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Expert Opinion on Investigational Drugs Volume 30, 2021 - Issue 9
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Drug Evaluation

Sprifermin: a recombinant human fibroblast growth factor 18 for the treatment of knee osteoarthritis

Jia Lia Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, China;b Department of Orthopedics, Zhujiang Hospital, Southern Medical University, Guangzhou, ChinaORCID Iconhttps://orcid.org/0000-0003-3572-3690View further author information
ORCID Icon,
Xiaoshuai Wanga Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, China;b Department of Orthopedics, Zhujiang Hospital, Southern Medical University, Guangzhou, ChinaORCID Iconhttps://orcid.org/0000-0002-3895-1384View further author information
ORCID Icon,
Guangfeng Ruana Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, ChinaView further author information
,
Zhaohua Zhua Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, ChinaORCID Iconhttps://orcid.org/0000-0003-3913-2564View further author information
ORCID Icon &
Changhai Dinga Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, China;c Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia;d Clinical Research Centre, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9479-730XView further author information
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Pages 923-930 | Received 20 Apr 2021, Accepted 23 Aug 2021, Published online: 03 Sep 2021

Citations (9)

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Yang Zhao, Qianhua Ou, Yu Cai, Guangfeng Ruan, Yan Zhang & Changhai Ding. (2023) Shedding light on experimental intra-articular drugs for treating knee osteoarthritis. Expert Opinion on Investigational Drugs 32:6, pages 509-524.
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Articles from other publishers (8)

Monica Paesa, Teresa Alejo, Felicito Garcia‐Alvarez, Manuel Arruebo & Gracia Mendoza. (2022) New insights in osteoarthritis diagnosis and treatment: Nano‐strategies for an improved disease management. WIREs Nanomedicine and Nanobiotechnology 15:2.
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X. Wang, T. Chen, W. Liang, T. Fan, Z. Zhu, P. Cao, G. Ruan, Y. Zhang, S. Chen, Q. Wang, S. Li, Y. Huang, M. Zeng, D.J. Hunter, J. Li & C. Ding. (2022) Synovitis mediates the association between bone marrow lesions and knee pain in osteoarthritis: data from the Foundation for the National Institute of Health (FNIH) Osteoarthritis Biomarkers Consortium. Osteoarthritis and Cartilage 30:9, pages 1270-1277.
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David M. Ornitz & Nobuyuki Itoh. (2022) New developments in the biology of fibroblast growth factors. WIREs Mechanisms of Disease 14:4.
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Win Min Oo. (2022) Prospects of Disease-Modifying Osteoarthritis Drugs. Clinics in Geriatric Medicine 38:2, pages 397-432.
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John Loughlin. (2022) Translating osteoarthritis genetics research: challenging times ahead. Trends in Molecular Medicine 28:3, pages 176-182.
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Yao Lu, Jieli Chen, Lihua Li, Yumei Cao, Yang Zhao, Xiaoyu Nie & Changhai Ding. (2022) Hierarchical functional nanoparticles boost osteoarthritis therapy by utilizing joint-resident mesenchymal stem cells. Journal of Nanobiotechnology 20:1.
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Heungdeok Kim, Jinwon Seo, Yunsin Lee, Kiwon Park, Thomas A. Perry, Nigel K. Arden, Ali Mobasheri & Heonsik Choi. (2022) The current state of the osteoarthritis drug development pipeline: a comprehensive narrative review of the present challenges and future opportunities. Therapeutic Advances in Musculoskeletal Disease 14, pages 1759720X2210859.
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Zongmian Song, Yusheng Li, Chunfeng Shang, Guowei Shang, Hongwei Kou, Jinfeng Li, Songfeng Chen & Hongjian Liu. (2021) Sprifermin: Effects on Cartilage Homeostasis and Therapeutic Prospects in Cartilage-Related Diseases. Frontiers in Cell and Developmental Biology 9.
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