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Shin Young Kim, Jung Wook Lim, Jin Woo Kim, So Yeon Park & Ju Tae Seo. (2015) Association between genetic polymorphisms in folate-related enzyme genes and infertile men with non-obstructive azoospermia. Systems Biology in Reproductive Medicine 61:5, pages 286-292.
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Dale Brincat, Sarah Catania, Pierre Schembri Wismayer & Jean Calleja-Agius. (2015) Male factors in ART outcome prediction. Gynecological Endocrinology 31:3, pages 169-175.
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Mateusz Kurzawski, Joanna Stefankiewicz, Rafał Kurzawa, Wanda Górnik, Tomasz Bączkowski & Marek Drozdzik. (2010) The SLC19A1 80G>A polymorphism is not associated with male infertility. Biomarkers 15:3, pages 217-220.
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Articles from other publishers (49)
KRanjith Babu, Manibalan Vijayaraman, Deepti Shastri & E Manivannan. (2023) Association of methylenetetrahydrofolate reductase polymorphism and male infertility in type 2 diabetes mellitus patients. BLDE University Journal of Health Sciences 8:1, pages 51.
Crossref
Crossref
Akash More, Ujwal Gajbe, Oluwabunmi Olatunji & Brij Singh. (2022) MTHFR Gene-Polymorphism and Infertile Men in Indian Population: A Systematic Literature Review. Cureus.
Crossref
Crossref
Anwar Madlool Al-janabi, Salih Mahdi Al-Khafaji & Shehab Ahmed Faris. (2022) Association of methyltetrahydrofolate reductase gene mutation, homocysteine level with semen quality of Iraqi infertile males. Egyptian Journal of Medical Human Genetics 23:1.
Crossref
Crossref
Fereshteh Aliakbari, Farkhondeh Pouresmaeili, Nahal Eshghifar, Zahra Zolghadr & Faezeh Azizi. (2020) Association of the MTHFR 677C>T and 1298A>C polymorphisms and male infertility risk: a meta-analysis. Reproductive Biology and Endocrinology 18:1.
Crossref
Crossref
Li-Juan Han, Xiao-Feng He & Xiang-Hua Ye. (2020) Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and male infertility risk. Medicine 99:51, pages e23662.
Crossref
Crossref
Noor Ullah, Atika Mansoor, Shazia Micheal, Bushra Mirza, Raheel Qamar, Kehkashan Mazhar & Saima Siddiqi. (2019)
MTHFR
polymorphisms as risk for male infertility in Pakistan and its comparison with socioeconomic status in the world
. Personalized Medicine 16:1, pages 35-49.
Crossref
Crossref
Igrid García-González, Roger Iván López-Díaz, José Reyes Canché-Pech, Alberto de Jesús Solís-Cárdenas, Jorge A. Flores-Ocampo, Renán Mendoza-Alcocer, Luis Fernando Herrera-Sánchez, Marco Antonio Jiménez-Rico, Adrián Alejandro Ceballos-López & María E. López-Novelo. (2018) Análisis de epistasia de polimorfismos de genes metabólicos asociados a cardiopatía isquémica en Yucatán. Clínica e Investigación en Arteriosclerosis 30:3, pages 102-111.
Crossref
Crossref
Igrid García-González, Roger Iván López-Díaz, José Reyes Canché-Pech, Alberto de Jesús Solís-Cárdenas, Jorge A. Flores-Ocampo, Renán Mendoza-Alcocer, Luis Fernando Herrera-Sánchez, Marco Antonio Jiménez-Rico, Adrián Alejandro Ceballos-López & María E. López-Novelo. (2018) Epistasis analysis of metabolic genes polymorphisms associated with ischemic heart disease in Yucatan. Clínica e Investigación en Arteriosclerosis (English Edition) 30:3, pages 102-111.
Crossref
Crossref
Nguyen Thi Trang, Vu Thi Huyen, Nguyen Thanh Tuan & Tran Duc Phan. (2018) Association of N-acetyltransferase-2 and glutathione S-transferase polymorphisms with idiopathic male infertility in Vietnam male subjects. Chemico-Biological Interactions 286, pages 11-16.
Crossref
Crossref
Prem Chandra Suthar, Pulakes Purkait, Kiran Uttaravalli, B. N. Sarkar, Rakshit Ameta & Mithun Sikdar. (2018) Glutathione S-transferase M1 and T1 null genotype frequency distribution among four tribal populations of western India. Journal of Genetics 97:1, pages 11-24.
Crossref
Crossref
Sezgin Gunes, Ashok Agarwal, Aysenur Ersoy & Ralf Henkel. 2018. Reproductomics. Reproductomics
21
45
.
R. Najafipour, S. Moghbelinejad, A. Aleyasin & A. Jalilvand. (2017)
Effect of B9 and B12 vitamin intake on semen parameters and fertility of men with
MTHFR
polymorphisms
. Andrology 5:4, pages 704-710.
Crossref
Crossref
M Irfan, M Ismail, M Azhar Beg, A Shabbir, A Rashid Kayani & G Kaukab Raja. (2016)
Association of the
MTHFR
C677T (rs1801133) polymorphism with idiopathic male infertility in a local Pakistani population
. Balkan Journal of Medical Genetics 19:1, pages 51-62.
Crossref
Crossref
R. J. Aitken, H. M. Flanagan, H. Connaughton, S. Whiting, A. Hedges & M. A. Baker. (2016)
Involvement of homocysteine, homocysteine thiolactone, and paraoxonase type 1 (
PON
‐1) in the etiology of defective human sperm function
. Andrology 4:2, pages 345-360.
Crossref
Crossref
Kang Liu, Ruizhe Zhao, Min Shen, Jiaxin Ye, Xiao Li, Yuan Huang, Lixin Hua, Zengjun Wang & Jie Li. (2015) Role of genetic mutations in folate-related enzyme genes on Male Infertility. Scientific Reports 5:1.
Crossref
Crossref
Hossein Nikzad, Mohammad Karimian, Kobra Sareban, Maryam Khoshsokhan & Abasalt Hosseinzadeh Colagar. (2015) MTHFR-Ala222Val and male infertility: a study in Iranian men, an updated meta-analysis and an in silico-analysis. Reproductive BioMedicine Online 31:5, pages 668-680.
Crossref
Crossref
Mancheng Gong, Wenjing Dong, Tingyu He, Zhirong Shi, Guiying Huang, Rui Ren, Sichong Huang, Shaopeng Qiu & Runqiang Yuan. (2015) MTHFR 677C>T Polymorphism Increases the Male Infertility Risk: A Meta-Analysis Involving 26 Studies. PLOS ONE 10:3, pages e0121147.
Crossref
Crossref
Tarek M. Hussein & Dalia I. Elneely. (2014) Y-chromosome microdeletions and the MTHFR C677T polymorphism in Egyptian men with nonobstructive azoospermia. Human Andrology 4:3, pages 66-70.
Crossref
Crossref
Doaa S. Mfady, May F. Sadiq, Omar F. Khabour, AbdulFattah S. Fararjeh, Aymen Abu-Awad & Yousef Khader. (2014) Associations of variants in MTHFR and MTRR genes with male infertility in the Jordanian population. Gene 536:1, pages 40-44.
Crossref
Crossref
Hena Naqvi, Syed Rizwan Hussain, Mohammad Kaleem Ahmad, Farzana Mahdi, Shyam Pyari Jaiswar, Satya Narayain Shankhwar & Abbas Ali Mahdi. (2013) Role of 677C→T polymorphism a single substitution in methylenetetrahydrofolate reductase (MTHFR) gene in North Indian infertile men. Molecular Biology Reports 41:2, pages 573-579.
Crossref
Crossref
Alexandra S. Weiner, Uljana A. Boyarskikh, Elena N. Voronina, Alexey E. Tupikin, Olga V. Korolkova, Igor V. Morozov & Maxim L. Filipenko. (2014) Polymorphisms in folate-metabolizing genes and risk of idiopathic male infertility: a study on a Russian population and a meta-analysis. Fertility and Sterility 101:1, pages 87-94.e3.
Crossref
Crossref
Cristina Camprubí, Marta Pladevall, Mark Grossmann, Nicolás Garrido, Maria C. Pons & Joan Blanco. (2013) Lack of association of MTHFR rs1801133 polymorphism and CTCFL mutations with sperm methylation errors in infertile patients. Journal of Assisted Reproduction and Genetics 30:9, pages 1125-1131.
Crossref
Crossref
Wei Wu, Jing Lu, Qiuqin Tang, Simin Zhang, Beilei Yuan, Jing Li, Di Wu, Hong Sun, Chuncheng Lu, Yankai Xia, Daozhen Chen, Jiahao Sha & Xinru Wang. (2013) GSTM1 and GSTT1 null polymorphisms and male infertility risk: an updated meta-analysis encompassing 6934 subjects. Scientific Reports 3:1.
Crossref
Crossref
Nishi Gupta, Saumya Sarkar, Archana David, Pravin Kumar Gangwar, Richa Gupta, Gita Khanna, Satya Narayan Sankhwar, Anil Khanna & Singh Rajender. (2013) Significant Impact of the MTHFR Polymorphisms and Haplotypes on Male Infertility Risk. PLoS ONE 8:7, pages e69180.
Crossref
Crossref
Hou-Qun YingYue QiXiao-Ying PuShuo-Ran LiuZhou-Cun A. (2013) Association of GSTM1 and GSTT1 Genes with the Susceptibility to Male Infertility: Result from a Meta-Analysis. Genetic Testing and Molecular Biomarkers 17:7, pages 535-542.
Crossref
Crossref
Kiran Singh & Deepika Jaiswal. (2013) One-Carbon Metabolism, Spermatogenesis, and Male Infertility. Reproductive Sciences 20:6, pages 622-630.
Crossref
Crossref
He-Ping Kan, Fang-Lei Wu, Wen-Bin Guo, Yong-Zhong Wang, Jing-Ping Li, Yu-Qi Huang, Shu-Guang Li & Jian-Ping Liu. (2013) Null genotypes of GSTM1 and GSTT1 contribute to male factor infertility risk: a meta-analysis. Fertility and Sterility 99:3, pages 690-696.
Crossref
Crossref
Xin Li, Jinhong Pan, Qigui Liu, Enqing Xiong, Zhiwen Chen, Zhansong Zhou, Yongping Su & Gensheng Lu. (2012) Glutathione S-transferases gene polymorphisms and risk of male idiopathic infertility: a systematic review and meta-analysis. Molecular Biology Reports 40:3, pages 2431-2438.
Crossref
Crossref
Min Tang, Shangqian Wang, Wei Wang, Qiang Cao, Chao Qin, Bianjiang Liu, Pengchao Li & Wei Zhang. (2012) The glutathione-S-transferase gene polymorphisms (GSTM1 and GSTT1) and idiopathic male infertility risk: A meta-analysis. Gene 511:2, pages 218-223.
Crossref
Crossref
Wu Chengyong, Yang Man, Lin Mei, Li Liping & Wen Xuezhen. (2012) GSTM1 null genotype contributes to increased risk of male infertility: a meta-analysis. Journal of Assisted Reproduction and Genetics 29:8, pages 837-845.
Crossref
Crossref
Abdelmajid Eloualid, Omar Abidi, Majida Charif, Brahim El houate, Houda Benrahma, Noureddine Louanjli, Elbakkay Chadli, Maria Ajjemami, Abdelhamid Barakat, Anu Bashamboo, Ken McElreavey, Houria Rhaissi & Hassan Rouba. (2012) Association of the MTHFR A1298C Variant with Unexplained Severe Male Infertility. PLoS ONE 7:3, pages e34111.
Crossref
Crossref
Deepika Jaiswal, Ravindra Sah, Neeraj K. Agrawal, U. S. Dwivedi, Sameer Trivedi & Kiran Singh. (2012) Combined Effect of GSTT1 and GSTM1 Polymorphisms on Human Male Infertility in North Indian Population. Reproductive Sciences 19:3, pages 312-316.
Crossref
Crossref
Bingbing Wei, Zhuoqun Xu, Jun Ruan, Ming Zhu, Ke Jin, Deqi Zhou, Zeqiao Xu, Qiang Hu, Qiang Wang & Zhirong Wang. (2011) MTHFR 677C>T and 1298A>C polymorphisms and male infertility risk: a meta-analysis. Molecular Biology Reports 39:2, pages 1997-2002.
Crossref
Crossref
Annelien Massart, Willy Lissens, Herman Tournaye & Katrien Stouffs. (2011) Genetic causes of spermatogenic failure. Asian Journal of Andrology 14:1, pages 40-48.
Crossref
Crossref
Laurel E Murphy, James L Mills, Anne M Molloy, Cong Qian, Tonia C Carter, Helena Strevens, Dag Wide-Swensson, Aleksander Giwercman & Richard J Levine. (2011) Folate and vitamin B12 in idiopathic male infertility. Asian Journal of Andrology 13:6, pages 856-861.
Crossref
Crossref
Nishi Gupta, Saraswati Gupta, Madhukar Dama, Archana David, Geeta Khanna, Anil Khanna & Singh Rajender. (2011) Strong Association of 677 C>T Substitution in the MTHFR Gene with Male Infertility - A Study on an Indian Population and a Meta-Analysis. PLoS ONE 6:7, pages e22277.
Crossref
Crossref
Mohammad Reza Safarinejad, Nayyer Shafiei & Shiva Safarinejad. (2011) Relationship Between Genetic Polymorphisms of Methylenetetra hydrofolate Reductase (C677T, A1298C, and G1793A) as Risk Factors for Idiopathic Male Infertility. Reproductive Sciences 18:3, pages 304-315.
Crossref
Crossref
Mohammad Reza Safarinejad, Nayyer Shafiei & Shiva Safarinejad. (2010) The association of glutathione-S-transferase gene polymorphisms (GSTM1, GSTT1, GSTP1) with idiopathic male infertility. Journal of Human Genetics 55:9, pages 565-570.
Crossref
Crossref
Alexey V. Polonikov, Sergey L. Yarosh, Elena V. Kokhtenko, Nina I. Starodubova, Sergey P. Pakhomov & Valentina S. Orlova. (2010) The functional genotype of glutathione S-transferase T1 gene is strongly associated with increased risk of idiopathic infertility in Russian men. Fertility and Sterility 94:3, pages 1144-1147.
Crossref
Crossref
Valentina Djordjevic, A. Nikolic, M. Ljujic, A. Nestorovic, M. Ristanovic, C. Tulic & D. Radojkovic. (2010) Combined effect of GSTM1 gene deletion, GSTT1 gene deletion and MTHFR C677T mutation in male infertility. Archives of Biological Sciences Arhiv za bioloske nauke 62:3, pages 525-530.
Crossref
Crossref
Ozlem Tunc & Kelton Tremellen. (2009) Oxidative DNA damage impairs global sperm DNA methylation in infertile men. Journal of Assisted Reproduction and Genetics 26:9-10, pages 537-544.
Crossref
Crossref
N. Khazamipour, M. Noruzinia, P. Fatehmanesh, M. Keyhanee & P. Pujol. (2009) MTHFR promoter hypermethylation in testicular biopsies of patients with non-obstructive azoospermia: the role of epigenetics in male infertility. Human Reproduction 24:9, pages 2361-2364.
Crossref
Crossref
T. Forges, H. Pellanda, C. Diligent, P. Monnier & J.-L. Guéant. (2008) Les folates : quel impact sur la fertilité ?. Gynécologie Obstétrique & Fertilité 36:9, pages 930-939.
Crossref
Crossref
Ivan Nisevic, Jelena Dinic, Aleksandra Nikolic, Valentina Djordjevic, Snezana Lukic, Milenko Ugljesic, Marina Andjelic‐Jelic, Natasa Petrovic‐Stanojevic & Dragica Radojkovic. (2008) MTHFR C677T polymorphism in chronic pancreatitis and pancreatic adenocarcinoma. Cell Biochemistry and Function 26:6, pages 659-663.
Crossref
Crossref
Thierry Forges, P. Monnier-Barbarino, J.M. Alberto, R.M. Guéant-Rodriguez, J.L. Daval & J.L. Guéant. (2007) Impact of folate and homocysteine metabolism on human reproductive health. Human Reproduction Update 13:3, pages 225-238.
Crossref
Crossref
Varinderpal S. Dhillon, Mohd Shahid & Syed Akhtar Husain. (2007) Associations of MTHFR DNMT3b 4977 bp deletion in mtDNA and GSTM1 deletion, and aberrant CpG island hypermethylation of GSTM1 in non-obstructive infertility in Indian men. MHR: Basic science of reproductive medicine 13:4, pages 213-222.
Crossref
Crossref
Alberto Ferlin, Florina Raicu, Valentina Gatta, Daniela Zuccarello, Giandomenico Palka & Carlo Foresta. (2007) Male infertility: role of genetic background. Reproductive BioMedicine Online 14:6, pages 734-745.
Crossref
Crossref
Frank Tüttelmann, Ewa Rajpert-De Meyts, Eberhard Nieschlag & Manuela Simoni. (2007) Gene polymorphisms and male infertility – a meta-analysis and literature review. Reproductive BioMedicine Online 15:6, pages 643-658.
Crossref
Crossref
Alberto Ferlin, Barbara Arredi & Carlo Foresta. (2006) Genetic causes of male infertility. Reproductive Toxicology 22:2, pages 133-141.
Crossref
Crossref