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Free Radical Research Volume 33, 2000 - Issue 2
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Original Article

Mitogen-activated protein kinase, ERK1/2, is essential for the induction of vascular endothelial growth factor by ionizing radiation mediated by activator protein-1 in human glioblastoma cells

Katsuharu Mori Department of Brain Surgery, Nagasaki University School of Medicine, Nagasaki, 852-8501, Japan
,
Masaharu Tani Department of Biochemistry and Molecular Biology in Disease, Atomic Bomb Disease Institute, Nagasaki University School of Medicine, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan
,
Kensaku Kamata Department of Biochemistry, Kyushu University School of Medicine, Maidashi, Fukuoka, 812-8182, Japan
,
Hideki Kawamura Department of Brain Surgery, Nagasaki University School of Medicine, Nagasaki, 852-8501, Japan
,
Yoshishige Urata Department of Biochemistry and Molecular Biology in Disease, Atomic Bomb Disease Institute, Nagasaki University School of Medicine, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan
,
Shinji Goto Department of Biochemistry, Kyushu University School of Medicine, Maidashi, Fukuoka, 812-8182, Japan
,
Michihiko Kuwano Department of Brain Surgery, Nagasaki University School of Medicine, Nagasaki, 852-8501, Japan
,
Shobu Shibata Department of Biochemistry and Molecular Biology in Disease, Atomic Bomb Disease Institute, Nagasaki University School of Medicine, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan
&
Takahito Kondo Department of Biochemistry, Kyushu University School of Medicine, Maidashi, Fukuoka, 812-8182, JapanCorrespondence[email protected]
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Pages 157-166 | Received 22 Dec 1999, Published online: 07 Jul 2009

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Randy D’Amico, Liang Lei, Benjamin C Kennedy, Julia Sisti, Victoria Ebiana, Celina Crisman, James G Christensen, Orlando Gil, Steven S Rosenfeld, Peter Canoll & Jeffrey N Bruce. (2012) The addition of Sunitinib to radiation delays tumor growth in a murine model of glioblastoma. Neurological Research 34:3, pages 252-261.
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Andreana L Rivera & Christopher E Pelloski. (2010) Diagnostic and prognostic molecular markers in common adult gliomas. Expert Review of Molecular Diagnostics 10:5, pages 637-649.
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Won Hee Lee, William E. Sonntag, Matthew Mitschelen, Han Yan & Yong Woo Lee. (2010) Irradiation induces regionally specific alterations in pro-inflammatory environments in rat brain. International Journal of Radiation Biology 86:2, pages 132-144.
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Eui‐Chul Park , Jong‐Bok Yoon, Jin‐Sil Seong , Kyoung‐Soo Choi, Eung‐Sik Kong, Yun‐Jeong Kim, Young‐Mee Park & Eun‐Mi Park. (2006) Effect of Ionizing Radiation on Rat Tissue: Proteomic and Biochemical Analysis. Preparative Biochemistry & Biotechnology 36:1, pages 19-35.
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S. SzkanderovÁ, M. Port, J. StulÍk, L. HernychovÁ, I. KasalovÁ, D. Van Beuningen & M. Abend. (2003) Comparison of the abundance of 10 radiation‐induced proteins with their differential gene expression in L929 cells. International Journal of Radiation Biology 79:8, pages 623-633.
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Articles from other publishers (21)

Roxane M. Bouten, Erik F. Young, Reed Selwyn, Diego Iacono, W. Bradley Rittase & Regina M. Day. 2021. Tissue Barriers in Disease, Injury and Regeneration. Tissue Barriers in Disease, Injury and Regeneration 43 94 .
Anisha Viswanathan, Aliyu Musa, Akshaya Murugesan, João Vale, Carlos Afonso, Saravanan Konda Mani, Olli Yli-Harja, Nuno Candeias & Meenakshisundaram Kandhavelu. (2019) Battling Glioblastoma: A Novel Tyrosine Kinase Inhibitor with Multi-Dimensional Anti-Tumor Effect. Cells 8:12, pages 1624.
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Prakamya Gupta & Pinaki Dutta. (2018) Landscape of Molecular Events in Pituitary Apoplexy. Frontiers in Endocrinology 9.
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Sylwia Kabacik & Ken Raj. (2017) Ionising radiation increases permeability of endothelium through ADAM10-mediated cleavage of VE-cadherin. Oncotarget 8:47, pages 82049-82063.
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Yaqiong Zhang, Lingyue Gao, Zhihua Cheng, Jiayi Cai, Yixuan Niu, Weihong Meng & Qingchun Zhao. (2016) Kukoamine A Prevents Radiation-Induced Neuroinflammation and Preserves Hippocampal Neurogenesis in Rats by Inhibiting Activation of NF-κB and AP-1. Neurotoxicity Research 31:2, pages 259-268.
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Shaker A. Mousa, Vandhana Muralidharan-Chari & Paul J. Davis. 2017. Anti-Angiogenesis Strategies in Cancer Therapeutics. Anti-Angiogenesis Strategies in Cancer Therapeutics 51 68 .
Navrinder Kaur, Atul Ranjan, Vinod Tiwari, Ritu Aneja & Vibha Tandon. (2012) DMA, a Bisbenzimidazole, Offers Radioprotection by Promoting NFκB Transactivation through NIK/IKK in Human Glioma Cells. PLoS ONE 7:6, pages e39426.
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Andreana L. Rivera, Christopher E. Pelloski, Erik Sulman & Ken Aldape. (2008) Prognostic and Predictive Markers in Glioma and Other Neuroepithelial Tumors. Current Problems in Cancer 32:3, pages 97-123.
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Keping Xie & James Yao. 2008. Regulation of Gene Expression in the Tumor Environment. Regulation of Gene Expression in the Tumor Environment 79 124 .
Hartmut Kuhn, Jana Konrad, Silke Holtz, Aida Salameh, Christian Gessner, Stefan Hammerschmidt & Hubert Wirtz. (2006) Enhanced expression of VEGF following bFGF inhibition in non-small cell lung cancer cell lines. Lung Cancer 54:2, pages 149-153.
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Keping Xie, Daoyan Wei, Qian Shi & Suyun Huang. (2004) Constitutive and inducible expression and regulation of vascular endothelial growth factor. Cytokine & Growth Factor Reviews 15:5, pages 297-324.
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Anastasia Parthymou, Dimitris Kardamakis, Ionnis Pavlopoulos & Evangelia Papadimitriou. (2004) Irradiated C6 glioma cells induce angiogenesisin vivo and activate endothelial cellsin vitro. International Journal of Cancer 110:6, pages 807-814.
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Weiling Zhao, Prabhat C. Goswami & Mike E. C. Robbins. (2004) Radiation-Induced Up-regulation of Mmp2 Involves Increased mRNA Stability, Redox Modulation, and MAPK Activation. Radiation Research 161:4, pages 418-429.
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Sheng-Hong Tseng, Swei-Ming Lin, Jin-Cherng Chen, Yen-Hao Su, Hsin-Yi Huang, Chia-Kang Chen, Po-Yin Lin & Yun Chen. (2004) Resveratrol Suppresses the Angiogenesis and Tumor Growth of Gliomas in Rats. Clinical Cancer Research 10:6, pages 2190-2202.
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H. NARANG & M. KRISHNA. (2004) Mitogen-Activated Protein Kinases: Specificity of Response to Dose of Ionizing Radiation in Liver. Journal of Radiation Research 45:2, pages 213-220.
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Oliver Stoeltzing & Lee M. Ellis. 2004. Molecular Targeting and Signal Transduction. Molecular Targeting and Signal Transduction 33 58 .
Sally A Amundson, Michael Bittner & Albert J FornaceJrJr. (2003) Functional genomics as a window on radiation stress signaling. Oncogene 22:37, pages 5828-5833.
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Jennifer E. Morgan, Jacqueline G. Gross, Charles N. Pagel, Jonathan R. Beauchamp, Ariberto Fassati, Adrian J. Thrasher, James P. Di Santo, Ivan B. Fisher, Xu Shiwen, David J. Abraham & Terence A. Partridge. (2002) Myogenic cell proliferation and generation of a reversible tumorigenic phenotype are triggered by preirradiation of the recipient site. The Journal of Cell Biology 157:4, pages 693-702.
Crossref
Yuxin Liang, Xiao-Yong Li, Edward J. Rebar, Peixiang Li, Yuanyue Zhou, Bingliang Chen, Alan P. Wolffe & Casey C. Case. (2002) Activation of Vascular Endothelial Growth Factor A Transcription in Tumorigenic Glioblastoma Cell Lines by an Enhancer with Cell Type-specific DNase I Accessibility. Journal of Biological Chemistry 277:22, pages 20087-20094.
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Lei Xu, Dai Fukumura & Rakesh K. Jain. (2002) Acidic Extracellular pH Induces Vascular Endothelial Growth Factor (VEGF) in Human Glioblastoma Cells via ERK1/2 MAPK Signaling Pathway. Journal of Biological Chemistry 277:13, pages 11368-11374.
Crossref
Sheila Wiseman, Theo Mulder & Anton Rietveld. (2001) Tea Flavonoids: Bioavailability In Vivo and Effects on Cell Signaling Pathways In Vitro . Antioxidants & Redox Signaling 3:6, pages 1009-1021.
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