https://orcid.org/0000-0002-3874-5927
Citations (34)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (2)
E. E. Besong, P. J. Ashonibare, O. O. Obembe, M. A. Folawiyo, D. H. Adeyemi, M. A. Hamed, T. M. Akhigbe & R. E. Akhigbe. (2023) Zinc protects against lead-induced testicular damage via modulation of steroidogenic and xanthine oxidase/uric acid/caspase 3-mediated apoptotic signaling in male Wistar rats. The Aging Male 26:1.
Read now
Read now
O. A. Afolabi, M. A. Hamed, D. C. Anyogu, D. H. Adeyemi, A. F. Odetayo & R. E. Akhigbe. (2022) Atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative damage and apoptosis induced by ovarian ischaemia/reperfusion injury. Redox Report 27:1, pages 212-220.
Read now
Read now
Articles from other publishers (32)
Indrashis Bhattacharya, Souvik Sen Sharma & Subeer S. Majumdar. (2023) Etiology of Male Infertility: an Update. Reproductive Sciences.
Crossref
Crossref
Ken Lund, Olav Sivertsen Garvik, Signe Marie Aagaard, Line Riis Jølving, Michael Due Larsen, Per Damkier & Bente Mertz Nørgård. (2023) Paternal preconception exposure to non‐steroid anti‐inflammatory drugs or opioids and adverse birth outcomes: A nationwide registry‐based cohort study. Andrology.
Crossref
Crossref
Moses A. Hamed, Tunmise M. Akhigbe, Adetomiwa E. Adeogun, Oluwatosin B. Adesoye & Roland E. Akhigbe. (2023) Impact of organophosphate pesticides exposure on human semen parameters and testosterone: a systematic review and meta-analysis. Frontiers in Endocrinology 14.
Crossref
Crossref
Moses Agbomhere Hamed, Victor Olukayode Ekundina & Roland Eghoghosoa Akhigbe. (2023) Psychoactive drugs and male fertility: impacts and mechanisms. Reproductive Biology and Endocrinology 21:1.
Crossref
Crossref
Roland Eghoghosoa Akhigbe, Oladele A. Afolabi & Ayodeji Folorusho Ajayi. (2023) L-Arginine abrogates maternal and pre-pubertal codeine exposure-induced impaired spermatogenesis and sperm quality by modulating the levels of mRNA encoding spermatogenic genes. Frontiers in Endocrinology 14.
Crossref
Crossref
A. F. Ajayi, D. T. Oluwole, R. E. Akhigbe, M. A. Hamed & L. O. Ajayi. (2023) Proton Pump Dysfunction and Upregulation of Caspase-3 Activity via Oxidative-Sensitive Signaling Mediate Rohypnol-Induced Testicular Toxicity. Andrologia 2023, pages 1-15.
Crossref
Crossref
P. A. Oyedokun, R. E. Akhigbe, L. O. Ajayi & A. F. Ajayi. (2022) Impact of hypoxia on male reproductive functions. Molecular and Cellular Biochemistry 478:4, pages 875-885.
Crossref
Crossref
Adeniyi A. Adebayo, Leye J. Babatola, Christianah B. Fasanya & Ganiyu Oboh. (2022)
Persea americana
seed extract restores defective sperm quality and biochemical parameters relevant to reproduction in male wistar rats treated with cyclosporine A
. Journal of Food Biochemistry 46:11.
Crossref
Crossref
Roland Eghoghosoa Akhigbe, Oladele A. Afolabi & Ayodeji F. Ajayi. (2022) L-Arginine reverses maternal and pre-pubertal codeine exposure-induced sexual dysfunction via upregulation of androgen receptor gene and NO/cGMP signaling. PLOS ONE 17:9, pages e0274411.
Crossref
Crossref
Roland E. Akhigbe, Moses A. Hamed, Sulagna Dutta & Pallav Sengupta. (2022) Influence of ejaculatory abstinence period on semen quality of 5165 normozoospermic and oligozoospermic Nigerian men: A retrospective study. Health Science Reports 5:5.
Crossref
Crossref
Robert John Aitken. (2022) Role of sperm DNA damage in creating de-novo mutations in human offspring: the ‘post-meiotic oocyte collusion’ hypothesis. Reproductive BioMedicine Online 45:1, pages 109-124.
Crossref
Crossref
Mackenzie Newman, Heather Connery & Jonathan Boyd. (2022) Opioids and Vitamin C: Known Interactions and Potential for Redox-Signaling Crosstalk. Antioxidants 11:7, pages 1267.
Crossref
Crossref
Richard J. Bodnar. (2022) Endogenous opiates and behavior: 2020. Peptides 151, pages 170752.
Crossref
Crossref
R. E. Akhigbe, A. A. Oladipo, P. A. Oyedokun, M. A. Hamed, L. O. Okeleji & A. F. Ajayi. (2022) Upregulation of Uric Acid Production and Caspase 3 Signalling Mediates Rohypnol-Induced Cardiorenal Damage. Cardiovascular Toxicology 22:5, pages 419-435.
Crossref
Crossref
R.E. Akhigbe, O.S. Ebiwonjumi, L.O. Ajayi & A.F. Ajayi. (2022) Codeine alters female reproductive function by targeting ovarian steroidogenesis and folliculogenesis via the induction of oxidative stress, inflammation, and apoptosis. Reproductive Toxicology 109, pages 1-9.
Crossref
Crossref
M.A. Hamed, T.M. Akhigbe, R.E. Akhigbe, A.O. Aremu, P.A. Oyedokun, J.A. Gbadamosi, P.E. Anifowose, M.A. Adewole, O.O. Aboyeji, H.O. Yisau, G.O. Tajudeen, M.M. Titiloye, N.F. Ayinla & A.F. Ajayi. (2022) Glutamine restores testicular glutathione-dependent antioxidant defense and upregulates NO/cGMP signaling in sleep deprivation-induced reproductive dysfunction in rats. Biomedicine & Pharmacotherapy 148, pages 112765.
Crossref
Crossref
Robert John Aitken, Joël R. Drevet, Aron Moazamian & Parviz Gharagozloo. (2022) Male Infertility and Oxidative Stress: A Focus on the Underlying Mechanisms. Antioxidants 11:2, pages 306.
Crossref
Crossref
Kehinde Busuyi Dav, Adelusi Temitope I, Ayodeji Folorunsho, Akintola Olayemi Ad, Jegede Ayoola Isa, Akwu Bala Peter, Adebayo-Gege Grace, Ojediran Taiwo kayo & Olubunmi Simeon Oye. (2022) Effect of Vernonia amygdalina Leaves Extract on Testicular Functions of D-Galactose Induced Ageing Male Albino Rats. Journal of Pharmacology and Toxicology 17:1, pages 1-13.
Crossref
Crossref
RE Akhigbe & MA Hamed. (2021) Co-administration of HAART and antikoch triggers cardiometabolic dysfunction through an oxidative stress-mediated pathway. Lipids in Health and Disease 20:1.
Crossref
Crossref
A.F. Ogundola, R.E. Akhigbe, W.A. Saka, A.O. Adeniyi, O.S. Adeshina, D.O. Babalola & T.M. Akhigbe. (2021) Contraceptive potential of Andrographis paniculata is via androgen suppression and not induction of oxidative stress in male Wistar rats. Tissue and Cell 73, pages 101632.
Crossref
Crossref
R.E. Akhigbe, M.A. Hamed, A.F. Odetayo, T.M. Akhigbe, A.F. Ajayi & F.A.H. Ajibogun. (2021) Omega-3 fatty acid rescues ischaemia/perfusion-induced testicular and sperm damage via modulation of lactate transport and xanthine oxidase/uric acid signaling. Biomedicine & Pharmacotherapy 142, pages 111975.
Crossref
Crossref
Eva Tvrdá, Filip Benko, Tomáš Slanina & Stefan S. du Plessis. (2021) The Role of Selected Natural Biomolecules in Sperm Production and Functionality. Molecules 26:17, pages 5196.
Crossref
Crossref
R.E. Akhigbe, M.A. Hamed & A.O. Aremu. (2021) HAART exacerbates testicular damage and impaired spermatogenesis in anti-Koch-treated rats via dysregulation of lactate transport and glutathione content. Reproductive Toxicology 103, pages 96-107.
Crossref
Crossref
A.F. Ajayi & R.E. Akhigbe. (2021) Apoptotic inducement of neuronal cells by codeine: possible role of disrupted redox state and caspase 3 signaling. Heliyon 7:7, pages e07481.
Crossref
Crossref
Lydia Ajayi, Ademola Ayeleso, Temitope Oyedepo & Emmanuel Mukwevho. (2021) Ameliorative Potential of Hydroethanolic Leaf Extract of Parquetina nigrescens on d-Galactose-Induced Testicular Injury. Molecules 26:11, pages 3424.
Crossref
Crossref
W.A. Saka, R.E. Akhigbe, A.O. Abidoye, O.S. Dare & A.O. Adekunle. (2021) Suppression of uric acid generation and blockade of glutathione dysregulation by L-arginine ameliorates dichlorvos-induced oxidative hepatorenal damage in rats. Biomedicine & Pharmacotherapy 138, pages 111443.
Crossref
Crossref
R.E. Akhigbe, L.O. Ajayi & A.F. Ajayi. (2021) Codeine exerts cardiorenal injury via upregulation of adenine deaminase/xanthine oxidase and caspase 3 signaling. Life Sciences 273, pages 118717.
Crossref
Crossref
M.A. Hamed, A.O. Aremu & R.E. Akhigbe. (2021) Concomitant administration of HAART aggravates anti-Koch-induced oxidative hepatorenal damage via dysregulation of glutathione and elevation of uric acid production. Biomedicine & Pharmacotherapy 137, pages 111309.
Crossref
Crossref
Roland Eghoghosoa Akhigbe, Moses Agbomhere Hamed & Adeyemi Fatai Odetayo. (2021) HAART and anti‐Koch’s impair sexual competence, sperm quality and offspring quality when used singly and in combination in male Wistar rats. Andrologia 53:2.
Crossref
Crossref
David Tolulope Oluwole, Roland Eghoghosoa Akhigbe & Ayodeji Folorunsho Ajayi. (2020) Rohypnol‐induced sexual dysfunction is via suppression of hypothalamic‐pituitary‐testicular axis: An experimental study in rats. Andrologia 53:2.
Crossref
Crossref
R. E. Akhigbe, L. O. Ajayi, A. A. Adelakun, O. S. Olorunnisola & A. F. Ajayi. (2020) Codeine-induced hepatic injury is via oxido-inflammatory damage and caspase-3-mediated apoptosis. Molecular Biology Reports 47:12, pages 9521-9530.
Crossref
Crossref
A.F. Ajayi & R.E. Akhigbe. (2020) In vivo exposure to codeine induces reproductive toxicity: role of HER2 and p53/Bcl-2 signaling pathway. Heliyon 6:11, pages e05589.
Crossref
Crossref