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Pharmaceutical Development and Technology Volume 24, 2019 - Issue 5
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Research Article

Brinzolamide–loaded nanoemulsions: ex vivo transcorneal permeation, cell viability and ocular irritation tests

Mohammad Mehdi MahboobianDepartment of Pharmaceutics, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan,Iran; ORCID Iconhttp://orcid.org/0000-0003-1395-1457
ORCID Icon,
Ali SeyfoddinDrug Delivery Research Group, School of Science, Auckland University of Technology, Auckland, New Zealand; ORCID Iconhttp://orcid.org/0000-0003-4343-9905
ORCID Icon,
Reza AboofazeliDepartment of Pharmaceutics, School of Pharmacy and Protein Technology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; ORCID Iconhttp://orcid.org/0000-0002-0803-0103
ORCID Icon,
Seyed Mohsen ForoutanDepartment of Pharmaceutics, School of Pharmacy and Protein Technology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Correspondence[email protected]
&
Ilva Dana RupenthalBuchanan Ocular Therapeutics Unit, Department of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New ZealandCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-5997-5994
ORCID Icon
Pages 600-606 | Received 12 May 2018, Accepted 08 Nov 2018, Published online: 15 Jan 2019

Citations (35)

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Mohammad Tavakoli, Mohammad Mehdi Mahboobian, Fatemeh Nouri & Mojdeh Mohammadi. (2021) Studying the ophthalmic toxicity potential of developed ketoconazole loaded nanoemulsion in situ gel formulation for ophthalmic administration. Toxicology Mechanisms and Methods 31:8, pages 572-580.
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Aashu Gupta, Kritika Nayak & Manju Misra. (2019) Cow ghee fortified ocular topical microemulsion; in vitro, ex vivo, and in vivo evaluation. Journal of Microencapsulation 36:7, pages 603-621.
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Shiding Li, Liangbo Chen & Yao Fu. (2023) Nanotechnology-based ocular drug delivery systems: recent advances and future prospects. Journal of Nanobiotechnology 21:1.
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Kevin Y. Wu, Said Ashkar, Shrieda Jain, Michael Marchand & Simon D. Tran. (2023) Breaking Barriers in Eye Treatment: Polymeric Nano-Based Drug-Delivery System for Anterior Segment Diseases and Glaucoma. Polymers 15:6, pages 1373.
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Yash Sharma, Kanak Chahar, Lopamudra Mishra, Lakshmi Kumari, Aarchi Singla, Preeti Patel, Dilpreet Singh & Balak Das Kurmi. (2023) Recent overviews on the drug delivery aspects and applications of brinzolamide for the management of glaucoma. Health Sciences Review 6, pages 100083.
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Seyedeh Negin Kassaee & Mohammad Mehdi Mahboobian. (2021) Besifloxacin-loaded ocular nanoemulsions: design, formulation and efficacy evaluation. Drug Delivery and Translational Research 12:1, pages 229-239.
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MS Samimi, MM Mahboobian & M Mohammadi. (2021) Ocular toxicity assessment of nanoemulsion in-situ gel formulation of fluconazole. Human & Experimental Toxicology 40:12, pages 2039-2047.
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Sima Talaei, Mohammad Mehdi Mahboobian & Mojdeh Mohammadi. (2020) Investigating the ocular toxicity potential and therapeutic efficiency of in situ gel nanoemulsion formulations of brinzolamide. Toxicology Research 9:4, pages 578-587.
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