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Pharmaceutical Biology Volume 59, 2021 - Issue 1
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Research Article

Astragalus polysacharin inhibits hepatocellular carcinoma-like phenotypes in a murine HCC model through repression of M2 polarization of tumour-associated macrophages

Chun Lia Department of Doppler Ultrasonic Medicine, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
,
Xin-You Panb Combined Department of Traditional Chinese Medicine and West Medicine, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
,
Mingyun Mab Combined Department of Traditional Chinese Medicine and West Medicine, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
,
Jun Zhaoc Department of Rheumatism Immunology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
,
Fengda Zhaob Combined Department of Traditional Chinese Medicine and West Medicine, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
&
Ya-Ping Lvb Combined Department of Traditional Chinese Medicine and West Medicine, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, ChinaCorrespondence[email protected]
Pages 1531-1537 | Received 08 May 2021, Accepted 04 Oct 2021, Published online: 02 Nov 2021

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Zedong Chen, Huiyu Liang, Xianxin Yan, Qiuer Liang, Zhenyu Bai, Ting Xie, Jiaojiao Dai, Xiaoshan Zhao & Ya Xiao. (2023) Astragalus polysaccharide promotes autophagy and alleviates diabetic nephropathy by targeting the lncRNA Gm41268/PRLR pathway. Renal Failure 45:2.
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Articles from other publishers (11)

Hsiang-Chun Lai, Ju-Chien Cheng, Hei-Tung Yip, Long-Bin Jeng & Sheng-Teng Huang. (2024) Chinese herbal medicine decreases incidence of hepatocellular carcinoma in diabetes mellitus patients with regular insulin management. World Journal of Gastrointestinal Oncology 16:3, pages 716-731.
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Qian Yang, Dandan Meng, Qinyuan Zhang & Jin Wang. (2024) Advances in research on the anti-tumor mechanism of Astragalus polysaccharides. Frontiers in Oncology 14.
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Yang Liu, Jiawen Wu & Huiqin Hao. (2024) Antitumor immunostimulatory activity of the traditional Chinese medicine polysaccharide on hepatocellular carcinoma. Frontiers in Immunology 15.
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Xinyi Zhang, Chao Yu, Siqi Zhao, Min Wang, Longcheng Shang, Jin Zhou & Yong Ma. (2023) The role of tumor‐associated macrophages in hepatocellular carcinoma progression: A narrative review. Cancer Medicine 12:24, pages 22109-22129.
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Yi Yuan, Dailin Wu, Jing Li, Dan Huang, Yan Zhao, Tianqi Gao, Zhenjie Zhuang, Ying Cui, Da-Yong Zheng & Ying Tang. (2023) Mechanisms of tumor-associated macrophages affecting the progression of hepatocellular carcinoma. Frontiers in Pharmacology 14.
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Dan Liang, Lu Liu, Yunjie Zhao, Zhenyi Luo, Yadi He, Yanping Li, Shiyun Tang, Jianyuan Tang & Nianzhi Chen. (2023) Targeting extracellular matrix through phytochemicals: a promising approach of multi-step actions on the treatment and prevention of cancer. Frontiers in Pharmacology 14.
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Liping Ren, Xianrun Pan, Lin Ning, Di Gong, Jian Huang, Kejun Deng, Lei Xie & Yang Zhang. (2023) Construction of a Combined Hypoxia-related Genes Model for Hepatocellular Carcinoma Prognosis. Current Computer-Aided Drug Design 19:2, pages 150-161.
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Mingzhe Li, Fangfang Duan, Zhiqiang Pan, Xiaomei Liu, Wenli Lu, Chao Liang, Zhaoqin Fang, Peike Peng & Dongwei Jia. (2023) Astragalus Polysaccharide Promotes Doxorubicin-Induced Apoptosis by Reducing O-GlcNAcylation in Hepatocellular Carcinoma. Cells 12:6, pages 866.
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Yunheng Li, Hui Li, Qiaojun He & Xiaochun Yang. (2022) Potential of Compounds Originating from the Nature to Act in Hepatocellular Carcinoma Therapy by Targeting the Tumor Immunosuppressive Microenvironment: A Review. Molecules 28:1, pages 195.
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Yuefeng Chen, Xinnan Pan, Baoming Tian & Yajun Hu. (2022) Polysaccharide immunization and colorectal cancer: A systematic review and network meta-analysis. Frontiers in Nutrition 9.
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Yushen Huang, Wen Luo, Siyun Chen, Hongmei Su, Wuchang Zhu, Yuanyuan Wei, Yue Qiu, Yan Long, Yanxia Shi & Jinbin Wei. (2022) Association of a Novel DOCK2 Mutation-Related Gene Signature With Immune in Hepatocellular Carcinoma. Frontiers in Genetics 13.
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