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Drug Delivery Volume 27, 2020 - Issue 1
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Research Article

SPA: a peptide antagonist that acts as a cell-penetrating peptide for drug delivery

Jingjing Songa Institute of Pharmacology, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, Lanzhou University, Lanzhou, ChinaView further author information
,
Sujie Huangb Institute of Biochemistry and Molecular Biology, School of Life Sciences, Lanzhou University, Lanzhou, ChinaView further author information
,
Zhengzheng Zhangc Institute of Physiology, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, Lanzhou University, Lanzhou, ChinaView further author information
,
Bo Jiac Institute of Physiology, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, Lanzhou University, Lanzhou, ChinaView further author information
,
Huan Xiea Institute of Pharmacology, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, Lanzhou University, Lanzhou, ChinaView further author information
,
Ming Kaib Institute of Biochemistry and Molecular Biology, School of Life Sciences, Lanzhou University, Lanzhou, ChinaView further author information
&
Wei Zhangc Institute of Physiology, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, Lanzhou University, Lanzhou, ChinaCorrespondence[email protected]
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Pages 91-99 | Received 28 Oct 2019, Accepted 16 Dec 2019, Published online: 24 Dec 2019

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Xuan Li, Zheng Li, Yu-Qi Meng, Hui Qiao, Ke-Rong Zhai, Zhen-Qing Li, Shi-Lin Wei & Bin Li. (2023) Melittin kills A549 cells by targeting mitochondria and blocking mitophagy flux. Redox Report 28:1.
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Xuan Li, Sen Zhu, Zheng Li, Yu-Qi Meng, Su-Jie Huang, Qi-Yao Yu & Bin Li. (2022) Melittin induces ferroptosis and ER stress-CHOP-mediated apoptosis in A549 cells. Free Radical Research 56:5-6, pages 398-410.
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Yan Gao, Ke Men, Congbin Pan, Jingmei Li, Jieping Wu, Xiaohua Chen, Sibei Lei, Xiang Gao & Xingmei Duan. (2021) Functionalized DMP-039 Hybrid Nanoparticle as a Novel mRNA Vector for Efficient Cancer Suicide Gene Therapy. International Journal of Nanomedicine 16, pages 5211-5232.
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Ye Li, Zhun Zhang, Yezhuo Zhang, Jingcheng Hu & Yujie Fu. (2024) Design Principles for Smart Linear Polymer Ligand Carriers with Efficient Transcellular Transport Capabilities. International Journal of Molecular Sciences 25:13, pages 6826.
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Huaming Chen, Yunhong Wang, Hai Wang, Kun Zhang, Yunfei Liu, Qiangfeng Li, Chengli Li, Zhonghui Wen & Ziyu Chen. (2024) Biomimetic nanocarriers loaded with temozolomide by cloaking brain-targeting peptides for targeting drug delivery system to promote anticancer effects in glioblastoma cells. Heliyon 10:7, pages e28256.
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Ülo LangelÜlo Langel. 2023. CPP, Cell-Penetrating Peptides. CPP, Cell-Penetrating Peptides 133 150 .
Ülo LangelÜlo Langel. 2023. CPP, Cell-Penetrating Peptides. CPP, Cell-Penetrating Peptides 1 41 .
Ling Ma, Sujie Huang, Huan Xie, Panpan Ma, Bo Jia, Yufan Yao, Yuxuan Gao, Wenyuan Li, Jingjing Song & Wei Zhang. (2022) Influence of chain length on the anticancer activity of the antimicrobial peptide CAMEL with fatty acid modification. European Journal of Medicinal Chemistry 239, pages 114557.
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Zhongwen Zhu, Yufan Yao, Sujie Huang, Ling Ma, Jingjing Song & Wei Zhang. (2022) Antimicrobial and anti‐inflammatory activities of the neuropeptide antagonist SPA. Journal of Peptide Science 28:7.
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Sujie Huang, Zhongwen Zhu, Bo Jia, Wei Zhang & Jingjing Song. (2021) Design of acid‐activated cell‐penetrating peptides with nuclear localization capacity for anticancer drug delivery. Journal of Peptide Science 27:10.
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Prisca Boisguérin, Karidia Konate, Emilie Josse, Eric Vivès & Sébastien Deshayes. (2021) Peptide-Based Nanoparticles for Therapeutic Nucleic Acid Delivery. Biomedicines 9:5, pages 583.
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