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Drug Delivery Volume 29, 2022 - Issue 1
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Research Articles

3D-printed implantable devices with biodegradable rate-controlling membrane for sustained delivery of hydrophobic drugs

Camila J. Piccoa School of Pharmacy, Queen’s University Belfast, Belfast, UKORCID Iconhttps://orcid.org/0000-0002-1723-2065View further author information
ORCID Icon,
Juan Domínguez-Roblesa School of Pharmacy, Queen’s University Belfast, Belfast, UKORCID Iconhttps://orcid.org/0000-0002-8654-8434View further author information
ORCID Icon,
Emilia Utomoa School of Pharmacy, Queen’s University Belfast, Belfast, UKORCID Iconhttps://orcid.org/0000-0002-2306-7166View further author information
ORCID Icon,
Alejandro J. Paredesa School of Pharmacy, Queen’s University Belfast, Belfast, UKORCID Iconhttps://orcid.org/0000-0002-0414-8972View further author information
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Fabiana Volpe-Zanuttoa School of Pharmacy, Queen’s University Belfast, Belfast, UKORCID Iconhttps://orcid.org/0000-0003-0148-1080View further author information
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Dessislava Malinovab Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UKORCID Iconhttps://orcid.org/0000-0003-0784-5703View further author information
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Ryan F. Donnellya School of Pharmacy, Queen’s University Belfast, Belfast, UKORCID Iconhttps://orcid.org/0000-0002-0766-4147View further author information
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Eneko Larrañetaa School of Pharmacy, Queen’s University Belfast, Belfast, UKCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-3710-0438View further author information
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Pages 1038-1048 | Received 11 Feb 2022, Accepted 14 Mar 2022, Published online: 01 Apr 2022

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Jinal U. Pothupitiya, Christy Zheng & W. Mark Saltzman. (2022) Synthetic biodegradable polyesters for implantable controlled-release devices. Expert Opinion on Drug Delivery 19:10, pages 1351-1364.
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Vivek P Chavda, Gargi Jogi, Ana Cláudia Paiva-Santos & Ajeet Kaushik. (2022) Biodegradable and removable implants for controlled drug delivery and release application. Expert Opinion on Drug Delivery 19:10, pages 1177-1181.
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Eneko Larrañeta, Juan Domínguez-Robles, Andriana Margariti, Abdul W Basit & Álvaro Goyanes. (2022) 3D Printing for the Development of Implantable Devices for Cardiovascular Disease Treatment. Therapeutic Delivery 13:7, pages 359-362.
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Zelin Cao, Linbiao Xiang, Bai Sun, Kaikai Gao, Jiawei Yu, Guangdong Zhou, Xuegang Duan, Wentao Yan, Fulai Lin, Zhuoqun Li, Ruixin Wang, Yi Lv, Fenggang Ren, Yingmin Yao & Qiang Lu. (2024) A reversible implantable memristor for health monitoring applications. Materials Today Bio 26, pages 101096.
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Mohammed Chane, Desta Asefa & Dereje Kebebe Borga. (2024) Epidural and Intrathecal Drug Delivery Systems for Chronic Pain Management: Progress, Promises, and Challenges. Annals of Innovation in Medicine 2:2.
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Huanhuan Li, Qonita Kurnia Anjani, Aaron R. J. Hutton, Juan Luis Paris, Natalia Moreno‐Castellanos, Achmad Himawan, Eneko Larrañeta & Ryan F. Donnelly. (2024) Design of a Novel Delivery Efficiency Feedback System for Biphasic Dissolving Microarray Patches Based on Poly(Lactic Acid) and Moisture‐Indicating Silica. Advanced Healthcare Materials.
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Camila J. Picco, Qonita Kurnia Anjani, Ryan F. Donnelly & Eneko Larrañeta. (2024) An isocratic RP-HPLC-UV method for simultaneous quantification of tizanidine and lidocaine: application to in vitro release studies of a subcutaneous implant . Analytical Methods 16:7, pages 979-989.
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Virender Kumar, Harmanpreet Kaur, Anuradha Kumari, Goldy Hooda, Vandana Garg & Harish Dureja. (2023) Drug delivery and testing via 3D printing. Bioprinting 36, pages e00298.
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Juhaina M. Abu Ershaid, Lalitkumar K. Vora, Fabiana Volpe-Zanutto, Akmal H. Sabri, Ke Peng, Qonita K. Anjani, Peter E. McKenna, Anastasia Ripolin, Eneko Larrañeta, Helen O. McCarthy & Ryan F. Donnelly. (2023) Microneedle array patches for sustained delivery of fluphenazine: A micron scale approach for the management of schizophrenia. Biomaterials Advances 153, pages 213526.
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Laura M. Sanchez, Abigail K. Hopkins, Eduardo Espinosa, Eneko Larrañeta, Dessislava Malinova, Adam Nathan McShane, Juan Domínguez-Robles & Alejandro Rodríguez. (2023) Antioxidant cellulose nanofibers/lignin-based aerogels: a potential material for biomedical applications. Chemical and Biological Technologies in Agriculture 10:1.
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Elizabeth Magill, Sara Demartis, Elisabetta Gavini, Andi Dian Permana, Raghu Raj Singh Thakur, Muhammad Faris Adrianto, David Waite, Katie Glover, Camila J. Picco, Anna Korelidou, Usanee Detamornrat, Lalitkumar K. Vora, Linlin Li, Qonita Kurnia Anjani, Ryan F. Donnelly, Juan Domínguez-Robles & Eneko Larrañeta. (2023) Solid implantable devices for sustained drug delivery. Advanced Drug Delivery Reviews 199, pages 114950.
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Dhanalakshmi Vadivel, Nicolò Zitarosa & Daniele Dondi. (2023) Influence of pH on the release of an active principle from 3D printed carrageenan-k combined with alginate or xanthan gum. Heliyon 9:6, pages e16850.
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Moe Elbadawi, Abdul W. Basit & Simon Gaisford. (2023) Energy consumption and carbon footprint of 3D printing in pharmaceutical manufacture. International Journal of Pharmaceutics 639, pages 122926.
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Qi Zhu, Chang Liu, Sheng Tang, Wei Shen & Hian Kee Lee. (2023) Application of three dimensional-printed devices in extraction technologies. Journal of Chromatography A 1697, pages 463987.
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Juan Domínguez-Robles, Elias Cuartas-Gómez, Sean Dynes, Emilia Utomo, Qonita Kurnia Anjani, Usanee Detamornrat, Ryan F. Donnelly, Natalia Moreno-Castellanos & Eneko Larrañeta. (2023) Poly(caprolactone)/lignin-based 3D-printed dressings loaded with a novel combination of bioactive agents for wound-healing applications. Sustainable Materials and Technologies 35, pages e00581.
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Febri Annuryanti, Juan Domínguez-Robles, Qonita Kurnia Anjani, Muhammad Faris Adrianto, Eneko Larrañeta & Raghu Raj Singh Thakur. (2023) Fabrication and Characterisation of 3D-Printed Triamcinolone Acetonide-Loaded Polycaprolactone-Based Ocular Implants. Pharmaceutics 15:1, pages 243.
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Sarah A Stewart, Juan Domínguez-Robles, Ryan F Donnelly & Eneko Larrañeta. (2023) Evaluation of sterilisation techniques for 3D-printed implantable devices. RPS Pharmacy and Pharmacology Reports 2:1.
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Camila J. Picco, Emilia Utomo, Andrea McClean, Juan Domínguez-Robles, Qonita Kurnia Anjani, Fabiana Volpe-Zanutto, Peter E. McKenna, Jonathan G. Acheson, Dessislava Malinova, Ryan F. Donnelly & Eneko Larrañeta. (2023) Development of 3D-printed subcutaneous implants using concentrated polymer/drug solutions. International Journal of Pharmaceutics 631, pages 122477.
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Eveline E. M. van Kampen, Sejad Ayyoubi, Luc Willemsteijn, Kjeld J. C. van Bommel & Elisabeth J. Ruijgrok. (2022) The Quest for Child-Friendly Carrier Materials Used in the 3D Semi-Solid Extrusion Printing of Medicines. Pharmaceutics 15:1, pages 28.
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Shallu Kutlehria, Anisha D’Souza, Benjamin S. Bleier & Mansoor M. Amiji. (2022) Role of 3D Printing in the Development of Biodegradable Implants for Central Nervous System Drug Delivery. Molecular Pharmaceutics 19:12, pages 4411-4427.
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Zequan Zhao, Yin Lu, Yajun Mi, Jiajing Meng, Xia Cao & Ning Wang. (2022) Structural Flexibility in Triboelectric Nanogenerators: A Review on the Adaptive Design for Self-Powered Systems. Micromachines 13:10, pages 1586.
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Emilia Utomo, Juan Domínguez-Robles, Natalia Moreno-Castellanos, Sarah A. Stewart, Camila J. Picco, Qonita Kurnia Anjani, Jon Ander Simón, Iván Peñuelas, Ryan F. Donnelly & Eneko Larrañeta. (2022) Development of intranasal implantable devices for schizophrenia treatment. International Journal of Pharmaceutics 624, pages 122061.
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Anna Korelidou, Juan Domínguez-Robles, Elizabeth R. Magill, Magdalini Eleftheriadou, Victoria A. Cornelius, Ryan F. Donnelly, Andriana Margariti & Eneko Larrañeta. (2022) 3D-printed reservoir-type implants containing poly(lactic acid)/poly(caprolactone) porous membranes for sustained drug delivery. Biomaterials Advances 139, pages 213024.
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