Pharmaceutical Development and Technology, Volume 24, Issue 5 (2019)

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Pharmaceutical Development and Technology, Volume 24, Issue 5 (2019)

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Review Article

Review Article
Critical appraisal of commercially available suspending vehicles for extemporaneous compounding of cardiovascular medicines: physical and chemical stability mini review
Thilini Rasika Thrimawithana, Sebastian D’Amore, Youseph Dib, Nazanin Fadavi Firooz, Wafaa Fakhouri, Athraa Saeed & Ayman Allahham
Pages: 529-538
Published online: 20 Dec 2018
AbstractforCritical appraisal of commercially available suspending vehicles for extemporaneous compounding of cardiovascular medicines: physical and chemical stability mini review | Full Text | References | PDF (823.4 KB) | EPUB
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Research Article

Article
New in-situ gelling biopolymer-based matrix for bioavailability enhancement of glimepiride; in-vitro/in-vivo x-ray imaging and pharmacodynamic evaluations
Randa Hanie Awadeen, Mariza F. Boughdady & Mahasen Mohamed Meshali
Pages: 539-549
Published online: 27 Sep 2018
AbstractforNew in-situ gelling biopolymer-based matrix for bioavailability enhancement of glimepiride; in-vitro/in-vivo x-ray imaging and pharmacodynamic evaluations | Full Text | References | PDF (1.6 MB) | EPUB
  • 54 Views
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Article
Physical properties and solubility studies of Nifedipine-PEG 1450/HPMCAS-HF solid dispersions
Rahul V. Haware, Bhavani Prasad Vinjamuri, Monika Gavireddi, Vivek S. Dave, Deepak Gupta, Mahavir B. Chougule & William C. Stagner
Pages: 550-559
Published online: 05 Dec 2018
AbstractforPhysical properties and solubility studies of Nifedipine-PEG 1450/HPMCAS-HF solid dispersions | Full Text | References | PDF (2.4 MB) | EPUB
  • 227 Views
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Article
Development of a small-scale spray-drying approach for amorphous solid dispersions (ASDs) screening in early drug development
Aymeric Ousset, Céline Bassand, Pierre-François Chavez, Joke Meeus, Florent Robin, Martin Alexander Schubert, Pascal Somville & Kalliopi Dodou
Pages: 560-574
Published online: 06 Nov 2018
AbstractforDevelopment of a small-scale spray-drying approach for amorphous solid dispersions (ASDs) screening in early drug development | Full Text | References | PDF (3.4 MB) | EPUB
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Article
Silk fibroin nanoparticles for enhanced bio-macromolecule delivery to the retina
Pianpian Yang, Yixuan Dong, Di Huang, Chune Zhu, Hu Liu, Xin Pan & Chuanbin Wu
Pages: 575-583
Published online: 19 Mar 2019
AbstractforSilk fibroin nanoparticles for enhanced bio-macromolecule delivery to the retina | Full Text | References | PDF (2.1 MB) | EPUB
  • 374 Views
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Article
Optimization of a dry powder inhaler of ciprofloxacin-loaded polymeric nanomicelles by spray drying process
Mahdieh Farhangi, Arash Mahboubi, Farzad Kobarfard, Alireza Vatanara & Seyed Alireza Mortazavi
Pages: 584-592
Published online: 23 Apr 2019
AbstractforOptimization of a dry powder inhaler of ciprofloxacin-loaded polymeric nanomicelles by spray drying process | Full Text | References | PDF (2 MB) | EPUB
  • 305 Views
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Article
Increased in vitro leishmanicidal activity of octyl gallate loaded poly(methyl methacrylate) nanoparticles
Paulo Emilio Feuser, Maiko Luis Tonini, Amanda Virtuoso Jacques, Maria Claudia Santos da Silva, Mario Steindel, Claudia Sayer & Pedro Henrique Hermes de Araújo
Pages: 593-599
Published online: 23 Apr 2019
AbstractforIncreased in vitro leishmanicidal activity of octyl gallate loaded poly(methyl methacrylate) nanoparticles | Full Text | References | PDF (1.2 MB) | EPUB
  • 71 Views
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Article
Brinzolamide–loaded nanoemulsions: ex vivo transcorneal permeation, cell viability and ocular irritation tests
Mohammad Mehdi Mahboobian, Ali Seyfoddin, Reza Aboofazeli, Seyed Mohsen Foroutan & Ilva Dana Rupenthal
Pages: 600-606
Published online: 15 Jan 2019
AbstractforBrinzolamide–loaded nanoemulsions: ex vivo transcorneal permeation, cell viability and ocular irritation tests | Full Text | References | PDF (1.7 MB) | EPUB
  • 306 Views
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Article
Clarithromycin laurate salt: physicochemical properties and pharmacokinetics after oral administration in humans
Bashar A. Alkhalidi, Hatim S. AlKhatib, Mohammad Saleh, Saja Hamed, Yasser Bustanji, Nader Al Bujuq, Naji Najib, Susana Torrado-Susana & Al-Sayed Sallam
Pages: 607-615
Published online: 07 Dec 2018
AbstractforClarithromycin laurate salt: physicochemical properties and pharmacokinetics after oral administration in humans | Full Text | References | PDF (2 MB) | EPUB
  • 172 Views
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Article
Optimization of nimesulide-loaded solid lipid nanoparticles (SLN) by factorial design, release profile and cytotoxicity in human Colon adenocarcinoma cell line
Joana R. Campos, Ana R. Fernandes, Raquel Sousa, Joana F. Fangueiro, Prapaporn Boonme, Maria Luisa Garcia, Amelia M. Silva, Beatriz C. Naveros & Eliana B. Souto
Pages: 616-622
Published online: 04 Jan 2019
AbstractforOptimization of nimesulide-loaded solid lipid nanoparticles (SLN) by factorial design, release profile and cytotoxicity in human Colon adenocarcinoma cell line | Full Text | References | PDF (806.9 KB) | EPUB | Supplemental
  • 171 Views
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Article
In-vivo anti-tumor activity of a novel poloxamer-based thermosensitive in situ gel for sustained delivery of norcantharidin
Ming-Hua Xie, Min Ge, Jia-Bei Peng, Xiao-Rui Jiang, Ding-Sheng Wang, Li-Qiang Ji, Yin Ying & Zeng Wang
Pages: 623-629
Published online: 09 Dec 2018
AbstractforIn-vivo anti-tumor activity of a novel poloxamer-based thermosensitive in situ gel for sustained delivery of norcantharidin | Full Text | References | PDF (2.1 MB) | EPUB
  • 169 Views
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Article
Influence of protamine shell on nanoemulsions as a carrier for cyclosporine-A skin delivery
M. Javiera Alvarez-Figueroa, José María Abarca-Riquelme & José Vicente González-Aramundiz
Pages: 630-638
Published online: 07 Dec 2018
AbstractforInfluence of protamine shell on nanoemulsions as a carrier for cyclosporine-A skin delivery | Full Text | References | PDF (944.2 KB) | EPUB
  • 113 Views
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Article
Pre-formulation investigations for establishing a protocol for treosulfan handling and activation
Ibrahim El-Serafi, Orlaith Loy, Ying Zhao, Sandra Oerther & Jonas Mattsson
Pages: 639-648
Published online: 10 Jan 2019
AbstractforPre-formulation investigations for establishing a protocol for treosulfan handling and activation | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 2048 Views
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Open Access
Article
Effects of formulation development methods on the stability of model protein pharmaceuticals embedded in solid lipid matrices
Misbah Tabbassum & Farrukh Zeeshan
Pages: 649-662
Published online: 27 Jan 2019
AbstractforEffects of formulation development methods on the stability of model protein pharmaceuticals embedded in solid lipid matrices | Full Text | References | PDF (1.7 MB) | EPUB
  • 80 Views
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