1,507
Views
22
CrossRef citations to date
0
Altmetric
Research Article

A novel core-shell lipid nanoparticle for improving oral administration of water soluble chemotherapeutic agents: inhibited intestinal hydrolysis and enhanced lymphatic absorption

, , , , , & show all
Pages 1565-1573 | Received 27 Jul 2017, Accepted 27 Sep 2017, Published online: 13 Oct 2017

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Xinran Wang, Cai Zhang, Ning Han, Juyuan Luo, Shuofeng Zhang, Chunguo Wang, Zhanhong Jia & Shouying Du. (2021) Triglyceride-mimetic prodrugs of scutellarin enhance oral bioavailability by promoting intestinal lymphatic transport and avoiding first-pass metabolism. Drug Delivery 28:1, pages 1664-1672.
Read now
Xue-Jie Qi, Xiang-Yun Liu, Lei-Meng-Yuan Tang, Pan-Feng Li, Feng Qiu & Ai-Hong Yang. (2020) Anti-depressant effect of curcumin-loaded guanidine-chitosan thermo-sensitive hydrogel by nasal delivery. Pharmaceutical Development and Technology 25:3, pages 316-325.
Read now
Pinggang Ding, Yuxuan Chen, Guangshang Cao, Hongxue Shen, Jianming Ju & Weiguang Li. (2019) Solutol®HS15+pluronicF127 and Solutol®HS15+pluronicL61 mixed micelle systems for oral delivery of genistein. Drug Design, Development and Therapy 13, pages 1947-1956.
Read now
Renuka Suresh Managuli, Sushil Yadaorao Raut, Meka Sreenivasa Reddy & Srinivas Mutalik. (2018) Targeting the intestinal lymphatic system: a versatile path for enhanced oral bioavailability of drugs. Expert Opinion on Drug Delivery 15:8, pages 787-804.
Read now

Articles from other publishers (17)

Ting Xiong, Tao Guo, Yaping He, Zeying Cao, Huipeng Xu, Wenting Wu, Li Wu, Weifeng Zhu & Jiwen Zhang. (2022) Lactone Stabilized by Crosslinked Cyclodextrin Metal-Organic Frameworks to Improve Local Bioavailability of Topotecan in Lung Cancer. Pharmaceutics 15:1, pages 142.
Crossref
Andreia Almeida, Flávia Castro, Carlos Resende, Marlene Lúcio, Simó SchwartzJrJr & Bruno Sarmento. (2022) Oral delivery of camptothecin-loaded multifunctional chitosan-based micelles is effective in reduce colorectal cancer. Journal of Controlled Release 349, pages 731-743.
Crossref
Chen Guo, Xichun Zhu, Haoyang Yuan, Haoyu Liu, Yu Zhang, Tian Yin, Haibing He, Jingxin Gou & Xing Tang. (2022) Chitosan-Coated Liposomes: The Strategy to Reduce Intestinal Toxicity and Improve Bioavailability of Oral Vinorelbine. AAPS PharmSciTech 23:5.
Crossref
Rong Lu, Yun Zhou, Jinqian Ma, Yuchen Wang & Xiaoqing Miao. (2022) Strategies and Mechanism in Reversing Intestinal Drug Efflux in Oral Drug Delivery. Pharmaceutics 14:6, pages 1131.
Crossref
Pavel Ryšánek, Tomáš Grus, Peter Lukáč, Petr Kozlík, Tomáš Křížek, Jiří Pozniak, Jaroslava Roušarová, Jana Královičová, Nikolina Kutinová Canová, Tereza Boleslavská, Jan Bosák, František Štěpánek, Martin Šíma & Ondřej Slanař. (2021) Validity of cycloheximide chylomicron flow blocking method for the evaluation of lymphatic transport of drugs. British Journal of Pharmacology 178:23, pages 4663-4674.
Crossref
Muhammad Suhaeri, Young-Min Kim, Rika Tri Yunarti & Soo-Chang Song. (2021) Thermoresponsive and suspension forming cyclotriphosphazene conjugate for delivery vehicle of antitumor drug camptothecin. Journal of Drug Delivery Science and Technology 64, pages 102049.
Crossref
Seung-Hyun Jeong, Ji-Hun Jang & Yong-Bok Lee. (2021) Oral delivery of topotecan in polymeric nanoparticles: Lymphatic distribution and pharmacokinetics. Journal of Controlled Release 335, pages 86-102.
Crossref
S.G. Antimisiaris, A. Marazioti, M. Kannavou, E. Natsaridis, F. Gkartziou, G. Kogkos & S. Mourtas. (2021) Overcoming barriers by local drug delivery with liposomes. Advanced Drug Delivery Reviews 174, pages 53-86.
Crossref
Manjot S. Punjabi, Anup Naha, Disha Shetty & Usha Y. Nayak. (2021) Lymphatic Drug Transport and Associated Drug Delivery Technologies: A Comprehensive Review. Current Pharmaceutical Design 27:17, pages 1992-1998.
Crossref
Sandra Elisa Haas, Tamara Ramos Maciel & Marcelo Gomes de Gomes. 2021. Applications of Nanobiotechnology for Neglected Tropical Diseases. Applications of Nanobiotechnology for Neglected Tropical Diseases 243 252 .
Tao Wang, Liao Shen, Yadan Zhang, Haiyan Li, Yongan Wang & Dongqin Quan. (2020) “Oil-soluble” reversed lipid nanoparticles for oral insulin delivery. Journal of Nanobiotechnology 18:1.
Crossref
Shashank Chaturvedi, Anuj Garg & Anurag Verma. (2020) Nano lipid based carriers for lymphatic voyage of anti-cancer drugs: An insight into the in-vitro, ex-vivo, in-situ and in-vivo study models. Journal of Drug Delivery Science and Technology 59, pages 101899.
Crossref
Pavel Ryšánek, Tomáš Grus, Martin Šíma & Ondřej Slanař. (2020) Lymphatic Transport of Drugs after Intestinal Absorption: Impact of Drug Formulation and Physicochemical Properties. Pharmaceutical Research 37:9.
Crossref
Yadan Zhang, Liao Shen, Tao Wang, Haiyan Li, Ri Huang, Zhen Zhang, Yongan Wang & Dongqin Quan. (2020) Taste masking of water-soluble drug by solid lipid microspheres: a child-friendly system established by reversed lipid-based nanoparticle technique. Journal of Pharmacy and Pharmacology 72:6, pages 776-786.
Crossref
Shuwen Cao, Xiaodi Liu, Xiuling Li, Chunhao Lin, Wenyue Zhang, Chee Hwee Tan, Shunung Liang, Baoming Luo, Xiaoding Xu & Phei Er Saw. (2020) Shape Matters: Comprehensive Analysis of Star-Shaped Lipid Nanoparticles. Frontiers in Pharmacology 11.
Crossref
Aline de Souza, Débora Soares Souza Marins, Samir Leite Mathias, Lis Marie Monteiro, Megumi Nishitani Yukuyama, Cauê Benito Scarim, Raimar Löbenberg & Nádia Araci Bou-Chacra. (2018) Promising nanotherapy in treating leishmaniasis. International Journal of Pharmaceutics 547:1-2, pages 421-431.
Crossref
Germán Abel Islan, Sergio Martin-Saldaña, Merari Tumin Chevalier, Vera Alejandra Alvarez & Guillermo Raúl Castro. 2018. ADME Processes in Pharmaceutical Sciences. ADME Processes in Pharmaceutical Sciences 135 165 .