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Expert Opinion on Investigational Drugs Volume 28, 2019 - Issue 2
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Review

Investigational PI3K/AKT/mTOR inhibitors in development for endometrial cancer

Fabio BarraDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genova, Italy;Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genova, ItalyView further author information
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Giulio EvangelistiDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genova, Italy;Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genova, ItalyView further author information
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Lorenzo Ferro DesideriDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genova, Italy;Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genova, ItalyView further author information
,
Stefano Di DomenicoDepartment of Surgical and Diagnostic Sciences, IRCCS Ospedale Policlinico San Martino, University of Genova, ItalyView further author information
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Domenico FerraioliDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genova, Italy;Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genova, ItalyView further author information
,
Valerio Gaetano VelloneDepartment of Surgical and Diagnostic Sciences, IRCCS Ospedale Policlinico San Martino, University of Genova, ItalyView further author information
,
Franco De CianDepartment of Surgical and Diagnostic Sciences, IRCCS Ospedale Policlinico San Martino, University of Genova, ItalyView further author information
&
Simone FerreroDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genova, Italy;Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genova, ItalyCorrespondence[email protected]
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Pages 131-142 | Received 21 May 2018, Accepted 07 Dec 2018, Published online: 21 Dec 2018

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Wan Shu, Ziwei Wang, Rong Zhao, Rui Shi, Jun Zhang, Wei Zhang & Hongbo Wang. (2022) Exploration of the Effect and Potential Mechanism of Echinacoside Against Endometrial Cancer Based on Network Pharmacology and in vitro Experimental Verification. Drug Design, Development and Therapy 16, pages 1847-1863.
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Jingnan Liao, Huan Chen, Mingming Qi, Jinjin Wang & Mingyuan Wang. (2022) MLLT11-TRIL complex promotes the progression of endometrial cancer through PI3K/AKT/mTOR signaling pathway. Cancer Biology & Therapy 23:1, pages 211-224.
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Dajiang Liu, Xuehan Bi & Yongxiu Yang. (2022) Circular RNA hsa_circ_0011324 is involved in endometrial cancer progression and the evolution of its mechanism. Bioengineered 13:3, pages 7485-7499.
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Ying-Qi Feng, Shuang-Xi Gu, Yong-Shou Chen, Xu-Dong Gao, Yi-Xin Ren, Jian-Chao Chen, Yin-Ying Lu, Heng Zhang & Shuang Cao. (2020) Virtual Screening and Optimization of Novel mTOR Inhibitors for Radiosensitization of Hepatocellular Carcinoma. Drug Design, Development and Therapy 14, pages 1779-1798.
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Giulio Evangelisti, Fabio Barra, Melita Moioli, Paolo Sala, Sara Stigliani, Claudio Gustavino, Sergio Costantini & Simone Ferrero. (2020) Prexasertib: an investigational checkpoint kinase inhibitor for the treatment of high-grade serous ovarian cancer. Expert Opinion on Investigational Drugs 29:8, pages 779-792.
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Luigi Della Corte, Fabio Barra, Virginia Foreste, Pierluigi Giampaolino, Giulio Evangelisti, Simone Ferrero & Giuseppe Bifulco. (2020) Advances in paclitaxel combinations for treating cervical cancer. Expert Opinion on Pharmacotherapy 21:6, pages 663-677.
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