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Research Article

Indole-3-carbinol induces G1 cell cycle arrest and apoptosis through aryl hydrocarbon receptor in THP-1 monocytic cell line

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Pages 506-514 | Received 23 Mar 2017, Accepted 24 Jul 2017, Published online: 16 Aug 2017

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Neda Abbaspour Sani, Mahsa Hasani, Anvarsadat Kianmehr, Saeed Mohammadi, Mehdi Sheikh Arabi & Yaghoub Yazdani. (2020) Enhanced nuclear translocation and activation of aryl hydrocarbon receptor (AhR) in THP-1 monocytic cell line by a novel niosomal formulation of indole-3-carbinol. Journal of Liposome Research 30:2, pages 117-125.
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Alevtina Y. Grishanova & Maria L. Perepechaeva. (2022) Aryl Hydrocarbon Receptor in Oxidative Stress as a Double Agent and Its Biological and Therapeutic Significance. International Journal of Molecular Sciences 23:12, pages 6719.
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Qi Li, Boyu Xia, Jingjing Wu, Xiaomei Yuan, Xu Lu, Chao Huang, Hongcheng Gu, Koulong Zheng, Qingsheng You & Kun Liu. (2022) Indole-3-Carbinol (I3C) Protects the Heart From Ischemia/Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Cellular Apoptosis in Mice. Frontiers in Pharmacology 13.
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Qiyue Tan, Guangyang Liu, Chenxi Zhao, Mingkun Gao, Xuan Zhang, Ge Chen, Lingyun Li, Xiaodong Huang, Yaowei Zhang, Jun Lv & Donghui Xu. (2022) Layered Double Hydroxide@Metal–Organic Framework Hybrids for Extraction of Indole-3-Carbinol From Cruciferous Vegetables. Frontiers in Nutrition 9.
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JY Lee, HM Lim, CM Lee, S-H Park & MJ Nam. (2021) Indole-3-carbinol inhibits the proliferation of colorectal carcinoma LoVo cells through activation of the apoptotic signaling pathway. Human & Experimental Toxicology 40:12, pages 2099-2112.
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Lixing Huang, Rongchao He, Youyu Zhang & Qingpi Yan. 2021. Antimicrobial Immune Response. Antimicrobial Immune Response.
A. G. Gunin & N. K. Kornilova. (2021) Aryl Hydrocarbon Receptor in Human Dermal Fibroblasts in the Aging Process. Advances in Gerontology 11:2, pages 139-144.
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Alka Ashok Singh, Maheshkumar Prakash Patil, Min-Jae Kang, Irvine Niyonizigiye & Gun-Do Kim. (2021) Biomedical application of Indole-3-carbinol: A mini-review. Phytochemistry Letters 41, pages 49-54.
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A. G. Gunin & N. N. Golubtzova. (2021) Aryl Hydrocarbon Receptor-Interacting Protein (AIP) in the Human Dermis with Aging. Advances in Gerontology 11:1, pages 59-63.
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Xiaoqian Zhang, Bin He, Ermei Chen, Juan Lu, Jie Wang, Hongcui Cao & Lanjuan Li. (2020) The aryl hydrocarbon receptor ligand ITE inhibits cell proliferation and migration and enhances sensitivity to drug‐resistance in hepatocellular carcinoma. Journal of Cellular Physiology 236:1, pages 178-192.
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Yenan Mo, Zhaoyu Lu, Lixin Wang, Chunlan Ji, Chuan Zou & Xusheng Liu. (2020) The Aryl Hydrocarbon Receptor in Chronic Kidney Disease: Friend or Foe?. Frontiers in Cell and Developmental Biology 8.
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Farnaz Eghbalpour, Mehrdad Aghaei, Mansour Ebrahimi, Mohammad Reza Tahsili, Masoud Golalipour, Saeed Mohammadi & Yaghoub Yazdani. (2020) Effect of indole-3-carbinol on transcriptional profiling of wound-healing genes in macrophages of systemic lupus erythematosus patients: an RNA sequencing assay. Lupus 29:8, pages 954-963.
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Yanbei Wu, Qiang He, Liangli Yu, Quynhchi Pham, Lumei Cheung, Young S. Kim, Thomas T. Y. Wang & Allen D. Smith. (2020) Indole-3-Carbinol Inhibits Citrobacter rodentium Infection through Multiple Pathways Including Reduction of Bacterial Adhesion and Enhancement of Cytotoxic T Cell Activity. Nutrients 12:4, pages 917.
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Joshua A. Walker, Sean Richards, Mostafa E. Belghasem, Nkiruka Arinze, Sung Bok Yoo, Joseph Y. Tashjian, Stephen A. Whelan, Norman Lee, Vijaya B. Kolachalama, Jean Francis, Katya Ravid, David Sherr & Vipul C. Chitalia. (2020) Temporal and tissue-specific activation of aryl hydrocarbon receptor in discrete mouse models of kidney disease. Kidney International 97:3, pages 538-550.
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Daniela Dolciami, Marco Ballarotto, Marco Gargaro, Luisa Carlota López-Cara, Francesca Fallarino & Antonio Macchiarulo. (2020) Targeting Aryl hydrocarbon receptor for next-generation immunotherapies: Selective modulators (SAhRMs) versus rapidly metabolized ligands (RMAhRLs). European Journal of Medicinal Chemistry 185, pages 111842.
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Shyam N. Sundar & Gary L. Firestone. 2020. Natural Products for Cancer Chemoprevention. Natural Products for Cancer Chemoprevention 489 516 .
Michelle Ly, Stefan Rentas, Ana Vujovic, Nicholas Wong, Steven Moreira, Joshua Xu, Nicholas Holzapfel, Sonam Bhatia, Damian Tran, Mark D. Minden, Jonathan S. Draper & Kristin J. Hope. (2019) Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance. Cancer Research 79:22, pages 5799-5811.
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J. E. Vorontsova, R. O. Cherezov, B. A. Kuzin & O. B. Simonova. (2019) Aryl-Hydrocarbon Receptor as a Potential Target for Anticancer Therapy. Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry 13:1, pages 36-54.
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Drew Neavin, Duan Liu, Balmiki Ray & Richard Weinshilboum. (2018) The Role of the Aryl Hydrocarbon Receptor (AHR) in Immune and Inflammatory Diseases. International Journal of Molecular Sciences 19:12, pages 3851.
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J.E. Vorontsova, R.O. Cherezov, B.A. Kuzin & O.B. Simonova. (2018) Aryl-hydrocarbon receptor as a potential target for anticancer therapy. Biomeditsinskaya Khimiya 64:5, pages 397-415.
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Hassan Askari, Sulail Fatima Rajani, Mansour Poorebrahim, Hamed Haghi-Aminjan, Ehsan Raeis-Abdollahi & Mohammad Abdollahi. (2018) A glance at the therapeutic potential of irisin against diseases involving inflammation, oxidative stress, and apoptosis: An introductory review. Pharmacological Research 129, pages 44-55.
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