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Expert Opinion on Investigational Drugs Volume 30, 2021 - Issue 12
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Review

Investigational therapies targeting CD3 for prevention and treatment of type 1 diabetes

Carmen MignognaDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy
,
Ernesto MaddaloniDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy
,
Luca D’OnofrioDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy
&
Raffaella BuzzettiDepartment of Experimental Medicine, Sapienza University of Rome, Rome, ItalyCorrespondence[email protected]
Pages 1209-1219 | Received 17 Oct 2021, Accepted 19 Dec 2021, Published online: 10 Jan 2022

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Nina Maria Fanaropoulou, Georgia C. Tsatsani, Theocharis Koufakis & Kalliopi Kotsa. (2023) Teplizumab: promises and challenges of a recently approved monoclonal antibody for the prevention of type 1 diabetes or preservation of residual beta cell function. Expert Review of Clinical Immunology 0:0, pages 1-12.
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Articles from other publishers (6)

Gurupreet S. Sethi, Donald T. Gracias, Rinkesh K. Gupta, Daniel Carr, Haruka Miki, Ricardo Da Silva Antunes & Michael Croft. (2023) Anti‐CD3 inhibits circulatory and tissue‐resident memory CD4 T cells that drive asthma exacerbations in mice . Allergy.
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Stéphane Dalle, Amar Abderrahmani & Eric Renard. (2023) Pharmacological inhibitors of β-cell dysfunction and death as therapeutics for diabetes. Frontiers in Endocrinology 14.
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Zhiying Zhang, Yinuo Li, Juyuan Shi, Li Zhu, Yinming Dai, Peiji Fu, Simon Liu, Michael Hong, Jiewen Zhang, Jian Wang & Chao Jiang. (2023) Lymphocyte-Related Immunomodulatory Therapy with Siponimod (BAF-312) Improves Outcomes in Mice with Acute Intracerebral Hemorrhage. Aging and disease 14:3, pages 966.
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James D LeFevre, Sneha L Cyriac, Adna Tokmic & Jamie M Pitlick. (2022) Anti-CD3 monoclonal antibodies for the prevention and treatment of type 1 diabetes: A literature review. American Journal of Health-System Pharmacy 79:23, pages 2099-2117.
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Raffaella Buzzetti, Ernesto Maddaloni, Jason Gaglia, R. David Leslie, F. Susan Wong & Bernhard O. Boehm. (2022) Adult-onset autoimmune diabetes. Nature Reviews Disease Primers 8:1.
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Eline M. Bunnik, Dide de Jongh & Emma Massey. (2022) Ethics of Early Clinical Trials of Bio-Artificial Organs. Transplant International 35.
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