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Anticancer carbonic anhydrase inhibitors: a patent and literature update 2018-2022

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Pages 833-847 | Received 16 Mar 2022, Accepted 25 May 2022, Published online: 02 Jun 2022

Keep up to date with the latest research on this topic with citation updates for this article.

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Morteza Abdoli, Alessandro Bonardi, Claudiu T. Supuran & Raivis Žalubovskis. (2023) 4-Cyanamidobenzenesulfonamide derivatives: a novel class of human and bacterial carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1, pages 156-165.
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Claudiu T Supuran. (2023) Targeting carbonic anhydrases for the management of hypoxic metastatic tumors. Expert Opinion on Therapeutic Patents 0:0, pages 1-20.
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Tarfah Al-Warhi, Mostafa M. Elbadawi, Alessandro Bonardi, Alessio Nocentini, Ahmed A. Al-Karmalawy, Nada Aljaeed, Ohoud J. Alotaibi, Hatem A. Abdel-Aziz, Claudiu T. Supuran & Wagdy M. Eldehna. (2022) Design and synthesis of benzothiazole-based SLC-0111 analogues as new inhibitors for the cancer-associated carbonic anhydrase isoforms IX and XII. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 2635-2643.
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Mahmoud F. Abo-Ashour, Hadia Almahli, Alessandro Bonardi, Amira Khalil, Tarfah Al-Warhi, Sara T. Al-Rashood, Hatem A. Abdel-Aziz, Alessio Nocentini, Claudiu T. Supuran & Wagdy M. Eldehna. (2022) Enaminone-based carboxylic acids as novel non-classical carbonic anhydrases inhibitors: design, synthesis and in vitro biological assessment. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 2256-2264.
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Articles from other publishers (8)

Monalisa Mahapatra, Suman K. Mekap, Suvadeep Mal, Jyotirmaya Sahoo, Sanjeeb K. Sahoo & Sudhir K. Paidesetty. (2023) Coumaryl‐sulfonamide moiety: Unraveling their synthetic strategy and specificity toward  h CA IX/XII, facilitating anticancer drug development . Archiv der Pharmazie 356:4.
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Toni C. Denner, Niels Heise, Julian Zacharias, Oliver Kraft, Sophie Hoenke & René Csuk. (2023) Small Structural Differences Govern the Carbonic Anhydrase II Inhibition Activity of Cytotoxic Triterpene Acetazolamide Conjugates. Molecules 28:3, pages 1009.
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Claudiu T Supuran. (2023) Latest advances in specific inhibition of tumor-associated carbonic anhydrases. Future Medicinal Chemistry 15:1, pages 5-7.
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Samira Zareei, Maryam Mohammadi-Khanaposhtani, Mehdi Adib, Mohammad Mahdavi & Parham Taslimi. (2023) Sulfonamide-phosphonate hybrids as new carbonic anhydrase inhibitors: In vitro enzymatic inhibition, molecular modeling, and ADMET prediction. Journal of Molecular Structure 1271, pages 134114.
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Heba T. Abdel‐Mohsen, Mohamed A. Omar, Andrea Petreni & Claudiu T. Supuran. (2022) Novel 2‐substituted thioquinazoline‐benzenesulfonamide derivatives as carbonic anhydrase inhibitors with potential anticancer activity. Archiv der Pharmazie 355:12.
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Divya Rai, Satyajit Khatua & Srabani Taraphder. (2022) Structure and Dynamics of the Isozymes II and IX of Human Carbonic Anhydrase. ACS Omega 7:35, pages 31149-31166.
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Simone Giovannuzzi, Clemente Capasso, Alessio Nocentini & Claudiu T. Supuran. (2022) Continued Structural Exploration of Sulfocoumarin as Selective Inhibitor of Tumor-Associated Human Carbonic Anhydrases IX and XII. Molecules 27:13, pages 4076.
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Benjamin Brandes, Torje E. Orlamünde, Sophie Hoenke, Toni C. Denner, Ahmed Al-Harrasi & René Csuk. (2022) Selective and low-cost triterpene urea and amide derivatives of high cytotoxicity and selectivity. Results in Chemistry 4, pages 100610.
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