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Review Article

Use of medicinal doses of zinc as a safe and efficient coadjutant in the treatment of male hypogonadism

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Pages 669-678 | Received 17 Nov 2018, Accepted 27 Dec 2018, Published online: 15 Feb 2019

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E. E. Besong, P. J. Ashonibare, O. O. Obembe, M. A. Folawiyo, D. H. Adeyemi, M. A. Hamed, T. M. Akhigbe & R. E. Akhigbe. (2023) Zinc protects against lead-induced testicular damage via modulation of steroidogenic and xanthine oxidase/uric acid/caspase 3-mediated apoptotic signaling in male Wistar rats. The Aging Male 26:1.
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R. E. Akhigbe, M. A. Hamed, A. F. Odetayo, T. M. Akhigbe & P. A. Oyedokun. (2023) Zinc improves sexual and erectile function in HAART-treated rats via the upregulation of erectogenic enzymes and maintenance of redox balance. The Aging Male 26:1.
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Kamil Gill, Joanna Jakubik-Uljasz, Aleksandra Rosiak-Gill, Marta Grabowska, Marcin Matuszewski & Malgorzata Piasecka. (2020) Male aging as a causative factor of detrimental changes in human conventional semen parameters and sperm DNA integrity. The Aging Male 23:5, pages 1321-1332.
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Michał Wrzosek, Jakub Woźniak & Dariusz Włodarek. (2020) The causes of adverse changes of testosterone levels in men. Expert Review of Endocrinology & Metabolism 15:5, pages 355-362.
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Heitor O Santos. (2022) Therapeutic supplementation with zinc in the management of COVID-19–related diarrhea and ageusia/dysgeusia: mechanisms and clues for a personalized dosage regimen. Nutrition Reviews 80:5, pages 1086-1093.
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Amit Zamir, Tavor Ben-Zeev & Jay R. Hoffman. (2021) Manipulation of Dietary Intake on Changes in Circulating Testosterone Concentrations. Nutrients 13:10, pages 3375.
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José Manuel Pérez de la Lastra, Celia Andrés-Juan, Francisco J. Plou & Eduardo Pérez-Lebeña. (2021) Theoretical Three-Dimensional Zinc Complexes with Glutathione, Amino Acids and Flavonoids. Stresses 1:3, pages 123-141.
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Juntao Zhang, Chao Zhang, Aifeng Liu, Qiang Ji, Lixia Ren, Chuanrui Ma, Hengyu Zhang, Chaochao Wu, Donglin Zhang, Man Shang & Feng He. (2021) Synthesis of Icariin-Zinc and its Protective Effect on Exercise Fatigue and Reproductive System Related Glands in Male Rats. Frontiers in Pharmacology 12.
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Heitor O. Santos, Grant M. Tinsley, Guilherme A. R. da Silva & Allain A. Bueno. (2020) Pharmaconutrition in the Clinical Management of COVID-19: A Lack of Evidence-Based Research But Clues to Personalized Prescription. Journal of Personalized Medicine 10:4, pages 145.
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Heitor O. Santos, Scott Howell, Keith Nichols & Filipe J. Teixeira. (2020) Reviewing the Evidence on Vitamin D Supplementation in the Management of Testosterone Status and Its Effects on Male Reproductive System (Testis and Prostate): Mechanistically Dazzling but Clinically Disappointing. Clinical Therapeutics 42:6, pages e101-e114.
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Heitor O. Santos, Filipe J. Teixeira & Brad J. Schoenfeld. (2020) Dietary vs. pharmacological doses of zinc: A clinical review. Clinical Nutrition 39:5, pages 1345-1353.
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