Advanced search
Publication Cover
Free Radical Research Volume 40, 2006 - Issue 6
Submit an article Journal homepage
58
Views
14
CrossRef citations to date
0
Altmetric
Original

Electron spin resonance and spin trapping technique provide direct evidence that edaravone prevents acute ischemia–reperfusion injury of the liver by limiting free radical-mediated tissue damage

Hiroshi Kono University of Yamanashi, First Department of Surgery, Yamanashi, Japan
,
Courtney G. Woods School of Public Health, University of North Carolina, Department of Environmental Sciences and Engineering, Chapel Hill, NC, USA
,
Akira Maki School of Public Health, University of North Carolina, Department of Environmental Sciences and Engineering, Chapel Hill, NC, USA
,
Henry D. Connor NIEHS, Laboratory of Pharmacology and Chemistry, Research Triangle Park, NC, USA
,
Ronald P. Mason NIEHS, Laboratory of Pharmacology and Chemistry, Research Triangle Park, NC, USA
,
Ivan Rusyn School of Public Health, University of North Carolina, Department of Environmental Sciences and Engineering, Chapel Hill, NC, USACorrespondence[email protected]
&
Hideki Fujii University of Yamanashi, First Department of Surgery, Yamanashi, Japan
 show all
Pages 579-588 | Received 06 Nov 2005, Published online: 07 Jul 2009

Citations (14)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Paul A Lapchak. (2010) A critical assessment of edaravone acute ischemic stroke efficacy trials: is edaravone an effective neuroprotective therapy?. Expert Opinion on Pharmacotherapy 11:10, pages 1753-1763.
Read now

Articles from other publishers (13)

Natascha Leleu-Chavain, Romain Regnault, Hania Ahouari, Raphaël Le Biannic, Mostafa Kouach, Frédérique Klupsch, Romain Magnez, Hervé Vezin, Xavier Thuru, Christian Bailly, Jean-François Goossens & Régis Millet. (2022) Antioxidant Properties and Aldehyde Reactivity of PD-L1 Targeted Aryl-Pyrazolone Anticancer Agents. Molecules 27:10, pages 3316.
Crossref
Paul A. Lapchak. 2018. Cellular and Molecular Approaches to Regeneration and Repair. Cellular and Molecular Approaches to Regeneration and Repair 3 20 .
D. Neil Granger & Peter R. Kvietys. (2015) Reperfusion injury and reactive oxygen species: The evolution of a concept. Redox Biology 6, pages 524-551.
Crossref
Munehito Uchiyama, Kentaro Tojo, Takuya Yazawa, Shuhei Ota, Takahisa Goto & Kiyoyasu Kurahashi. (2015) Edaravone prevents lung injury induced by hepatic ischemia–reperfusion. Journal of Surgical Research 194:2, pages 551-557.
Crossref
Adriana Pérez‐González & Annia Galano. (2013) On the hydroperoxyl radical scavenging activity of two Edaravone derivatives: mechanism and kinetics. Journal of Physical Organic Chemistry 26:3, pages 261-268.
Crossref
Adriana Pérez-González & Annia Galano. (2012) On the • OH and • OOH scavenging activity of 3-methyl-1-pyridin-2-yl-5-pyrazolone: Comparisons with its parent compound, edaravone . International Journal of Quantum Chemistry 112:21, pages 3441-3448.
Crossref
KIYOSHI KIKUCHI, NOBUYUKI TAKESHIGE, NAOKI MIURA, YOKO MORIMOTO, TAKASHI ITO, SALUNYA TANCHAROEN, KEI MIYATA, CHIEMI KIKUCHI, NARUMI IIDA, HISAAKI UCHIKADO, NAOHISA MIYAGI, NAOTO SHIOMI, TERUKAZU KURAMOTO, IKURO MARUYAMA, MOTOHIRO MORIOKA & KO-ICHI KAWAHARA. (2012) Beyond free radical scavenging: Beneficial effects of edaravone (Radicut) in various diseases (Review). Experimental and Therapeutic Medicine 3:1, pages 3-8.
Crossref
Adriana Pérez-GonzálezAnnia Galano. (2011) Ionization Energies, Proton Affinities, and p K a Values of a Large Series of Edaravone Derivatives: Implication for Their Free Radical Scavenging Activity . The Journal of Physical Chemistry B 115:34, pages 10375-10384.
Crossref
Adriana Pérez-GonzálezAnnia Galano. (2010) OH Radical Scavenging Activity of Edaravone: Mechanism and Kinetics. The Journal of Physical Chemistry B 115:5, pages 1306-1314.
Crossref
Yong‐Hui Pan, Yong‐Chen Wang, Li‐Ming Zhang & Shu‐Rong Duan. (2010) Protective effect of edaravone against PrP106‐126–induced PC12 cell death. Journal of Biochemical and Molecular Toxicology 24:4, pages 235-241.
Crossref
Barry Halliwell. (2009) The wanderings of a free radical. Free Radical Biology and Medicine 46:5, pages 531-542.
Crossref
Hideyuki Yoshida, A-Hon Kwon, Masaki Kaibori, Katsushige Tsuji, Kozo Habara, Masanori Yamada, Yasuo Kamiyama, Mikio Nishizawa, Seiji Ito & Tadayoshi Okumura. (2008) Edaravone prevents iNOS expression by inhibiting its promoter transactivation and mRNA stability in cytokine-stimulated hepatocytes. Nitric Oxide 18:2, pages 105-112.
Crossref
Gertz I. Likhtenshtein, Jun Yamauchi, Shin'ichi Nakatsuji, Alex I. Smirnov & Rui Tamura. 2008. Nitroxides. Nitroxides 371 399 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.