Crossref
Stéphanie Dal-Ros, Joffrey Zoll, Anne-Laure Lang, Cyril Auger, Nathalie Keller, Christian Bronner, Bernard Geny & Valérie B. Schini-Kerth. (2011) Chronic intake of red wine polyphenols by young rats prevents aging-induced endothelial dysfunction and decline in physical performance: Role of NADPH oxidase. Biochemical and Biophysical Research Communications 404:2, pages 743-749.
Crossref
Toshiro Matsui, Akihiro Kudo, Shinji Tokuda, Kiyoshi Matsumoto & Hirokazu Hosoyama. (2010) Identification of a New Natural Vasorelaxatant Compound, (+)-Osbeckic Acid, from Rutin-free Tartary Buckwheat Extract. Journal of Agricultural and Food Chemistry 58:20, pages 10876-10879.
Crossref
Irene Paterniti, Maria Galuppo, Emanuela Mazzon, Daniela Impellizzeri, Emanuela Esposito, Placido Bramanti & Salvatore Cuzzocrea. (2010) Protective effects of apocynin, an inhibitor of NADPH oxidase activity, in splanchnic artery occlusion and reperfusion. Journal of Leukocyte Biology 88:5, pages 993-1003.
Crossref
Juergen Arnhold & Joerg Flemmig. (2010) Human myeloperoxidase in innate and acquired immunity. Archives of Biochemistry and Biophysics 500:1, pages 92-106.
Crossref
Marília P.P. Kanegae, Antonio Condino-Neto, Luis Alberto Pedroza, Ana Carolina de Almeida, Jussara Rehder, Luiz Marcos da Fonseca & Valdecir F. Ximenes. (2010) Diapocynin versus apocynin as pretranscriptional inhibitors of NADPH oxidase and cytokine production by peripheral blood mononuclear cells. Biochemical and Biophysical Research Communications 393:3, pages 551-554.
Crossref
A.K. Lund. 2010. Comprehensive Toxicology. Comprehensive Toxicology 243 274 .
C. A. Costa, T. A. S. Amaral, L. C. R. M. Carvalho, D. T. Ognibene, A. F. E. da Silva, M. B. Moss, S. S. Valenca, R. S. de Moura & A. C. Resende. (2009) Antioxidant Treatment With Tempol and Apocynin Prevents Endothelial Dysfunction and Development of Renovascular Hypertension. American Journal of Hypertension 22:12, pages 1242-1249.
Crossref
Sergio Papa, Anna Maria Sardanelli, Nazzareno Capitanio & Claudia Piccoli. (2009) Mitochondrial respiratory dysfunction and mutations in mitochondrial DNA in PINK1 familial Parkinsonism. Journal of Bioenergetics and Biomembranes 41:6, pages 509-516.
Crossref
Paul A. Fitzpatrick, Anthony F. Guinan, Tony G. Walsh, Ronan P. Murphy, Maria T. Killeen, Nicholas P. Tobin, Adrian R. Pierotti & Philip M. Cummins. (2009) Down-regulation of neprilysin (EC3.4.24.11) expression in vascular endothelial cells by laminar shear stress involves NADPH oxidase-dependent ROS production. The International Journal of Biochemistry & Cell Biology 41:11, pages 2287-2294.
Crossref
Vincent JaquetLeonardo ScapozzaRobert A. ClarkKarl-Heinz KrauseJ. David Lambeth. (2009) Small-Molecule NOX Inhibitors: ROS-Generating NADPH Oxidases as Therapeutic Targets. Antioxidants & Redox Signaling 11:10, pages 2535-2552.
Crossref
Elisabetta Borchi, Matteo Parri, Laura Papucci, Matteo Becatti, Niccolò Nassi, Paolo Nassi & Chiara Nediani. (2008) Role of NADPH oxidase in H9c2 cardiac muscle cells exposed to simulated ischaemia‐reperfusion. Journal of Cellular and Molecular Medicine 13:8b, pages 2724-2735.
Crossref
Timothy R. Nurkiewicz, Dale W. Porter, Ann F. Hubbs, Samuel Stone, Bean T. Chen, David G. Frazer, Matthew A. Boegehold & Vincent Castranova. (2009) Pulmonary Nanoparticle Exposure Disrupts Systemic Microvascular Nitric Oxide Signaling. Toxicological Sciences 110:1, pages 191-203.
Crossref
Mauricio Mora-Pale, Michel Weïwer, Jingjing Yu, Robert J. Linhardt & Jonathan S. Dordick. (2009) Inhibition of human vascular NADPH oxidase by apocynin derived oligophenols. Bioorganic & Medicinal Chemistry 17:14, pages 5146-5152.
Crossref
Sergio Papa, Vittoria Petruzzella, Salvatore Scacco, Anna Maria Sardanelli, Arcangela Iuso, Damiano Panelli, Rita Vitale, Raffaella Trentadue, Domenico De Rasmo, Nazzareno Capitanio, Claudia Piccoli, Francesco Papa, Michele Scivetti, Enrico Bertini, Teresa Rizza & Giuseppe De Michele. (2009) Pathogenetic mechanisms in hereditary dysfunctions of complex I of the respiratory chain in neurological diseases. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1787:5, pages 502-517.
Crossref
Zequan Yang, Ashish K. Sharma, Melissa Marshall, Irving L. Kron & Victor E. Laubach. (2009) NADPH Oxidase in Bone Marrow–Derived Cells Mediates Pulmonary Ischemia-Reperfusion Injury. American Journal of Respiratory Cell and Molecular Biology 40:3, pages 375-381.
Crossref
Ping Zhang, Mingxiao Hou, Yunfang Li, Xin Xu, Michel Barsoum, YingJie Chen & Robert J. Bache. (2009) NADPH oxidase contributes to coronary endothelial dysfunction in the failing heart. American Journal of Physiology-Heart and Circulatory Physiology 296:3, pages H840-H846.
Crossref
Zequan Yang, Victor E. Laubach, Brent A. French & Irving L. Kron. (2009) Acute hyperglycemia enhances oxidative stress and exacerbates myocardial infarction by activating nicotinamide adenine dinucleotide phosphate oxidase during reperfusion. The Journal of Thoracic and Cardiovascular Surgery 137:3, pages 723-729.
Crossref
Stavros Selemidis, Christopher G. Sobey, Kirstin Wingler, Harald H.H.W. Schmidt & Grant R. Drummond. (2008) NADPH oxidases in the vasculature: Molecular features, roles in disease and pharmacological inhibition. Pharmacology & Therapeutics 120:3, pages 254-291.
Crossref
Claudia Piccoli, Annamaria Sardanelli, Rosella Scrima, Maria Ripoli, Giovanni Quarato, Annamaria D’Aprile, Francesco Bellomo, Salvatore Scacco, Giuseppe De Michele, Alessandro Filla, Arcangela Iuso, Domenico Boffoli, Nazzareno Capitanio & Sergio Papa. (2008) Mitochondrial Respiratory Dysfunction in Familiar Parkinsonism Associated with PINK1 Mutation. Neurochemical Research 33:12, pages 2565-2574.
Crossref
J. David Lambeth, Karl-Heinz Krause & Robert A. Clark. (2008) NOX enzymes as novel targets for drug development. Seminars in Immunopathology 30:3, pages 339-363.
Crossref
Rhian M. Touyz. (2008) Apocynin, NADPH Oxidase, and Vascular Cells. Hypertension 51:2, pages 172-174.
Crossref
Sabine HeumüllerSven WindEduardo Barbosa-SicardHarald H.H.W. SchmidtRudi BusseKatrin SchröderRalf P. Brandes. (2008) Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant. Hypertension 51:2, pages 211-217.
Crossref
J. Stefanska & R. Pawliczak. (2008) Apocynin: Molecular Aptitudes. Mediators of Inflammation 2008, pages 1-10.
Crossref
Yvonne Steffen, Claudia Gruber, Tankred Schewe & Helmut Sies. (2008) Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase. Archives of Biochemistry and Biophysics 469:2, pages 209-219.
Crossref
Amir Sharafkhaneh, Suryakanta Velamuri, Vladimir Badmaev, Charlie Lan & Nicola Hanania. (2016) Review: The potential role of natural agents in treatment of airway inflammation. Therapeutic Advances in Respiratory Disease 1:2, pages 105-120.
Crossref
Marília P.P. Kanegae, Luiz Marcos da Fonseca, Iguatemy L. Brunetti, Sueli de Oliveira Silva & Valdecir F. Ximenes. (2007) The reactivity of ortho-methoxy-substituted catechol radicals with sulfhydryl groups: Contribution for the comprehension of the mechanism of inhibition of NADPH oxidase by apocynin. Biochemical Pharmacology 74:3, pages 457-464.
Crossref
Holly C Williams & Kathy K Griendling. (2007) NADPH Oxidase Inhibitors: New Antihypertensive Agents?. Journal of Cardiovascular Pharmacology 50:1, pages 9-16.
Crossref
Joshua P. Gray, Diane E. Heck, Vladimir Mishin, Peter J.S. Smith, Jun-Yan Hong, Mona Thiruchelvam, Deborah A. Cory-Slechta, Debra L. Laskin & Jeffrey D. Laskin. (2007) Paraquat Increases Cyanide-insensitive Respiration in Murine Lung Epithelial Cells by Activating an NAD(P)H:Paraquat Oxidoreductase. Journal of Biological Chemistry 282:11, pages 7939-7949.
Crossref
Paul K. Witting, Benjamin S. Rayner, Beng-Jing Wu, Natasha A. Ellis & Roland Stocker. (2007) Hydrogen Peroxide Promotes Endothelial Dysfunction by Stimulating Multiple Sources of Superoxide Anion Radical Production and Decreasing Nitric Oxide Bioavailability. Cellular Physiology and Biochemistry 20:5, pages 255-268.
Crossref
Valdecir F. Ximenes, Marília P.P. Kanegae, Sandra R. Rissato & Mário S. Galhiane. (2007) The oxidation of apocynin catalyzed by myeloperoxidase: Proposal for NADPH oxidase inhibition. Archives of Biochemistry and Biophysics 457:2, pages 134-141.
Crossref
Robert F. Klees, Paul C. De Marco, Roman M. Salasznyk, Disha Ahuja, Michael Hogg, Sylvain Antoniotti, Lakshmi Kamath, Jonathan S. Dordick & George E. Plopper. (2006) Apocynin Derivatives Interrupt Intracellular Signaling Resulting in Decreased Migration in Breast Cancer Cells. Journal of Biomedicine and Biotechnology 2006, pages 1-10.
Crossref
Sylvain Antoniotti & Jonathan S. Dordick. (2005) Peroxidase-Catalyzed Coupling of Solid-Supportedortho-Methoxyphenols. Advanced Synthesis & Catalysis 347:7-8, pages 1119-1124.
Crossref
Mamadou Ndiaye, Marta Chataigneau, Irina Lobysheva, Thierry Chataigneau & Valérie B. Schini-Kerth. (2004) Red wine polyphenols‐induced, endothelium‐dependent NO‐mediated relaxation is due to the redox‐sensitive PI3‐kinase/Akt‐dependent phosphorylation of endothelial NO‐synthase in the isolated porcine coronary artery. The FASEB Journal 19:3, pages 1-20.
Crossref
Fiemu E. NwariakuZijuan LiuXudong ZhuDorit NahariChristine IngleRu Feng WuYing GuGeorge SarosiLance S. Terada. (2004) NADPH oxidase mediates vascular endothelial cadherin phosphorylation and endothelial dysfunction. Blood 104:10, pages 3214-3220.
Crossref
Jeffrey M. Dodd-o, Laura E. Welsh, Jorge D. Salazar, Peter L. Walinsky, Eric A. Peck, Jay G. Shake, David J. Caparrelli, Roy C. Ziegelstein, Jay L. Zweier, William A. Baumgartner & David B. Pearse. (2004) Effect of NADPH oxidase inhibition on cardiopulmonary bypass-induced lung injury. American Journal of Physiology-Heart and Circulatory Physiology 287:2, pages H927-H936.
Crossref
Silvia S Barbieri, Viviana Cavalca, Sonia Eligini, Marta Brambilla, Alessia Caiani, Elena Tremoli & Susanna Colli. (2004) Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione redox-dependent mechanisms. Free Radical Biology and Medicine 37:2, pages 156-165.
Crossref
Sylvain Antoniotti, Lakshmi Santhanam, Disha Ahuja, Michael G. Hogg & Jonathan S. Dordick. (2004) Structural Diversity of Peroxidase-Catalyzed Oxidation Products of o -Methoxyphenols . Organic Letters 6:12, pages 1975-1978.
Crossref
M.A Cotter & N.E Cameron. (2003) Effect of the NAD(P)H oxidase inhibitor, apocynin, on peripheral nerve perfusion and function in diabetic rats. Life Sciences 73:14, pages 1813-1824.
Crossref
David G Harrison Hua Cai, Ulf Landmesser & Kathy K Griendling. (2016) The Pickering Lecture British Hypertension Society, 10th September 2002. Journal of the Renin-Angiotensin-Aldosterone System 4:2, pages 51-61.
Crossref
Felice L Bedford. (2021) Removing Fuel from Coronavirus Fire: Blocking Superoxide through NOX Inhibition. SSRN Electronic Journal.
Crossref

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