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Expert Opinion on Investigational Drugs Volume 29, 2020 - Issue 5
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Drug Evaluation

BIO 300: a promising radiation countermeasure under advanced development for acute radiation syndrome and the delayed effects of acute radiation exposure

Vijay K. Singha Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA;b Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, USACorrespondence[email protected]
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Thomas M Seedc Tech Micro Services, Bethesda, MD, USAView further author information
Pages 429-441 | Received 10 Mar 2020, Accepted 15 Apr 2020, Published online: 25 May 2020

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Vijay K. Singh, Meera Srivastava & Thomas M Seed. (2023) Protein biomarkers for radiation injury and testing of medical countermeasure efficacy: promises, pitfalls, and future directions. Expert Review of Proteomics 20:10, pages 221-246.
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Vojtěch Chmil, Alžběta Filipová & Aleš Tichý. (2023) Looking for the phoenix: the current research on radiation countermeasures. International Journal of Radiation Biology 99:8, pages 1148-1166.
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Tong Wu & Christie M. Orschell. (2023) The delayed effects of acute radiation exposure (DEARE): characteristics, mechanisms, animal models, and promising medical countermeasures. International Journal of Radiation Biology 99:7, pages 1066-1079.
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Vijay K. Singh & Thomas M Seed. (2023) Development of gamma-tocotrienol as a radiation medical countermeasure for the acute radiation syndrome: current status and future perspectives. Expert Opinion on Investigational Drugs 32:1, pages 25-35.
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Vijay K. Singh, Oluseyi O. Fatanmi, Stephen Y. Wise, Alana Carpenter, Sara Nakamura-Peek, Artur A. Serebrenik & Michael D. Kaytor. (2022) A novel oral formulation of BIO 300 confers prophylactic radioprotection from acute radiation syndrome in mice. International Journal of Radiation Biology 98:5, pages 958-967.
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Giacomo Sgalla, Alessia Comes, Marialessia Lerede & Luca Richeldi. (2021) COVID-related fibrosis: insights into potential drug targets. Expert Opinion on Investigational Drugs 30:12, pages 1183-1195.
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Vijay K Singh, Thomas M Seed & Amrita K Cheema. (2021) Metabolomics-based predictive biomarkers of radiation injury and countermeasure efficacy: current status and future perspectives. Expert Review of Molecular Diagnostics 21:7, pages 641-654.
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Articles from other publishers (2)

Vijay K. Singh & Thomas M. Seed. (2021) Entolimod as a radiation countermeasure for acute radiation syndrome. Drug Discovery Today 26:1, pages 17-30.
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Elena Obrador, Rosario Salvador, Juan I. Villaescusa, José M. Soriano, José M. Estrela & Alegría Montoro. (2020) Radioprotection and Radiomitigation: From the Bench to Clinical Practice. Biomedicines 8:11, pages 461.
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