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Pharmaceutical Development and Technology Volume 26, 2021 - Issue 3
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Research Articles

QbD approach to downstream processing of spray-dried amorphous solid dispersions – a case study

João HenriquesR&D, Drug Product Development, Hovione FarmaCiencia SA, Lisbon, PortugalCorrespondence[email protected]
,
Jorge MoreiraR&D, Drug Product Development, Hovione FarmaCiencia SA, Lisbon, Portugal
&
Slavomíra DoktorovováR&D, Drug Product Development, Hovione FarmaCiencia SA, Lisbon, PortugalORCID Iconhttps://orcid.org/0000-0001-5607-0241
ORCID Icon
Pages 269-277 | Received 29 May 2020, Accepted 10 Dec 2020, Published online: 04 Jan 2021

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Read on this site (1)

Phuong Tran & Jeong-Sook Park. (2021) Formulation of solid dispersion to improve dissolution and oral bioavailability of poorly soluble dexibuprofen. Pharmaceutical Development and Technology 26:4, pages 422-430.
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Articles from other publishers (4)

Jie Zhang, Minshan Guo, Minqian Luo & Ting Cai. (2023) Advances in the development of amorphous solid dispersions: The role of polymeric carriers. Asian Journal of Pharmaceutical Sciences 18:4, pages 100834.
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Nuno F. da Costa, Inês A. Santos, Ana I. Fernandes & João F. Pinto. (2022) Sulfonic Acid Derivatives in the Production of Stable Co-Amorphous Systems for Solubility Enhancement. Journal of Pharmaceutical Sciences 111:12, pages 3327-3339.
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Andreas Sauer, Shogo Warashina, Saurabh M Mishra, Ilja Lesser & Katja Kirchhöfer. (2021) Downstream processing of spray-dried ASD with hypromellose acetate succinate – Roller compaction and subsequent compression into high ASD load tablets. International Journal of Pharmaceutics: X 3, pages 100099.
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Derek Frank, Luke Schenck, Athanas Koynov, Yongchao Su, Yongjun Li & Narayan Variankaval. (2021) Optimizing Solvent Selection and Processing Conditions to Generate High Bulk-Density, Co-Precipitated Amorphous Dispersions of Posaconazole. Pharmaceutics 13:12, pages 2017.
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