Advanced search
Publication Cover
Expert Opinion on Therapeutic Patents Volume 30, 2020 - Issue 7
Submit an article Journal homepage
421
Views
16
CrossRef citations to date
0
Altmetric
Review

A 2018–2019 patent review of metallo beta-lactamase inhibitors

Nakita Reddya Catalysis and Peptide Research Unit, Westville Campus, University of KwaZulu-Natal, Durban, South AfricaORCID Iconhttps://orcid.org/0000-0003-4428-2241View further author information
ORCID Icon,
Mbongeni Shungubea Catalysis and Peptide Research Unit, Westville Campus, University of KwaZulu-Natal, Durban, South AfricaORCID Iconhttps://orcid.org/0000-0001-8405-584XView further author information
ORCID Icon,
Per I Arvidssona Catalysis and Peptide Research Unit, Westville Campus, University of KwaZulu-Natal, Durban, South Africa;b Science for Life Laboratory, Karolinska Institutet, Stockhlom, SwedenORCID Iconhttps://orcid.org/0000-0002-9453-6812View further author information
ORCID Icon,
Sooraj Baijnatha Catalysis and Peptide Research Unit, Westville Campus, University of KwaZulu-Natal, Durban, South AfricaORCID Iconhttps://orcid.org/0000-0001-7860-1779View further author information
ORCID Icon,
Hendrik G Krugera Catalysis and Peptide Research Unit, Westville Campus, University of KwaZulu-Natal, Durban, South AfricaORCID Iconhttps://orcid.org/0000-0003-0606-2053View further author information
ORCID Icon,
Thavendran Govenderc Department of Chemistry, University of Zululand, Empangeni, South AfricaORCID Iconhttps://orcid.org/0000-0003-2511-2503View further author information
ORCID Icon &
Tricia Naickera Catalysis and Peptide Research Unit, Westville Campus, University of KwaZulu-Natal, Durban, South AfricaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-7134-6258View further author information
ORCID Icon show all
Pages 541-555 | Received 06 Feb 2020, Accepted 06 May 2020, Published online: 20 May 2020

Citations (16)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Elsa Denakpo, Thierry Naas & Bogdan I. Iorga. (2023) An updated patent review of metallo-β-lactamase inhibitors (2020–2023). Expert Opinion on Therapeutic Patents 33:7-8, pages 523-538.
Read now

Articles from other publishers (15)

Elsa Denakpo, Guillaume Arlet, Alain Philippon & Bogdan I. Iorga. 2024. Metalloenzymes. Metalloenzymes 157 184 .
Kaylanne Montenegro, Claudia Flores, Ana Paula Alves Nascimento, Beatriz Oliveira Farias, Andressa S Gonçalves Brito, Mariana Magaldi, Aline Gimenez, Ivano de Filippis, Maysa Mandetta Clementino, Kayo Bianco, Enrico Saggioro & Paulo Barrocas. (2023) Occurrence of Klebsiella pneumoniae ST244 and ST11 extensively drug-resistant producing KPC, NDM, OXA-370 in wastewater, Brazil . Journal of Applied Microbiology 134:7.
Crossref
Mbongeni Shungube, Ayanda K. Hlophe, Letisha Girdhari, Victor T. Sabe, Byron B. Peters, Nakita Reddy, Kehinde F. Omolabi, Lloyd Chetty, Thilona Arumugam, Anil Chuturgoon, Hendrik G. Kruger, Per I. Arvidsson, Hua-Li Qin, Tricia Naicker & Thavendran Govender. (2023) Synthesis and biological evaluation of novel β-lactam-metallo β-lactamase inhibitors. RSC Advances 13:28, pages 18991-19001.
Crossref
Nakita Reddy, Letisha Girdhari, Mbongeni Shungube, Arnoldus C. Gouws, Byron K. Peters, Kamal K. Rajbongshi, Sooraj Baijnath, Sipho Mdanda, Thandokuhle Ntombela, Thilona Arumugam, Linda A. Bester, Sanil D. Singh, Anil Chuturgoon, Per I. Arvidsson, Glenn E. M Maguire, Hendrik G. Kruger, Thavendran Govender & Tricia Naicker. (2023) Neutralizing Carbapenem Resistance by Co-Administering Meropenem with Novel β-Lactam-Metallo-β-Lactamase Inhibitors. Antibiotics 12:4, pages 633.
Crossref
Byron K. Peters, Nakita Reddy, Mbongeni Shungube, Letisha Girdhari, Sooraj Baijnath, Sipho Mdanda, Lloyd Chetty, Thandokuhle Ntombela, Thilona Arumugam, Linda A. Bester, Sanil D. Singh, Anil Chuturgoon, Per I. Arvidsson, Glenn E. M. Maguire, Hendrik G. Kruger, Tricia Naicker & Thavendran Govender. (2023) In Vitro and In Vivo Development of a β-Lactam-Metallo-β-Lactamase Inhibitor: Targeting Carbapenem-Resistant Enterobacterales . ACS Infectious Diseases 9:3, pages 486-496.
Crossref
Laurent Gavara, Federica Verdirosa, Laurent Sevaille, Alice Legru, Giuseppina Corsica, Lionel Nauton, Paola Sandra Mercuri, Filomena Sannio, Filomena De Luca, Margot Hadjadj, Giulia Cerboni, Yen Vo Hoang, Patricia Licznar-Fajardo, Moreno Galleni, Jean-Denis Docquier & Jean-François Hernandez. (2022) 1,2,4-Triazole-3-thione analogues with an arylakyl group at position 4 as metallo-β-lactamase inhibitors. Bioorganic & Medicinal Chemistry 72, pages 116964.
Crossref
Sky Price, Radhika Mehta, Dominique Tan, Abigail Hinojosa, Pei W. Thomas, Tawanda Cummings, Walter Fast & Emily L. Que. (2022) Structural insights into the design of reversible fluorescent probes for metallo-β-lactamases NDM-1, VIM-2, and IMP-1. Journal of Inorganic Biochemistry 233, pages 111869.
Crossref
Zafar Iqbal, Jian Sun, Haikang Yang, Jingwen Ji, Lili He, Lijuan Zhai, Jinbo Ji, Pengjuan Zhou, Dong Tang, Yangxiu Mu, Lin Wang & Zhixiang Yang. (2022) Recent Developments to Cope the Antibacterial Resistance via β-Lactamase Inhibition. Molecules 27:12, pages 3832.
Crossref
Federica Verdirosa, Laurent Gavara, Laurent Sevaille, Giusy Tassone, Giuseppina Corsica, Alice Legru, Georges Feller, Giulia Chelini, Paola Sandra Mercuri, Silvia Tanfoni, Filomena Sannio, Manuela Benvenuti, Giulia Cerboni, Filomena De Luca, Ezeddine Bouajila, Yen Vo Hoang, Patricia Licznar‐Fajardo, Moreno Galleni, Cecilia Pozzi, Stefano Mangani, Jean‐Denis Docquier & Jean‐François Hernandez. (2022) 1,2,4‐Triazole‐3‐Thione Analogues with a 2‐Ethylbenzoic Acid at Position 4 as VIM‐type Metallo‐β‐Lactamase Inhibitors. ChemMedChem 17:7.
Crossref
Alice Legru, Federica Verdirosa, Jean-François Hernandez, Giusy Tassone, Filomena Sannio, Manuela Benvenuti, Pierre-Alexis Conde, Guillaume Bossis, Caitlyn A. Thomas, Michael W. Crowder, Melissa Dillenberger, Katja Becker, Cecilia Pozzi, Stefano Mangani, Jean-Denis Docquier & Laurent Gavara. (2021) 1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity. European Journal of Medicinal Chemistry 226, pages 113873.
Crossref
Laurent Gavara, Alice Legru, Federica Verdirosa, Laurent Sevaille, Lionel Nauton, Giuseppina Corsica, Paola Sandra Mercuri, Filomena Sannio, Georges Feller, Rémi Coulon, Filomena De Luca, Giulia Cerboni, Silvia Tanfoni, Giulia Chelini, Moreno Galleni, Jean-Denis Docquier & Jean-François Hernandez. (2021) 4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors. Bioorganic Chemistry 113, pages 105024.
Crossref
Guillermo Bahr, Lisandro J. González & Alejandro J. Vila. (2021) Metallo-β-lactamases in the Age of Multidrug Resistance: From Structure and Mechanism to Evolution, Dissemination, and Inhibitor Design. Chemical Reviews 121:13, pages 7957-8094.
Crossref
Alistair J. M. Farley, Yuri Ermolovich, Karina Calvopiña, Patrick Rabe, Tharindi Panduwawala, Jürgen Brem, Fredrik Björkling & Christopher J. Schofield. (2021) Structural Basis of Metallo-β-lactamase Inhibition by N -Sulfamoylpyrrole-2-carboxylates . ACS Infectious Diseases 7:6, pages 1809-1817.
Crossref
Roman S Tumskiy, Anastasiia V Tumskaia, Timophey E Pylaev, Elena S Avdeeva & Stella S Evstigneeva. (2021) Docking and antibacterial activity of novel nontoxic 5-arylidenepyrimidine-triones as inhibitors of NDM-1 and MetAP-1. Future Medicinal Chemistry.
Crossref
Elena O. Levina & Maria G. Khrenova. (2021) Metallo-β-Lactamases: Influence of the Active Site Structure on the Mechanisms of Antibiotic Resistance and Inhibition. Biochemistry (Moscow) 86:S1, pages S24-S37.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.