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Original Articles

Development and Validation of a Reversed Phase HPLC Method for Simultaneous Determination of Curcumin and Piperine in Human Plasma for Application in Clinical Pharmacological Studies

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Pages 2961-2974 | Received 12 May 2009, Accepted 10 Jun 2009, Published online: 12 Nov 2009

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Shanmugam Ramaswamy, Kuppusamy Gowthamarajan, Lalitha Priyanka Dwarampudi, Mahendran Bhaskaran & Madhuri Kadiyala. (2021) Analytical method development, validation and forced degradation studies for rutin, quercetin, curcumin, and piperine by RP-UFLC method. Drug Development and Industrial Pharmacy 47:4, pages 562-568.
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Christian Rafael Quijia & Marlus Chorilli. (2020) Characteristics, Biological Properties and Analytical Methods of Piperine: A Review. Critical Reviews in Analytical Chemistry 50:1, pages 62-77.
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AnishaA. D'Souza & PadmaV. Devarajan. (2013) RAPID AND SIMULTANEOUS HPLC ANALYSIS OF CURCUMIN AND ITS METABOLITE TETRAHYDROCURCUMIN FROM PLASMA AND LIVER HOMOGENATES. Journal of Liquid Chromatography & Related Technologies 36:13, pages 1788-1801.
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Articles from other publishers (12)

Rainer Ziegenhagen, Katharina Heimberg, Alfonso Lampen & Karen Ildico Hirsch-Ernst. (2021) Safety Aspects of the Use of Isolated Piperine Ingested as a Bolus. Foods 10:9, pages 2121.
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Dewi Setyaningsih, Yosua Agung Santoso, Yustina Sri Hartini, Yosi Bayu Murti, Wouter L.J. Hinrichs & Christine Patramurti. (2021) Isocratic high-performance liquid chromatography (HPLC) for simultaneous quantification of curcumin and piperine in a microparticle formulation containing Curcuma longa and Piper nigrum. Heliyon 7:3, pages e06541.
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Mohammed H. Alqarni, Prawez Alam, Ahmed I. Foudah, Magdy M. Muharram & Faiyaz Shakeel. (2021) Combining Normal/Reversed-Phase HPTLC with Univariate Calibration for the Piperine Quantification with Traditional and Ultrasound-Assisted Extracts of Various Food Spices of Piper nigrum L. under Green Analytical Chemistry Viewpoint. Molecules 26:3, pages 732.
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Elliott L. Rodriguez, Chenhua Zhang, Ashley G. Woolfork, Zhao Li, Cong Bi, Harleen Kaur, Anthony F. Juritsch, Régis Moreau & David S. Hage. (2021) Analysis of curcumin and piperine in biological samples by reversed-phase liquid chromatography with multi-wavelength detection. Journal of Chromatography B 1162, pages 122487.
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Shimba KAWASUE, Yohei SAKAGUCHI, Ena YANO, Tadashi HAYAMA, Reiko KOGA, Hideyuki YOSHIDA & Hitoshi NOHTA. (2019) Fluorous Derivatization Method for Selective Analysis of Curcumin with Liquid Chromatography-Tandem Mass Spectrometry. CHROMATOGRAPHY 40:3, pages 115-119.
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Pammi Praneetha, Ankit Balhara, Mayur K. Ladumor, Dilip Kumar Singh, Amol Patil, Jalvadi Preethi, Sunil Pokharkar, Abhijeet Yashwantrao Deshpande, Sanjeev Giri & Saranjit Singh. (2019) Characterization of stable and reactive metabolites of piperine formed on incubation with human liver microsomes. Journal of Mass Spectrometry 54:9, pages 738-749.
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Musaed Alkholief. (2019) Optimization of Lecithin-Chitosan nanoparticles for simultaneous encapsulation of doxorubicin and piperine. Journal of Drug Delivery Science and Technology 52, pages 204-214.
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David A. Bolliet. 2016. Chemesthesis. Chemesthesis 185 226 .
A. Thiel, S. Etheve, E. Fabian, W.R. Leeman & J.R. Plautz. (2015) Using in vitro/in silico data for consumer safety assessment of feed flavoring additives – A feasibility study using piperine. Regulatory Toxicology and Pharmacology 73:1, pages 73-84.
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Anette Thiel, Carin Buskens, Tina Woehrle, Stéphane Etheve, Ankie Schoenmakers, Markus Fehr & Paul Beilstein. (2014) Black pepper constituent piperine: Genotoxicity studies in vitro and in vivo. Food and Chemical Toxicology 66, pages 350-357.
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Imran Ali, Ashanul Haque & Kishwar Saleem. (2014) Separation and identification of curcuminoids in turmeric powder by HPLC using phenyl column. Anal. Methods 6:8, pages 2526-2536.
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Maria L.A.D. Lestari & Gunawan Indrayanto. 2014. 113 204 .

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