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Research Article

Physicochemical Characterization and Dissolution Study of Solid Dispersions of Lovastatin with Polyethylene Glycol 4000 and Polyvinylpyrrolidone K30

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Pages 21-33 | Received 21 Aug 2006, Accepted 05 Sep 2006, Published online: 07 Oct 2008

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Jiaqi Li, Liuying Di, Xu Cheng, Weiwen Ji, Hongyu Piao, Gang Cheng & Meijuan Zou. (2020) The characteristics and mechanism of co-administration of lovastatin solid dispersion with kaempferol to increase oral bioavailability. Xenobiotica 50:5, pages 593-601.
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Muhammad Suhail, I-Hui Chiu, I-Ling Lin, Ming-Jun Tsai & Pao-Chu Wu. (2023) A Novel Approach of Polyethylene Glycol-4000 Hydrogels as Controlled Drug Carriers. Micro 3:2, pages 578-590.
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Amala Muniandy, Choy Sin Lee, Wen Huei Lim & Mallikarjuna Rao Pichika. (2021) Investigation of hyperbranched Poly(glycerol esteramide) as potential drug carrier in solid dispersion for solubility enhancement of lovastatin. Journal of Drug Delivery Science and Technology 61, pages 102237.
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Rahmat Talukder, Chase Reed, Thomas Dürig & Muhammad Hussain. (2011) Dissolution and Solid-State Characterization of Poorly Water-Soluble Drugs in the Presence of a Hydrophilic Carrier. AAPS PharmSciTech 12:4, pages 1227-1233.
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Komal R. Parmar, Sunny R. Shah & Navin R. Sheth. (2011) Preparation, Characterization, and In Vitro Evaluation of Ezetimibe Binary Solid Dispersions with Poloxamer 407 and PVP K30. Journal of Pharmaceutical Innovation 6:2, pages 107-114.
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Bibo Li, Ming Wen, Wei Li, Mei He, Xueheng Yang & Shaolin Li. (2011) Preparation and characterization of baicalin-poly -vinylpyrrolidone coprecipitate. International Journal of Pharmaceutics 408:1-2, pages 91-96.
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Zhen GE, Xin-xin ZHANG, Li GAN & Yong GAN. (2008) Redispersible, dry emulsion of lovastatin protects against intestinal metabolism and improves bioavailability 1 . Acta Pharmacologica Sinica 29:8, pages 990-997.
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Hui XU, Hiroya ABE, Makio NAITO, Hideki ICHIKAWA, Yoshinobu FUKUMORI & Shigehisa ENDOH. (2008) Immobilization of highly-dispersed single-walled carbon nanotubes in biocompatible and water-soluble solid matrix. Journal of the Ceramic Society of Japan 116:1357, pages 965-968.
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Muhammad Suhail, Ming-Chia Hung, I-Hui Chiu, Hamid Ullah, Ming-Jun Tsai & Pao-Chu Wu. (2022) Preparation, Swelling, and Release Kinetics of Polyethylene Glycol-4000 Based Hydrogels for Controlled Drug Release. SSRN Electronic Journal.
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