63
Views
25
CrossRef citations to date
0
Altmetric
Original Article

Primary hepatocyte apoptosis is unlikely to relate to caspase-3 activity under sustained endogenous oxidative stress

, &
Pages 163-173 | Received 27 Sep 2004, Published online: 07 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

F. Zal, F. Khademi, R. Taheri & Z. Mostafavi-Pour. (2018) Antioxidant ameliorating effects against H2O2-induced cytotoxicity in primary endometrial cells. Toxicology Mechanisms and Methods 28:2, pages 122-129.
Read now
Edward L. LeCluyse, Rafal P. Witek, Melvin E. Andersen & Mark J. Powers. (2012) Organotypic liver culture models: Meeting current challenges in toxicity testing. Critical Reviews in Toxicology 42:6, pages 501-548.
Read now
Bin Qu, Wei Wang, Zhenyi Tan, Di Li, Jun Wan, Jie Sun, Kun Cheng & Hao Luo. (2010) Diethyl (6-amino-9H-purin-9-yl) methylphosphonate induces apoptosis and cell cycle arrest in hepatocellular carcinoma BEL-7402 cells: Role of reactive oxygen species. Free Radical Research 44:8, pages 881-890.
Read now
Yasuhiro Ishihara & Norio Shimamoto. (2007) Critical role of exposure time to endogenous oxidative stress in hepatocyte apoptosis. Redox Report 12:6, pages 275-281.
Read now
Shingo Niimi, Mizuho Harashima, Masashi Hyuga & Teruhide Yamaguchi. (2007) Study of hepatocytes using RNA interference. Journal of Organ Dysfunction 3:3, pages 164-182.
Read now

Articles from other publishers (19)

Fatemeh Khademi, Hamidreza Totonchi, Neda Mohammadi, Razieh Zare & Fatemeh Zal. (2019) Nicotine-Induced Oxidative Stress in Human Primary Endometrial Cells. International Journal of Toxicology 38:3, pages 202-208.
Crossref
Yasuhiro Ishihara, Mayumi Tsuji, Toshihiro Kawamoto & Takeshi Yamazaki. (2016) Involvement of reactive oxygen species derived from mitochondria in neuronal injury elicited by methylmercury. Journal of Clinical Biochemistry and Nutrition 59:3, pages 182-190.
Crossref
Jia-Liu Wei, Lian-Shuang Zhang, Jing-Jing Wang, Fang-Zi Guo, Yan-Bo Li, Xian-Qing Zhou & Zhi-Wei Sun. (2015) Endosulfan inducing blood hypercoagulability and endothelial cells apoptosis via the death receptor pathway in Wistar rats. Toxicology Research 4:5, pages 1282-1288.
Crossref
Norio Shimamoto. (2013) A Pathophysiological Role of Cytochrome P450 Involved in Production of Reactive Oxygen Species活性酸素種生成に関与するシトクロームP450の病態生理学的役割. YAKUGAKU ZASSHI 133:4, pages 435-450.
Crossref
Yasuhiro Ishihara & Norio Shimamoto. (2012) Sulfaphenazole Attenuates Myocardial Cell Apoptosis Accompanied With Cardiac Ischemia^|^ndash;Reperfusion by Suppressing the Expression of BimEL and Noxa. Journal of Pharmacological Sciences 119:3, pages 251-259.
Crossref
Yasuhiro Ishihara, Kohhei Katayama, Manami Sakabe, Mana Kitamura, Mami Aizawa, Minami Takara & Kouichi Itoh. (2011) Antioxidant properties of rare sugar D-allose: Effects on mitochondrial reactive oxygen species production in Neuro2A cells. Journal of Bioscience and Bioengineering 112:6, pages 638-642.
Crossref
Maaike SchutteBridget FoxMarc-Olivier BaradezAlison DevonshireJesus MinguezMaria BokhariStefan PrzyborskiDamian Marshall. (2011) Rat Primary Hepatocytes Show Enhanced Performance and Sensitivity to Acetaminophen During Three-Dimensional Culture on a Polystyrene Scaffold Designed for Routine Use. ASSAY and Drug Development Technologies 9:5, pages 475-486.
Crossref
Yasuhiro Ishihara, Fumiaki Ito & Norio Shimamoto. (2011) Increased expression of c‐Fos by extracellular signal‐regulated kinase activation under sustained oxidative stress elicits BimEL upregulation and hepatocyte apoptosis. The FEBS Journal 278:11, pages 1873-1881.
Crossref
Yasuhiro Ishihara, Kenji Takeuchi, Fumiaki Ito & Norio Shimamoto. (2011) Dual regulation of hepatocyte apoptosis by reactive oxygen species: Increases in transcriptional expression and decreases in proteasomal degradation of BimEL. Journal of Cellular Physiology 226:4, pages 1007-1016.
Crossref
Jan Magdalan, Aleksandra Piotrowska, Agnieszka Gomułkiewicz, Tomasz SozańskiAdam Szeląg & Piotr Dziegięl. (2010) Influence of commonly used clinical antidotes on antioxidant systems in human hepatocyte culture intoxicated with α-amanitin. Human & Experimental Toxicology 30:1, pages 38-43.
Crossref
Firdevs Mor & Ozlem Ozmen. (2010) Effect of vitamin C in reducing the toxicity of endosulfan in liver in rabbits. Experimental and Toxicologic Pathology 62:1, pages 75-80.
Crossref
Tan Boon Toh, Minghui Jessica Chen, Arunmozhiarasi Armugam, Zhao Feng Peng, Qiu-Tian Li, Kandiah Jeyaseelan & Nam Sang Cheung. (2008) Antioxidants: Promising neuroprotection against cardiotoxin-4b-induced cell death which triggers oxidative stress with early calpain activation. Toxicon 51:6, pages 964-973.
Crossref
Bo Yuan, Kunio Ohyama, Toshio Bessho, Noboru Uchide & Hiroo Toyoda. (2008) Imbalance between ROS production and elimination results in apoptosis induction in primary smooth chorion trophoblast cells prepared from human fetal membrane tissues. Life Sciences 82:11-12, pages 623-630.
Crossref
Sevim Ercan, Çiğdem Özer, Murat Taş, Deniz Erdoğan & Aydan Babül. (2007) Effects of leptin on stress-induced changes of caspases in rat gastric mucosa. Journal of Gastroenterology 42:6, pages 461-468.
Crossref
Baha Oral, Mehmet Guney, Hilmi Demirin, Meltem Ozguner, Seren Gülsen Giray, Gulnur Take, Tamer Mungan & Irfan Altuntas. (2006) Endometrial damage and apoptosis in rats induced by dichlorvos and ameliorating effect of antioxidant Vitamins E and C. Reproductive Toxicology 22:4, pages 783-790.
Crossref
Yann Wan Yap, Matthew Whiteman, Boon Huat Bay, Yuhong Li, Fwu-Shan Sheu, Robert Z. Qi, Chee Hong Tan & Nam Sang Cheung. (2006) Hypochlorous acid induces apoptosis of cultured cortical neurons through activation of calpains and rupture of lysosomes. Journal of Neurochemistry 98:5, pages 1597-1609.
Crossref
Yasuhiro Ishihara, Dai Shiba & Norio Shimamoto. (2006) Enhancement of DMNQ-induced hepatocyte toxicity by cytochrome P450 inhibition. Toxicology and Applied Pharmacology 214:2, pages 109-117.
Crossref
Lysiane Richert, Michael J. Liguori, Catherine Abadie, Bruno Heyd, Georges Mantion, Nermin Halkic & Jeffrey F. Waring. (2006) GENE EXPRESSION IN HUMAN HEPATOCYTES IN SUSPENSION AFTER ISOLATION IS SIMILAR TO THE LIVER OF ORIGIN, IS NOT AFFECTED BY HEPATOCYTE COLD STORAGE AND CRYOPRESERVATION, BUT IS STRONGLY CHANGED AFTER HEPATOCYTE PLATING. Drug Metabolism and Disposition 34:5, pages 870-879.
Crossref
Yasuhiro Ishihara & Norio Shimamoto. (2006) Involvement of Endonuclease G in Nucleosomal DNA Fragmentation under Sustained Endogenous Oxidative Stress. Journal of Biological Chemistry 281:10, pages 6726-6733.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.