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Pharmaceutical Development and Technology Volume 22, 2017 - Issue 7: Issue Theme: Pharmaceutical QbD, statistical analysis and experimental design optimization
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Research Article

Optimization of thermoreversible poloxamer gel system using QbD principle

Eunmi BanCollege of Pharmacy, CHA University, Seongnam, Korea;
,
Dong-Jin JangDepartment of Pharmaceutical Engineering, Inje University, Gimhae, Korea
,
Su-Jin KimCollege of Pharmacy, CHA University, Seongnam, Korea;
,
Mijung ParkCollege of Pharmacy, CHA University, Seongnam, Korea;
&
Aeri KimCollege of Pharmacy, CHA University, Seongnam, Korea; Correspondence[email protected]
Pages 939-945 | Received 21 Feb 2016, Accepted 21 Jun 2016, Published online: 01 Sep 2016

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Mahmoud M. El-Sonbaty, Hatem R. Ismail, Alaa A. Kassem, Ahmed M. Samy & Mohamed A. Akl. (2020) Mucoadhesive thermoreversible formulation of metoclopramide for rectal administration: a promising strategy for potential management of chemotherapy-induced nausea and vomiting. Pharmaceutical Development and Technology 25:5, pages 535-546.
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Articles from other publishers (11)

Leyla Beba Pozharani, Esra Baloglu, Kaya Suer, Emrah Guler, E. Vildan Burgaz & Imge Kunter. (2023) Development and optimization of in-situ gels for vaginal delivery of metronidazole and curcumin via box-behnken design: In vitro characterization and anti-trichomonas activity. Journal of Drug Delivery Science and Technology 86, pages 104739.
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Nisar Ul Khaliq, Juyeon Lee, Sangwoo Kim, Daekyung Sung & Hyungjun Kim. (2023) Pluronic F-68 and F-127 Based Nanomedicines for Advancing Combination Cancer Therapy. Pharmaceutics 15:8, pages 2102.
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Xiangchun Ruan, Jidong Hu, Lianshou Lu, Youwei Wang, Chunlian Tang, Faquan Liu, Xiuge Gao, Li Zhang, Hao Wu, Xianhui Huang & Qing Wei. (2022) Poloxamer 407/188 Binary Thermosensitive Gel as a Moxidectin Delivery System: In Vitro Release and In Vivo Evaluation. Molecules 27:10, pages 3063.
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ByungWook Kim, Eunmi Ban & Aeri Kim. (2021) Gelatin-Alginate Coacervates Optimized by DOE to Improve Delivery of bFGF for Wound Healing. Pharmaceutics 13:12, pages 2112.
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Débora Fretes Argenta, Bianca da Costa Bernardo, Andrés Felipe Chamorro, Paulo Ricardo Matos & Thiago Caon. (2021) Thermosensitive hydrogels for vaginal delivery of secnidazole as an approach to overcome the systemic side-effects of oral preparations. European Journal of Pharmaceutical Sciences 159, pages 105722.
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Mohamad A. Abou-Shamat, Jacqueline L. Stair, Stewart B. Kirton, Jesus Calvo-Castro & Michael T. Cook. (2020) A Design-of-Experiments approach to developing thermoresponsive gelators from complex polymer mixtures. Molecular Systems Design & Engineering 5:9, pages 1538-1546.
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Victor Oloruntoba Bankole, Michael Oluwole Osungunna, Claudia Regina Fernandes Souza, Sergio Luiz Salvador & Wanderley Pereira Oliveira. (2020) Spray-Dried Proliposomes: an Innovative Method for Encapsulation of Rosmarinus officinalis L. Polyphenols. AAPS PharmSciTech 21:5.
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Brian Leung, Priyanga Dharmaratne, Wei Yan, Ben C.L. Chan, Clara B.S. Lau, Kwok-Pui Fung, Margaret Ip & Sharon S.Y. Leung. (2020) Development of thermosensitive hydrogel containing methylene blue for topical antimicrobial photodynamic therapy. Journal of Photochemistry and Photobiology B: Biology 203, pages 111776.
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Mohamad A. Abou‐Shamat, Jesus Calvo‐Castro, Jacqueline L. Stair & Michael T. Cook. (2019) Modifying the Properties of Thermogelling Poloxamer 407 Solutions through Covalent Modification and the Use of Polymer Additives. Macromolecular Chemistry and Physics 220:16, pages 1900173.
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Muthuselvam Paulsamy, Chandrasekar Ponnusamy, Mohananarayanan Palanisami, Gayathri Nackeeran, SivaSakthi Paramasivam, Abimanyu Sugumaran, Ruckmani Kandasamy, Subramanian Natesan & Rajaguru Palanichamy. (2018) Nepafenac loaded silica nanoparticles dispersed in-situ gel systems: Development and characterization. International Journal of Biological Macromolecules 110, pages 336-345.
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Eunmi Ban, Mijung Park, Seonghee Jeong, Taekhyun Kwon, Eun-Hee Kim, Kiwon Jung & Aeri Kim. (2017) Poloxamer-Based Thermoreversible Gel for Topical Delivery of Emodin: Influence of P407 and P188 on Solubility of Emodin and Its Application in Cellular Activity Screening. Molecules 22:2, pages 246.
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