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Drug Delivery Volume 15, 2008 - Issue 6
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Research Article

Preparation and Evaluation of Fast Dissolving Ibuprofen-Polyethylene Glycol 6000 Solid Dispersions

Madhuri Newa College of Pharmacy, Yeungnam University, Gyongsan, South Korea
,
Krishna H. Bhandari College of Pharmacy, Yeungnam University, Gyongsan, South Korea
,
Jung-Ae Kim College of Pharmacy, Yeungnam University, Gyongsan, South Korea
,
Bong-Kyu Yoo College of Pharmacy, Yeungnam University, Gyongsan, South Korea
,
Han-Gon Choi College of Pharmacy, Yeungnam University, Gyongsan, South Korea
,
Chul-Soon Yong College of Pharmacy, Yeungnam University, Gyongsan, South Korea
,
Jong-Soo Woo Hanmi Pharmaceutical Company Limited, South Korea
&
Won-Seok Lyoo School of Textiles, Yeungnam University, Gyongsan, South Korea
 show all
Pages 355-364 | Received 07 May 2007, Accepted 04 Oct 2007, Published online: 10 Oct 2008

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Ghada E. Yassin & Maha K. A. Khalifa. (2022) Development of eplerenone nano sono-crystals using factorial design: enhanced solubility and dissolution rate via anti solvent crystallization technique. Drug Development and Industrial Pharmacy 48:12, pages 683-693.
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Niloufar Keikhosravi, Seyedeh Zahra Mirdamadian, Jaleh Varshosaz & Azade Taheri. (2020) Preparation and characterization of polypills containing aspirin and simvastatin using 3D printing technology for the prevention of cardiovascular diseases. Drug Development and Industrial Pharmacy 46:10, pages 1665-1675.
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Jagdeep Singh, Tarun Garg, Goutam Rath & Amit K. Goyal. (2016) Advances in nanotechnology-based carrier systems for targeted delivery of bioactive drug molecules with special emphasis on immunotherapy in drug resistant tuberculosis – a critical review. Drug Delivery 23:5, pages 1676-1698.
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Parinda Srinarong, Hans de Waard, Henderik W Frijlink & Wouter LJ Hinrichs. (2011) Improved dissolution behavior of lipophilic drugs by solid dispersions: the production process as starting point for formulation considerations. Expert Opinion on Drug Delivery 8:9, pages 1121-1140.
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Phuong Ha-Lien Tran, Thao Truong-Dinh Tran, Kyoung-Ho Lee, Dong-Jin Kim & Beom-Jin Lee. (2010) Dissolution-modulating mechanism of pH modifiers in solid dispersion containing weakly acidic or basic drugs with poor water solubility. Expert Opinion on Drug Delivery 7:5, pages 647-661.
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Nontsikelelo Noxolo Tafu & Victoria A. Jideani. (2022) Proximate, Elemental, and Functional Properties of Novel Solid Dispersions of Moringa oleifera Leaf Powder. Molecules 27:15, pages 4935.
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Zahra Al-Sahaf, Bahijja Raimi-Abraham, Mariano Licciardi & Laura Modica de Mohac. (2020) Influence of Polyvinyl Alcohol (PVA) on PVA-Poly-N-hydroxyethyl-aspartamide (PVA-PHEA) Microcrystalline Solid Dispersion Films. AAPS PharmSciTech 21:7.
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Kaushalendra Chaturvedi, Harsh S. Shah, Kajal Nahar, Rutesh Dave & Kenneth R. Morris. (2020) Contribution of Crystal Lattice Energy on the Dissolution Behavior of Eutectic Solid Dispersions. ACS Omega 5:17, pages 9690-9701.
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Mohd Aftab Alam, Raishuddin Ali, Fahad Ibrahim Al-Jenoobi & Abdullah M. Al-Mohizea. (2019) The Effect of Carrier Matrix and the Method of Preparing Solid Dispersion on Physical State and Solubility of Ibuprofen. Drug Delivery Letters 9:2, pages 157-165.
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Krishnamoorthy Venkateskumar, Subramani Parasuraman, Raju Gunasunderi, Krishnan Sureshkumar, M. Muralidhar Nayak, Syed Adnan Ali Shah, Khassen Khoo & Heng Wei Kai. (2016) Acyclovir-Polyethylene Glycol 6000 Binary Dispersions: Mechanistic Insights. AAPS PharmSciTech 18:6, pages 2085-2094.
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Davide Germano, Marianne Uteng, Francois Pognan, Salah-Dine Chibout & Armin Wolf. (2015) Determination of liver specific toxicities in rat hepatocytes by high content imaging during 2-week multiple treatment. Toxicology in Vitro 30:1, pages 79-94.
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Kayleen T. Campbell, Duncan Q. M. Craig & Tony McNally. (2014) Modification of ibuprofen drug release from poly(ethylene glycol) layered silicate nanocomposites prepared by hot-melt extrusion. Journal of Applied Polymer Science 131:10, pages n/a-n/a.
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Tin Wui Wong & Nafisah Musa. (2012) Centrifugal air-assisted melt agglomeration for fast-release “granulet” design. International Journal of Pharmaceutics 430:1-2, pages 184-196.
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M. Delwar Hussain, Vipin Saxena, James F. Brausch & Rahmat M. Talukder. (2012) Ibuprofen–phospholipid solid dispersions: Improved dissolution and gastric tolerance. International Journal of Pharmaceutics 422:1-2, pages 290-294.
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Y. Lang, D. P. Finn, A. Pandit & P. J. Walsh. (2011) Pharmacological activity of ibuprofen released from mesoporous silica. Journal of Materials Science: Materials in Medicine 23:1, pages 73-80.
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Maya Davidovich-Pinhas & Havazelet Bianco-Peled. (2010) Novel mucoadhesive system based on sulfhydryl-acrylate interactions. Journal of Materials Science: Materials in Medicine 21:7, pages 2027-2034.
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