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Original Articles

Optimization of L-asparaginase production from novel Enterobacter sp., by submerged fermentation using response surface methodology

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Achour Chergui, Lamia Trabelsi, Mounir M. Salem-Bekhit, Mohamed H. Mahmoud, Ehab I. Taha, Mohamed A. Ibrahim, Alessandro Erto, Ali Imessaoudene, Mouloud Kecha, Yacine Benguerba & Karim Houali. (2023) Optimization of intracellular L-Asparaginase production by Streptomyces paulus CA01 isolated from wheat bran using the response surface methodology. Biotechnology & Biotechnological Equipment 37:1.
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Rupkatha Mukherjee & Debabrata Bera. (2023) Effect of nutritional parameters on microbial production of L-Asparaginase by novel Brevibacillus borstelensis ML12. Preparative Biochemistry & Biotechnology 53:8, pages 995-1003.
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Archana Vimal & Awanish Kumar. (2017) Biotechnological production and practical application of L-asparaginase enzyme. Biotechnology and Genetic Engineering Reviews 33:1, pages 40-61.
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Articles from other publishers (22)

Manoj J. Dev, Shivaji B. Mawal & Rekha S. Singhal. (2023) l-Asparaginase from an acrylamide degrader, Cupriavidus oxalaticus ICTDB921: Production, kinetic modelling, purification and characterization. Biocatalysis and Agricultural Biotechnology 53, pages 102871.
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Doniya Elze Mathew, Anjana K. Vala, Ramalingam Dineshkumar, Jayashree Niharika, Ravindra Pal Singh, Pramod B. Shinde & Vaibhav A. Mantri. (2023) Performance evaluation and yield optimization of L-glutaminase free L-asparaginase from seaweed-associated bacteria. Bioresource Technology Reports 23, pages 101534.
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Sanyukta Darnal, Vijeta Patial, Virender Kumar, Subhash Kumar, Vijay Kumar, Yogendra S. Padwad & Dharam Singh. (2023) Biochemical characterization of extremozyme L-asparaginase from Pseudomonas sp. PCH199 for therapeutics. AMB Express 13:1.
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Shashi Kant Bhatia, Vijay Kumar, Virender Kumar, Ravi Kant Bhatia & Yung-Hun Yang. 2023. Basic Biotechniques for Bioprocess and Bioentrepreneurship. Basic Biotechniques for Bioprocess and Bioentrepreneurship 85 104 .
K. N. Abhini, Akhila B. Rajan, K. Fathimathu Zuhara & Denoj Sebastian. (2022) Response surface methodological optimization of l-asparaginase production from the medicinal plant endophyte Acinetobacter baumannii ZAS1. Journal of Genetic Engineering and Biotechnology 20:1.
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Payal G. Patel, Haresh Z. Panseriya, Anjana K. Vala, Bharti P. Dave & Haren B. Gosai. (2022) Exploring current scenario and developments in the field of microbial L-asparaginase production and applications: A review. Process Biochemistry 121, pages 529-541.
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V. P. Lailaja, T. G. Sumithra, K. J. Reshma, V. N. Anusree, P. V. Amala, T. G. Kishor & N. K. Sanil. (2022) Characterization of novel L-asparaginases having clinically safe profiles from bacteria inhabiting the hemolymph of the crab, Scylla serrata (Forskål, 1775). Folia Microbiologica 67:3, pages 491-505.
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Louise Lacalendola Tundisi, Diego de Freitas Coêlho, Alessandra Valéria de Sousa Faria, Adalberto Pessoa Junior, Elias Basile Tambourgi, Laura de Oliveira Nascimento, Edgar Silveira & Priscila Gava Mazzola. (2022) Two-Step Purification of L-Asparaginase from Acrylaway® L. Brazilian Journal of Pharmaceutical Sciences 58.
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Priyanka Gehlot, Manish Kumar & Nidhi Pareek. (2022) Production and purification of glutaminase free L-asparaginase from Lysinibacillus fusiformis and its appraisal in acrylamide mitigation of starchy foods. Materials Today: Proceedings 69, pages 64-73.
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Daniel Castro, Ana Sofia C. Marques, Mafalda R. Almeida, Gabriela B. de Paiva, Heitor B. S. Bento, Danielle B. Pedrolli, Mara G. Freire, Ana P. M. Tavares & Valéria C. Santos-Ebinuma. (2021) L-asparaginase production review: bioprocess design and biochemical characteristics. Applied Microbiology and Biotechnology 105:11, pages 4515-4534.
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A. Golbabaie, H. Nouri, H. Moghimi & A. Khaleghian. (2020) l ‐asparaginase production and enhancement by Sarocladium strictum : In vitro evaluation of anti‐cancerous properties . Journal of Applied Microbiology 129:2, pages 356-366.
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Kanti N. Mihooliya, Jitender Nandal, Alka Kumari, Sidhanta Nanda, Himanshu Verma & Debendra K. Sahoo. (2020) Studies on efficient production of a novel l-asparaginase by a newly isolated Pseudomonas resinovorans IGS-131 and its heterologous expression in Escherichia coli. 3 Biotech 10:4.
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Hoda Nouri, Hamid Moghimi & Ali khaleghian. (2020) Production and characterization of biochemical properties of L-Asparaginase by indigenous yeast isolated from soil of Iran. Koomesh Journal 22:1, pages 178-184.
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A. R. Reddy, K. A. Peele, S. Krupanidhi, K. V. Prabhakar & T. C. Venkateswarulu. (2018) Production of polyhydroxybutyrate from Acinetobacter nosocomialis RR20 strain using modified mineral salt medium: a statistical approach. International Journal of Environmental Science and Technology 16:10, pages 6447-6452.
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Noura El-Ahmady El-Naggar, Hassan Moawad, Nancy M. El-Shweihy, Sara M. El-Ewasy, Islam A. Elsehemy & Nayera A. M. Abdelwahed. (2019) Process development for scale-up production of a therapeutic L-asparaginase by Streptomyces brollosae NEAE-115 from shake flasks to bioreactor. Scientific Reports 9:1.
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Virender Kumar, Subhash Kumar, Sanyukta Darnal, Vijeta Patial, Anju Singh, Vikas Thakur, Sanjay Kumar & Dharam Singh. (2019) Optimized chromogenic dyes-based identification and quantitative evaluation of bacterial l-asparaginase with low/no glutaminase activity bioprospected from pristine niches in Indian trans-Himalaya. 3 Biotech 9:7.
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Asep Awaludin Prihanto, Indah Yanti, Mohammad Achsanil Murtazam & Yoga Dwi Jatmiko. (2019) Optimization of glutaminase-free L-asparaginase production using mangrove endophytic Lysinibacillus fusiformis B27. F1000Research 8, pages 1938.
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V. Antony JenilaJ. Joel Gnanadoss. (2018) Formulation of a Suitable Medium and its Optimization for Maximizing L-asparaginase Production from Endophytic Fungi Fusarium sp. LCJ273. Biosciences Biotechnology Research Asia 15:4, pages 887-898.
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Rajeswara Reddy Erva, T. C. Venkateswarulu & Bangaraiah Pagala. (2017) Multi level statistical optimization of l-asparaginase from Bacillus subtilis VUVD001. 3 Biotech 8:1.
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Yiing Yng Chow, Wei Shang Tan & Adeline Su Yien Ting. 2018. Anticancer Plants: Natural Products and Biotechnological Implements. Anticancer Plants: Natural Products and Biotechnological Implements 233 253 .
Dmitry D. Zhdanov, Vadim S. Pokrovsky, Marina V. Pokrovskaya, Svetlana S. Alexandrova, Mikhail A. Eldarov, Dmitry V. Grishin, Marsel M. Basharov, Yulia A. Gladilina, Olga V. Podobed & Nikolai N. Sokolov. (2017) Rhodospirillum rubrum l-asparaginase targets tumor growth by a dual mechanism involving telomerase inhibition. Biochemical and Biophysical Research Communications 492:2, pages 282-288.
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Archana Vimal & Awanish Kumar. (2017) In vitro screening and in silico validation revealed key microbes for higher production of significant therapeutic enzyme l-asparaginase. Enzyme and Microbial Technology 98, pages 9-17.
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