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Original Articles

SAR Models for Estimating the Percutaneous Absorption of Polynuclear Aromatic Hydrocarbons

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Pages 171-185 | Received 30 Aug 1997, Accepted 12 Feb 1998, Published online: 05 Oct 2006

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Timothy A. Roy, Anthony J. Kriech & Linda V. Osborn. (2020) Percutaneous Absorption of Polycyclic Aromatic Compounds from Fume Condensates of Paving and Built Up Roofing Asphalts. Polycyclic Aromatic Compounds 40:4, pages 945-953.
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Ralph Pirow, Annegret Blume, Nicole Hellwig, Matthias Herzler, Bettina Huhse, Christoph Hutzler, Karla Pfaff, Hermann-Josef Thierse, Tewes Tralau, Bärbel Vieth & Andreas Luch. (2019) Mineral oil in food, cosmetic products, and in products regulated by other legislations. Critical Reviews in Toxicology 49:9, pages 742-789.
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Lorenz R. Rhomberg, David B. Mayfield, Julie E. Goodman, Eric L. Butler, Marc A. Nascarella & Daniel R. Williams. (2015) Quantitative cancer risk assessment for occupational exposures to asphalt fumes during built-up roofing asphalt (BURA) operations. Critical Reviews in Toxicology 45:10, pages 873-918.
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A. Khajeh & H. Modarress. (2014) Linear and nonlinear quantitative structure-property relationship modelling of skin permeability. SAR and QSAR in Environmental Research 25:1, pages 35-50.
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Richard P. Moody, Andrey V. Tytchino, Anna Yip & Sanya Petrovic. (2011) A Novel “By Difference” Method for Assessing Dermal Absorption of Polycyclic Aromatic Hydrocarbons from Soil at Federal Contaminated Sites. Journal of Toxicology and Environmental Health, Part A 74:19, pages 1294-1303.
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TimothyA. Roy, AnthonyJ. Kriech & CarlR. Mackerer. (2007) Percutaneous Absorption of Polycyclic Aromatic Compounds from Bitumen Fume Condensate. Journal of Occupational and Environmental Hygiene 4:sup1, pages 137-143.
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H. Frederick Frasch, Ana M. Barbero, Houda Alachkar & James N. McDougal. (2007) Skin Penetration And Lag Times Of Neat And Aqueous Diethyl Phthalate, 1,2-Dichloroethane And Naphthalene. Cutaneous and Ocular Toxicology 26:2, pages 147-160.
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E. Estrada, E. Uriarte, Y. Gutierrez & H. González. (2003) Quantitative structure-toxicity relationships using TOPS-MODE. 3. Structural factors influencing the permeability of commercial solvents through living human skin. SAR and QSAR in Environmental Research 14:2, pages 145-163.
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J. Devillers. (2000) Nonlinear Modeling of the Percutaneous Absorption of Polycyclic Aromatic Hydrocarbons. Polycyclic Aromatic Compounds 18:2, pages 231-241.
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B.D. Gute, G.D. Grunwald & S.C. Basak. (1999) Prediction of the Deral Penetration of Polycyclic Aromatic Hydrocarbons (PAHs): A hierarchical Qsar Approach. SAR and QSAR in Environmental Research 10:1, pages 1-15.
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Articles from other publishers (20)

Ahmed Alalaiwe, Yin-Ku Lin, Chih-Hung Lin, Pei-Wen Wang, Jie-Yu Lin & Jia-You Fang. (2020) The absorption of polycyclic aromatic hydrocarbons into the skin to elicit cutaneous inflammation: The establishment of structure–permeation and in silico–in vitro–in vivo relationships. Chemosphere 255, pages 126955.
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Laszlo Tarko. (2019) Novel criteria for elimination of the outliers in QSPR studies, when the ‘forward stepwise’ procedure is used. Journal of Mathematical Chemistry 57:7, pages 1770-1796.
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Trevor K Peckham, Jeffry H Shirai, Annette L Bunge, Yvette W Lowney, Michael V Ruby & John C Kissel. (2016) Dermal absorption of benzo[a]pyrene into human skin from soil: Effect of artificial weathering, concentration, and exposure duration. Journal of Exposure Science & Environmental Epidemiology 27:6, pages 610-617.
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Atif Kamal & Riffat Naseem Malik. 2017. Xenobiotics in the Soil Environment. Xenobiotics in the Soil Environment 55 71 .
Darren J. Beriro, Mark R. Cave, Joanna Wragg, Russell Thomas, Gareth Wills & Frank Evans. (2016) A review of the current state of the art of physiologically-based tests for measuring human dermal in vitro bioavailability of polycyclic aromatic hydrocarbons (PAH) in soil. Journal of Hazardous Materials 305, pages 240-259.
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Gary P. Moss, Darren R. Gullick & Simon C. WilkinsonGary P. Moss, Darren R. Gullick & Simon C. Wilkinson. 2015. Predictive Methods in Percutaneous Absorption. Predictive Methods in Percutaneous Absorption 65 89 .
. (2014) Systemic Exposure to PAHs and Benzene in Firefighters Suppressing Controlled Structure Fires. The Annals of Occupational Hygiene.
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Laszlo Tarko. (2014) The effect of the diversity of molecules in sets and similarity of sets on the quality of prediction in QSAR studies. Journal of Mathematical Chemistry 52:3, pages 948-965.
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Brian J. Neely, Sundararajan V. Madihally, Robert L. RobinsonJr.Jr. & Khaled A.M. Gasem. (2009) Nonlinear Quantitative Structure-Property Relationship Modeling of Skin Permeation Coefficient. Journal of Pharmaceutical Sciences 98:11, pages 4069-4084.
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Roberto Todeschini & Viviana Consonni. 2009. Molecular Descriptors for Chemoinformatics. Molecular Descriptors for Chemoinformatics 1 241 .
T Bouwman, MTD Cronin, JGM Bessems & JJM van de Sandt. (2008) Improving the applicability of (Q)SARs for percutaneous penetration in regulatory risk assessment. Human & Experimental Toxicology 27:4, pages 269-276.
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Mark Cronin. 2005. Dermal Absorption Models in Toxicology and Pharmacology. Dermal Absorption Models in Toxicology and Pharmacology 113 134 .
Ana Gallegos Saliner & Xavier Gironés. (2005) Topological quantum similarity measures: applications in QSAR. Journal of Molecular Structure: THEOCHEM 727:1-3, pages 97-106.
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Hans F. Stroo, Timothy A. Roy, Cris B. Liban & Joseph P. Kreitinger. (2009) Dermal bioavailability of benzo[ a ]pyrene on lampblack: Implications for risk assessment . Environmental Toxicology and Chemistry 24:6, pages 1568-1572.
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D. Fitzpatrick, J. Corish & B. Hayes. (2004) Modelling skin permeability in risk assessment––the future. Chemosphere 55:10, pages 1309-1314.
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G.P. Moss, J.C. Dearden, H. Patel & M.T.D. Cronin. (2002) Quantitative structure–permeability relationships (QSPRs) for percutaneous absorption. Toxicology in Vitro 16:3, pages 299-317.
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Xavier Giron�s, David Robert & Ramon Carb�-Dorca. (2001) TGSA: A molecular superposition program based on topo-geometrical considerations. Journal of Computational Chemistry 22:2, pages 255-263.
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Roberto Todeschini & Viviana Consonni. 2000. Handbook of Molecular Descriptors. Handbook of Molecular Descriptors 524 667 .
Ramon Carb�-Dorca. (2000) Stochastic transformation of quantum similarity matrices and their use in quantum QSAR (QQSAR) models. International Journal of Quantum Chemistry 79:3, pages 163-177.
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Timothy A. Roy, Andrew J. Krueger, Barbara B. Taylor, David M. Mauro & Lawrence S. Goldstein. (1998) Studies Estimating the Dermal Bioavailability of Polynuclear Aromatic Hydrocarbons from Manufactured Gas Plant Tar-Contaminated Soils. Environmental Science & Technology 32:20, pages 3113-3117.
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