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Expert Opinion on Investigational Drugs Volume 28, 2019 - Issue 11
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Drug Evaluation

Tezepelumab: a novel biological therapy for the treatment of severe uncontrolled asthma

Giancarlo MaroneDepartment of Public Health, University of Naples Federico II, Naples, Italy;Azienda Ospedaliera Ospedali dei Colli - Monaldi Hospital Pharmacy, Naples, ItalyView further author information
,
Giuseppe SpadaroDepartment of Translational Medical Sciences and Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, Naples, Italy;WAO Center of Excellence, Naples, ItalyView further author information
,
Mariantonia BraileDepartment of Translational Medical Sciences and Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, Naples, Italy;WAO Center of Excellence, Naples, ItalyView further author information
,
Remo PotoDepartment of Translational Medical Sciences and Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, Naples, Italy;WAO Center of Excellence, Naples, ItalyView further author information
,
Gjada CriscuoloDepartment of Translational Medical Sciences and Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, Naples, Italy;WAO Center of Excellence, Naples, ItalyView further author information
,
Hadas PahimaPharmacology and Experimental Therapeutics Unit, School of Pharmacy, Institute for Drug Research, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, IsraelView further author information
,
Stefania LoffredoDepartment of Translational Medical Sciences and Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, Naples, Italy;WAO Center of Excellence, Naples, Italy;Institute of Experimental Endocrinology and Oncology “G. Salvatore” (IEOS), National Research Council (CNR), Naples, ItalyView further author information
,
Francesca Levi-SchafferPharmacology and Experimental Therapeutics Unit, School of Pharmacy, Institute for Drug Research, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, IsraelView further author information
&
Gilda VarricchiDepartment of Translational Medical Sciences and Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, Naples, Italy;WAO Center of Excellence, Naples, Italy;Institute of Experimental Endocrinology and Oncology “G. Salvatore” (IEOS), National Research Council (CNR), Naples, ItalyCorrespondence[email protected]
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Pages 931-940 | Received 29 Jul 2019, Accepted 23 Sep 2019, Published online: 10 Oct 2019

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Tanya M Laidlaw, Andrew Menzies-Gow, Scott Caveney, Joseph K Han, Nicole Martin, Elliot Israel, Jason K Lee, Jean-Pierre Llanos, Neil Martin, Ayman Megally, Bhavini Parikh, Sylvia Vong, Tobias Welte & Jonathan Corren. (2023) Tezepelumab Efficacy in Patients with Severe, Uncontrolled Asthma with Comorbid Nasal Polyps in NAVIGATOR. Journal of Asthma and Allergy 16, pages 915-932.
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Laren D Tan, Nolan Nguyen, Abdullah Alismail & Mario Castro. (2022) Management of Uncontrolled Asthma: A Framework for Novel and Legacy Biologic Treatments. Journal of Asthma and Allergy 15, pages 875-883.
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Rafael de Oliveira Resende, Vinícius José de Oliveira, Alessandro Sousa Correa, Pedro Trica de Araújo & Ernesto Akio Taketomi. (2022) COVID-19 scenario and recommendations on the continuity of immunobiological therapy in patients with atopic asthma in Brazil and Latin America. Expert Review of Respiratory Medicine 16:2, pages 211-220.
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Manisha Ramphul, David K H Lo & Erol A Gaillard. (2021) Precision Medicine for Paediatric Severe Asthma: Current Status and Future Direction. Journal of Asthma and Allergy 14, pages 525-538.
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Stefano Passanisi, Lucia Caminiti, Giuseppina Zirilli, Fortunato Lombardo, Giuseppe Crisafulli, Tommaso Aversa & Giovanni B Pajno. (2021) Biologics in food allergy: up-to-date. Expert Opinion on Biological Therapy 21:9, pages 1227-1235.
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Evgeniya Petrova & Alain Hovnanian. (2020) Advances in understanding of Netherton syndrome and therapeutic implications. Expert Opinion on Orphan Drugs 8:11, pages 455-487.
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Alessandro Vatrella, Angelantonio Maglio, Simona Pellegrino, Corrado Pelaia, Cristiana Stellato, Girolamo Pelaia & Carolina Vitale. (2020) Phenotyping severe asthma: a rationale for biologic therapy. Expert Review of Precision Medicine and Drug Development 5:4, pages 265-274.
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Kim Jackson & Sami L. Bahna. (2020) Hypersensitivity and adverse reactions to biologics for asthma and allergic diseases. Expert Review of Clinical Immunology 16:3, pages 311-319.
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