The tyrosine kinase inhibitor imatinib mesylate delays prion neuroinvasion by inhibiting prion propagation in the periphery

Seong-Wook Yun Institute of Virology and Immunobiology, University of Wurzburg, Wurzburg, Germany; Clinical Neurochemistry and NPF Center of Excellence, Clinic of Psychiatry and Psychotherapy, University of Wurzburg, Wurzburg, Germany

Alexa Ertmer Institute of Virology, Technical University of Munich, Munich, Germany

Eckhard Flechsig Institute of Virology and Immunobiology, University of Wurzburg, Wurzburg, Germany

Sabine Gilch Institute of Virology, Technical University of Munich, Munich, Germany

Peter Riederer Clinical Neurochemistry and NPF Center of Excellence, Clinic of Psychiatry and Psychotherapy, University of Wurzburg, Wurzburg, Germany

Manfred Gerlach Clinic of Child and Adolescent Psychiatry and Psychotherapy, University of Wurzburg, Wurzburg, Germany

Hermann M Schätzl Institute of Virology, Technical University of Munich, Munich, Germany

Michael A Klein Institute of Virology and Immunobiology, University of Wurzburg, Wurzburg, Germany

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Kyu Hwan Shim, Niti Sharma & Seong Soo A An. (2022) Prion therapeutics: Lessons from the past. Prion 16:1, pages 265-294.
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Soshi Kanemoto. (2015) Targeting the endoplasmic reticulum in prion disease treatment: breakthroughs and challenges. Research and Reports in Biochemistry 5, pages 31-38.
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Sabine Gilch, Carmen Krammer & Hermann M Schätzl. (2008) Targeting prion proteins in neurodegenerative disease. Expert Opinion on Biological Therapy 8:7, pages 923-940.
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Suehiro Sakaguchi. (2008) Recent developments in therapeutics for prion diseases. Expert Opinion on Therapeutic Patents 18:1, pages 35-59.
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The tyrosine kinase inhibitor imatinib mesylate delays prion neuroinvasion by inhibiting prion propagation in the periphery

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The tyrosine kinase inhibitor imatinib mesylate delays prion neuroinvasion by inhibiting prion propagation in the periphery

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