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Drug Delivery Volume 13, 2006 - Issue 2
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Research Article

Administration of Optimum Sustained-Insulin Release PLGA Microcapsules to Spontaneous Diabetes-Prone BB/WorTky Rats

M. Takenaga Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan
, PhD.,
Y. Yamaguchi Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan
,
Y. Ogawa Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan
,
A. Kitagawa Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan
,
S. Kawai Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan
,
Y. Mizushima Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan
,
R. Igarashi Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan
,
M. Namae Animal Research Center, Tokyo Medical College, Tokyo, Japan
&
K. Komeda Animal Research Center, Tokyo Medical College, Tokyo, Japan
 show all
Pages 149-157 | Received 10 Feb 2005, Accepted 10 Apr 2005, Published online: 10 Oct 2008

Citations (7)

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C. Presmanes, L. de Miguel, R. Espada, C. Álvarez, E. Morales & J.J. Torrado. (2011) Effect of PLGA hydrophilia on the drug release and the hypoglucemic activity of different insulin-loaded PLGA microspheres. Journal of Microencapsulation 28:8, pages 791-798.
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Pratap C. Naha, V. Kanchan, P. K. Manna & Amulya K. Panda. (2008) Improved bioavailability of orally delivered insulin using Eudragit-L30D coated PLGA microparticles. Journal of Microencapsulation 25:4, pages 248-256.
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Articles from other publishers (5)

Kumar Kulldeep Niloy & Tao L. Lowe. (2023) Injectable systems for long-lasting insulin therapy. Advanced Drug Delivery Reviews 203, pages 115121.
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Rezaul H. Ansary, Mokhlesur M. Rahman, Mohamed B. Awang, Haliza Katas, Hazrina Hadi & Abd Almonen Doolaanea. (2016) Preparation, characterization, and in vitro release studies of insulin-loaded double-walled poly(lactide-co-glycolide) microspheres. Drug Delivery and Translational Research 6:3, pages 308-318.
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Peng Zhai, X.B. Chen & David J. Schreyer. (2015) PLGA/alginate composite microspheres for hydrophilic protein delivery. Materials Science and Engineering: C 56, pages 251-259.
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Yong Han, Qing Zeng, Lingling E, Dongsheng Wang, Huixia He & Hongchen Liu. (2012) Sustained Topical Delivery of Insulin From Fibrin Gel Loaded With Poly(Lactic-Co-Glycolic Acid) Microspheres Improves the Biomechanical Retention of Titanium Implants in Type 1 Diabetic Rats. Journal of Oral and Maxillofacial Surgery 70:10, pages 2299-2308.
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Byung Soo Kim, Jae Min Oh, Hoon Hyun, Kyung Sook Kim, Sang Hyo Lee, Yu Han Kim, Kinam Park, Hai Bang Lee & Moon Suk Kim. (2009) Insulin-Loaded Microcapsules for In Vivo Delivery. Molecular Pharmaceutics 6:2, pages 353-365.
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