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Original Article

Estrogenic uterovaginal effects of oral estetrol in the modified Allen–Doisy test

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Pages 22-28 | Published online: 03 Jul 2009

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Read on this site (4)

Andrea R. Genazzani, Ulysse Gaspard & Jean-Michel Foidart. (2019) Oral investigational drugs currently in phase I or phase II for the amelioration of menopausal symptoms. Expert Opinion on Investigational Drugs 28:3, pages 235-247.
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H. J. T. Coelingh Bennink, C. Verhoeven, Y. Zimmerman, M. Visser, J-M. Foidart & K. Gemzell-Danielsson. (2017) Pharmacokinetics of the fetal estrogen estetrol in a multiple-rising-dose study in postmenopausal women. Climacteric 20:3, pages 285-289.
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H. J. T. Coelingh Bennink, C. F. Holinka & E. Diczfalusy. (2008) Estetrol review: profile and potential clinical applications. Climacteric 11:sup1, pages 47-58.
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M. Visser, C. F. Holinka & H. J. T. Coelingh Bennink. (2008) First human exposure to exogenous single-dose oral estetrol in early postmenopausal women. Climacteric 11:sup1, pages 31-40.
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Articles from other publishers (19)

Céline Gérard & Jean-Michel Foidart. (2023) Estetrol: From Preclinical to Clinical Pharmacology and Advances in the Understanding of the Molecular Mechanism of Action. Drugs in R&D 23:2, pages 77-92.
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Teresa Navarrete Horta, Francisco Javier Guerrero Carreño, Paulina Valdés Aguerrebere & Leopoldo Alejandro Vázquez Estrada. (2022) Estetrol: ¿un nuevo paradigma en terapia ginecológica?. Acta Médica Grupo Ángeles 20:1, pages 50-57.
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Anne Gallez, Isabelle Dias Da Silva, Vincent Wuidar, Jean-Michel Foidart & Christel Péqueux. (2021) Estetrol and Mammary Gland: Friends or Foes?. Journal of Mammary Gland Biology and Neoplasia 26:3, pages 297-308.
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Marie-Cécile Valéra, Coralie Fontaine, Emmanuelle Noirrit-Esclassan, Pierre Gourdy, Françoise Lenfant & Jean-François Arnal. 2019. La Ménopause en Pratique. La Ménopause en Pratique 157 168 .
Marie-Cécile Valéra, Emmanuelle Noirrit-Esclassan, Marion Dupuis, Coralie Fontaine, Françoise Lenfant, Anne Briaux, Cendrine Cabou, Cedric Garcia, Olivier Lairez, Jean-Michel Foidart, Bernard Payrastre & Jean-François Arnal. (2018) Effect of estetrol, a selective nuclear estrogen receptor modulator, in mouse models of arterial and venous thrombosis. Molecular and Cellular Endocrinology 477, pages 132-139.
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Zhong Ruihua, Xie Shuwu, Li Guoting, Yang Wenjie, Guo Xiangjie, Li Zhao, Zhou Jieyun, Ma Aying & Zhu Yan. (2018) Hormone-like activities of Kuntai capsule in the uteri of ovariectomized rats and immature rabbits. Journal of Traditional Chinese Medicine 38:6, pages 853-861.
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Marie-Cécile Valéra, Coralie Fontaine, Marion Dupuis, Emmanuelle Noirrit-Esclassan, Alexia Vinel, Maeva Guillaume, Pierre Gourdy, Françoise Lenfant & Jean-François Arnal. (2018) Towards optimization of estrogen receptor modulation in medicine. Pharmacology & Therapeutics 189, pages 123-129.
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Thibaut Benoit, Marie-Cecile Valera, Coralie Fontaine, Melissa Buscato, Francoise Lenfant, Isabelle Raymond-Letron, Florence Tremollieres, Michel Soulie, Jean-Michel Foidart, Xavier Game & Jean-Francois Arnal. (2017) Estetrol, a Fetal Selective Estrogen Receptor Modulator, Acts on the Vagina of Mice through Nuclear Estrogen Receptor α Activation. The American Journal of Pathology 187:11, pages 2499-2507.
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Herjan J.T. Coelingh Bennink, Carole Verhoeven, Yvette Zimmerman, Monique Visser, Jean-Michel Foidart & Kristina Gemzell-Danielsson. (2017) Pharmacodynamic effects of the fetal estrogen estetrol in postmenopausal women: results from a multiple-rising-dose study. Menopause 24:6, pages 677-685.
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Herjan J.T. Coelingh Bennink, Carole Verhoeven, Yvette Zimmerman, Monique Visser, Jean-Michel Foidart & Kristina Gemzell-Danielsson. (2016) Clinical effects of the fetal estrogen estetrol in a multiple-rising-dose study in postmenopausal women. Maturitas 91, pages 93-100.
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Maria Magdalena Montt-Guevara, Maria Silvia Giretti, Eleonora Russo, Andrea Giannini, Paolo Mannella, Andrea Riccardo Genazzani, Alessandro David Genazzani & Tommaso Simoncini. (2015) Estetrol Modulates Endothelial Nitric Oxide Synthesis in Human Endothelial Cells. Frontiers in Endocrinology 6.
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N. Pluchino, P. Drakopoulos, E. Casarosa, L. Freschi, P. Petignat, M. Yaron & A.R. Genazzani. (2015) Effect of estetrol on Beta-Endorphin level in female rats. Steroids 95, pages 104-110.
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C. F. Singer, H. J. T. C. Bennink, C. Natter, S. Steurer, M. Rudas, F. Moinfar, N. Appels, M. Visser & E. Kubista. (2014) Antiestrogenic effects of the fetal estrogen estetrol in women with estrogen-receptor positive early breast cancer. Carcinogenesis 35:11, pages 2447-2451.
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N. Pluchino, A.N. Santoro, E. Casarosa, A. Giannini, A. Genazzani, M. Russo, N. Russo, P. Petignat & A.R. Genazzani. (2014) Effect of estetrol administration on brain and serum allopregnanolone in intact and ovariectomized rats. The Journal of Steroid Biochemistry and Molecular Biology 143, pages 285-290.
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Maria Silvia Giretti, Maria Magdalena Montt Guevara, Elena Cecchi, Paolo Mannella, Giulia Palla, Stefania Spina, Guja Bernacchi, Silvia Di Bello, Andrea Riccardo Genazzani, Alessandro D. Genazzani & Tommaso Simoncini. (2014) Effects of Estetrol on Migration and Invasion in T47-D Breast Cancer Cells through the Actin Cytoskeleton. Frontiers in Endocrinology 5.
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Rob H P Hilgers, Suzanne Oparil, Wout Wouters & Herjan J T Coelingh Bennink. (2012) Vasorelaxing effects of estetrol in rat arteries. Journal of Endocrinology 215:1, pages 97-106.
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. (2009) Current World Literature. Current Opinion in Obstetrics & Gynecology 21:5, pages 450-455.
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Monique Visser & Herjan J.T. Coelingh Bennink. (2009) Clinical applications for estetrol. The Journal of Steroid Biochemistry and Molecular Biology 114:1-2, pages 85-89.
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Herjan J.T. Coelingh Bennink, Sven Skouby, Philippe Bouchard & Christian F. Holinka. (2008) Ovulation inhibition by estetrol in an in vivo model. Contraception 77:3, pages 186-190.
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