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Original Articles

Pirkle-Concept Chiral Stationary Phases for the HPLC Separation of Pharmaceutical Racemates

Pages 649-671 | Received 20 Jul 1994, Accepted 07 Sep 1994, Published online: 23 Sep 2006

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Read on this site (8)

Guy Felix & Alain Berthod. (2008) Part II: From Dermatologicals to Sensory Organ and Various Drugs. Separation & Purification Reviews 37:1-2, pages 1-227.
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Guy Felix & Alain Berthod. (2007) Commercial Chiral Stationary Phases for the Separations of Clinical Racemic Drugs. Separation & Purification Reviews 36:4, pages 285-481.
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Guy Félix. (2004) Overview of the Separation of Agrochemical Enantiomers on Commercial CSPs. Journal of Liquid Chromatography & Related Technologies 27:2, pages 237-273.
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HassanY. Aboul-Enein & IbrahimA. Al-Duraibi. (1998) Isocratic HPLC Separation of Several Racemic Drugs with Two Stereogenic Centers on a Pirkle Urea-Type Chiral Stationary Phase. Journal of Liquid Chromatography & Related Technologies 21:12, pages 1817-1831.
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M.M. Hefnawy & J.T. Stewart. (1998) HPLC Separation of Metyrosine Enantiomers as Methyl Esters Derivatized with 2, 3, 4, 6-Tetra-O-acetyl-β-D-glucopyranosyl Isothiocyanate. Journal of Liquid Chromatography & Related Technologies 21:3, pages 381-389.
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Madhusudhan Siluveru & JamesT. Stewart. (1997) Enantiomeric HPLC Separations of Chiral Local Anesthetics Using Cellulose Based Chiral Stationary Phases. Analytical Letters 30:6, pages 1167-1178.
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ThomasV. Alfredson, Robert Towne, Michelle Elliott, Bruce Griffin, Allassan Abubakari, Norman Dyson & DenisJ. Kertesz. (1996) Enantioselectivity of Azalanstat and Its Ketal Tosylate Intermediate in Chiral High Performance Liquid Chromatography Separations. Journal of Liquid Chromatography & Related Technologies 19:10, pages 1653-1668.
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HassanY. Aboul-Enein & LailaI. Abou-Basha. (1996) HPLC Separation of Nadolol and Enantiomers on Chiralcel OD Column. Journal of Liquid Chromatography & Related Technologies 19:3, pages 383-392.
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Articles from other publishers (17)

Priscila Aburachid Cardoso & Isabela Costa César. (2018) Chiral Method Development Strategies for HPLC using Macrocyclic Glycopeptide-Based Stationary Phases. Chromatographia 81:6, pages 841-850.
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Han Young Eom, Myunghee Kang, Seung Woo Kang, Unyong Kim, Joon Hyuk Suh, Junghyun Kim, Hyun-Deok Cho, Yura Jung, Dong-Hyug Yang & Sang Beom Han. (2016) Rapid chiral separation of racemic cetirizine in human plasma using subcritical fluid chromatography-tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 117, pages 380-389.
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Karen W. Phinney & Rodger W. Stringham. 2006. Chiral Separation Techniques. Chiral Separation Techniques 135 154 .
Hassan Aboul-Enein & Imran Ali. 2003. Chiral Separations By Liquid Chromatography And Related Technologies. Chiral Separations By Liquid Chromatography And Related Technologies 176 208 .
Sukumar Sakamuri, Istvan J Enyedy, Wahiduz A Zaman, Srihari R Tella, Alan P Kozikowski, Judith L Flippen-Anderson, Tivadar Farkas, Kenneth M Johnson & Shaomeng Wang. (2003) 2,3-Disubstituted quinuclidines as a novel class of dopamine transporter inhibitors. Bioorganic & Medicinal Chemistry 11:6, pages 1123-1136.
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Yaru Song, Defa Wang, Yuping Hu, Xiaoxia Chen, Yuguo Jiao & Dongyan Hou. (2003) Direct separation and quantitative determination of clenbuterol enantiomers by high performance liquid chromatography using an amide type chiral stationary phase. Journal of Pharmaceutical and Biomedical Analysis 31:2, pages 311-319.
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Ann Vercauteren, Guido Van der Weken, Tineke Vankeirsbilck, Hassan Y. Aboul‐Enein & Willy R. G. Baeyens. (2002) Enantiomeric separation of diuretics on a novel pirkle‐type chiral stationary phase. Biomedical Chromatography 16:7, pages 437-440.
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Shaomeng Wang, Sukumar Sakamuri, Istvan J. Enyedy, Alan P. Kozikowski, Wahiduz A. Zaman & Kenneth M. Johnson. (2001) Molecular Modeling, Structure?Activity Relationships and Functional Antagonism Studies of 4-Hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-Methylphenyl Ketones as a Novel Class of Dopamine Transporter Inhibitors. Bioorganic & Medicinal Chemistry 9:7, pages 1753-1764.
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Sašo Džeroski. 2001. Relational Data Mining. Relational Data Mining 339 364 .
Keith J. Duff. 2007. Encyclopedia of Analytical Chemistry. Encyclopedia of Analytical Chemistry.
Jacek Bojarski & Hassan Y. Aboul-Enein. (1999) Recent chromatographic and electrophoretic enantioseparations of cardiovascular drugs. Biomedical Chromatography 13:3, pages 197-208.
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Salvatore Caccamese & Grazia Principato. (1998) Resolution of the enantiomers of tetrahydrozoline by chiral HPLC. The racemization of the enantiomers via an imine–enamine tautomerism. Tetrahedron: Asymmetry 9:16, pages 2939-2945.
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R Ferretti, B Gallinella, F La Torre, L Zanitti, F Bonifacio & O Piccolo. (1998) Direct enantiomeric resolution of diphosphine and diphosphine oxide ligands by high-performance liquid chromatography. Journal of Chromatography A 795:2, pages 289-295.
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Karen L Williams, Lane C Sander & Stephen A Wise. (1997) Comparison of liquid and supercritical fluid chromatography for the separation of enantiomers on chiral stationary phases. Journal of Pharmaceutical and Biomedical Analysis 15:11, pages 1789-1799.
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Christopher H. Bryant. 1997. Inductive Logic Programming. Inductive Logic Programming 85 92 .
Jacek Bojarski & Hassan Y. Aboul-Enein. (1996) Recent Applications of Chromatographic Resolution of Enantiomers in Pharmaceutical Analysis. Biomedical Chromatography 10:6, pages 297-302.
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John G. Dorsey, William T. Cooper, Barbara A. Siles, Joe P. Foley & Howard G. Barth. (1996) Liquid Chromatography:  Theory and Methodology. Analytical Chemistry 68:12, pages 515-568.
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