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Original Article

Estrogen: effects on normal brain function and neuropsychiatric disorders

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Pages 97-104 | Published online: 03 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Peter Chedraui, Glenda San Miguel & Gino Schwager. (2011) The effect of soy-derived isoflavones over hot flushes, menopausal symptoms and mood in climacteric women with increased body mass index. Gynecological Endocrinology 27:5, pages 307-313.
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Yan Hou, Xiu-Qi Bao, Huai-Ling Wei, Yuan Luo & Geng-Tao Liu. (2011) Long-term deprivation of gonadal hormone accelerates brain aging in mice. Neurological Research 33:1, pages 43-49.
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Antonella Gasbarri, Assunta Pompili, Maria Clotilde Tavares & Carlos Tomaz. (2009) Estrogen and cognitive functions. Expert Review of Endocrinology & Metabolism 4:5, pages 507-520.
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Articles from other publishers (34)

Xiao-Qian Ren, Xin Huang, Shu-Yun Xing, Yan Long, Dan-Hua Yuan, Hao Hong & Su-Su Tang. (2023) Neuroprotective effects of novel compound FMDB on cognition, neurogenesis and apoptosis in APP/PS1 transgenic mouse model of Alzheimer's disease. Neurochemistry International 165, pages 105510.
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Tianyao Shi, Shufang Feng, Zhonglin Zhou, Fengan Li, Yuan Fu & Wenxia Zhou. (2023) Stress-altering anterior insular cortex activity affects risk decision-making behavior in mice of different sexes. Frontiers in Cellular Neuroscience 17.
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Emily N. Hilz & Hongjoo J. Lee. (2023) Estradiol and progesterone in female reward-learning, addiction, and therapeutic interventions. Frontiers in Neuroendocrinology 68, pages 101043.
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Irina Trofimova. (2022) Analytic Background in the Neuroscience of the Potential Project “Hippocrates”. Brain Sciences 13:1, pages 39.
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Brigitte Leeners, Tillmann Krüger, Kirsten Geraedts, Enrico Tronci, Toni Mancini, Fabian Ille, Marcel Egli, Susanna Röblitz, Dorothea Wunder, Lanja Saleh, Cordula Schippert & Michael P. Hengartner. (2021) Cognitive function in association with high estradiol levels resulting from fertility treatment. Hormones and Behavior 130, pages 104951.
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Javad Anjom-Shoae, Omid Sadeghi, Ammar Hassanzadeh Keshteli, Hamid Afshar, Ahmad Esmaillzadeh & Peyman Adibi. (2020) Legume and nut consumption in relation to depression, anxiety and psychological distress in Iranian adults. European Journal of Nutrition 59:8, pages 3635-3645.
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Ashvini Vengadavaradan & Karthick Subramanian. (2020) Surges and dips of estrogen: A case of Catamenial epilepsy with post-hysterectomy psychosis. Asian Journal of Psychiatry 53, pages 102372.
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Yufei Cui, Cong Huang, Haruki Momma, Kaijun Niu & Ryoichi Nagatomi. (2020) Daily dietary isoflavone intake in relation to lowered risk of depressive symptoms among men. Journal of Affective Disorders 261, pages 121-125.
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Kuan Liao, Yeqing Gu, Mingyue Liu, Jingzhu Fu, Xiaotong Wang, Guanlin Yang, Qing Zhang, Li Liu, Ge Meng, Zhanxin Yao, Hongmei Wu, Yang Xia, Xue Bao, Shunming Zhang, Shaomei Sun, Xing Wang, Ming Zhou, Huanli Jiao, Qiyu Jia, Kun Song, Yuntang Wu & Kaijun Niu. (2019) Association of dietary patterns with depressive symptoms in Chinese postmenopausal women. British Journal of Nutrition 122:10, pages 1168-1174.
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Kimberly M. AlbertPaul A. Newhouse. (2019) Estrogen, Stress, and Depression: Cognitive and Biological Interactions. Annual Review of Clinical Psychology 15:1, pages 399-423.
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Jing Wang, Rui Yu, Qiu-Qin Han, Hui-Jie Huang, Ya-Lin Wang, Hao-Yuan Li, Hui-Mei Wang, Xiao-Rong Chen, Shu-Lan Ma & Jin Yu. (2019) G-1 exhibit antidepressant effect, increase of hippocampal ERs expression and improve hippocampal redox status in aged female rats. Behavioural Brain Research 359, pages 845-852.
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Su-Su Tang, Yi Ren, Xiao-Qian Ren, Jing-Ran Cao, Hao Hong, Hui Ji & Qing-Hua Hu. (2019) ERα and/or ERβ activation ameliorates cognitive impairment, neurogenesis and apoptosis in type 2 diabetes mellitus mice. Experimental Neurology 311, pages 33-43.
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Agnė Kadusauskienė & Jonas Čeponis. 2018. Encyclopedia of Endocrine Diseases. Encyclopedia of Endocrine Diseases 751 762 .
Martin Birkhaeuser. 2018. Reproductive Medicine for Clinical Practice. Reproductive Medicine for Clinical Practice 163 175 .
Elseline Hoekzema, Erika Barba-Müller, Cristina Pozzobon, Marisol Picado, Florencio Lucco, David García-García, Juan Carlos Soliva, Adolf Tobeña, Manuel Desco, Eveline A Crone, Agustín Ballesteros, Susanna Carmona & Oscar Vilarroya. (2016) Pregnancy leads to long-lasting changes in human brain structure. Nature Neuroscience 20:2, pages 287-296.
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Crystal Edler Schiller, Sarah L. Johnson, Anna C. Abate, Peter J. Schmidt & David R. Rubinow. 2011. Comprehensive Physiology. Comprehensive Physiology 1135 1160 .
Rena Li, Jie Cui & Yong Shen. (2014) Brain sex matters: Estrogen in cognition and Alzheimer’s disease. Molecular and Cellular Endocrinology 389:1-2, pages 13-21.
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Aline Richard, Sabine Rohrmann, Meichun Mohler-Kuo, Stephanie Rodgers, Rebecca Moffat, Uwe Güth & Monika Eichholzer. (2014) Urinary phytoestrogens and depression in perimenopausal US women: NHANES 2005–2008. Journal of Affective Disorders 156, pages 200-205.
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Assunta Pompili, Benedetto Arnone & Antonella Gasbarri. (2012) Estrogens and memory in physiological and neuropathological conditions. Psychoneuroendocrinology 37:9, pages 1379-1396.
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William Davies. (2012) Does steroid sulfatase deficiency influence postpartum psychosis risk?. Trends in Molecular Medicine 18:5, pages 256-262.
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Joan Pitkin. (2012) Alternative and complementary therapies for the menopause. Menopause International 18:1, pages 20-27.
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Yi Xing, Wei Qin, Fang Li, Xiang-Fei Jia & Jianping Jia. (2012) Apolipoprotein E ε4 Status Modifies the Effects of Sex Hormones on Neuropsychiatric Symptoms of Alzheimer’s Disease. Dementia and Geriatric Cognitive Disorders 33:1, pages 35-42.
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Sarah L. Berga & Yolanda R. Smith. 2012. Handbook of Neuroendocrinology. Handbook of Neuroendocrinology 551 571 .
Pardeep Kumar, Asia Taha, R.K. Kale, S.M. Cowsik & Najma Zaheer Baquer. (2011) Physiological and biochemical effects of 17β estradiol in aging female rat brain. Experimental Gerontology 46:7, pages 597-605.
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Glenda E. Gillies & Simon McArthur. (2010) Estrogen Actions in the Brain and the Basis for Differential Action in Men and Women: A Case for Sex-Specific Medicines. Pharmacological Reviews 62:2, pages 155-198.
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Yan Hou, Huailing Wei, Yuan Luo & Gengtao Liu. (2010) Modulating expression of brain heat shock proteins by estrogen in ovariectomized mice model of aging. Experimental Gerontology 45:5, pages 323-330.
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Miklós Sárvári, Erik Hrabovszky, Imre Kalló, Orsolya Galamb, Norbert Solymosi, István Likó, Béla Molnár, Károly Tihanyi, Zsolt Szombathelyi & Zsolt Liposits. (2010) Gene Expression Profiling Identifies Key Estradiol Targets in the Frontal Cortex of the Rat. Endocrinology 151:3, pages 1161-1176.
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Markus Lipovac, Peter Chedraui, Christine Gruenhut, Ana Gocan, Maria Stammler & Martin Imhof. (2010) Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from red clover extracts. Maturitas 65:3, pages 258-261.
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Glenda E. Gillies & Simon McArthur. (2010) Independent influences of sex steroids of systemic and central origin in a rat model of Parkinson's disease: A contribution to sex-specific neuroprotection by estrogens. Hormones and Behavior 57:1, pages 23-34.
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István M. Ábrahám, Zsombor Kőszegi, Emeline Tolod-Kemp & Éva M. Szegő. (2009) Action of estrogen on survival of basal forebrain cholinergic neurons: Promoting amelioration. Psychoneuroendocrinology 34, pages S104-S112.
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Alejandro Lopez-Tobón, Efraín Cepeda-Prado & Gloria Patricia Cardona-Gómez. (2009) Decrease of Tau Hyperphosphorylation by 17β Estradiol Requires Sphingosine Kinase in a Glutamate Toxicity Model. Neurochemical Research 34:12, pages 2206-2214.
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Miroslava G. Varadinova, Diana I. Docheva-Drenska & Nadka I. Boyadjieva. (2009) Effects of anthocyanins on learning and memory of ovariectomized rats. Menopause 16:2, pages 345-349.
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Ricardo M. Marinho, José Maria SoaresJr.Jr., Ricardo C. Santiago, Carla C. Maganhin, Flavia Machado, Ana Marcia de Miranda Cota & Edmund C. Baracat. (2008) Effects of estradiol on the cognitive function of postmenopausal women. Maturitas 60:3-4, pages 230-234.
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P. Stute & K. Kalkhake. (2008) Chirurgische Menopause und DemenzSurgical menopause and dementia. Gynäkologische Endokrinologie 6:2, pages 129-130.
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