Advanced search
Publication Cover
Expert Opinion on Pharmacotherapy Volume 20, 2019 - Issue 11
Submit an article Journal homepage
5,356
Views
26
CrossRef citations to date
0
Altmetric
Original Research

Efficacy of istradefylline for gait disorders with freezing of gait in Parkinson’s disease: A single-arm, open-label, prospective, multicenter study

Mutsumi IijimaDepartment of Neurology, Tokyo Women’s Medical University, Tokyo, JapanCorrespondence[email protected]
View further author information
,
Satoshi OrimoDepartment of Neurology, Kanto Central Hospital, Tokyo, JapanView further author information
,
Hiroo TerashiDepartment of Neurology, Tokyo Medical University, Tokyo, JapanView further author information
,
Masahiko SuzukiDepartment of Neurology, Katsushika Medical Center, The Jikei University School of Medicine, Tokyo, JapanView further author information
,
Akito HayashiDepartment of Rehabilitation, Juntendo University Urayasu Hospital, Urayasu, JapanView further author information
,
Hideki ShimuraDepartment of Neurology, Juntendo University Urayasu Hospital, Urayasu, JapanView further author information
,
Hiroshi MitomaDepartment of Medical Education, Tokyo Medical University, Tokyo, JapanView further author information
,
Kazuo KitagawaDepartment of Neurology, Tokyo Women’s Medical University, Tokyo, JapanView further author information
&
Yasuyuki OkumaDepartment of Neurology, Juntendo University Shizuoka Hospital, Izunokuni, JapanView further author information
 show all
Pages 1405-1411 | Received 01 Mar 2019, Accepted 29 Apr 2019, Published online: 28 May 2019

Citations (26)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Stuart H Isaacson, Sagari Betté & Rajesh Pahwa. (2022) Istradefylline for OFF Episodes in Parkinson’s Disease: A US Perspective of Common Clinical Scenarios. Degenerative Neurological and Neuromuscular Disease 12, pages 97-109.
Read now
Matthew D Smith, Danielle E Brazier & Emily J Henderson. (2021) Current Perspectives on the Assessment and Management of Gait Disorders in Parkinson’s Disease. Neuropsychiatric Disease and Treatment 17, pages 2965-2985.
Read now
Peter Jenner, Akihisa Mori, Stephen D. Aradi & Robert A. Hauser. (2021) Istradefylline – a first generation adenosine A2A antagonist for the treatment of Parkinson’s disease. Expert Review of Neurotherapeutics 21:3, pages 317-333.
Read now
Martijn L.T.M. Müller, Uros Marusic, Miriam van Emde Boas, Daniel Weiss & Nicolaas I. Bohnen. (2019) Treatment options for postural instability and gait difficulties in Parkinson’s disease. Expert Review of Neurotherapeutics 19:12, pages 1229-1251.
Read now

Articles from other publishers (22)

Xiao-Zhong Jing, Xiang-Zhen Yuan, Xingguang Luo, Shu-Yun Zhang & Xiao-Ping Wang. (2023) An Update on Nondopaminergic Treatments for Motor and Non-motor Symptoms of Parkinson’s Disease. Current Neuropharmacology 21:8, pages 1806-1826.
Crossref
Yasar Torres-Yaghi, Nobutaka Hattori, Olivier Rascol, Yu Nakajima, Shelby M. King, Akihisa Mori & Fernando Pagan. (2023) Istradefylline effects on tremor dominance (TD) and postural instability and gait difficulty (PIGD). Clinical Parkinsonism & Related Disorders 9, pages 100224.
Crossref
Rahul & Yasir Siddique. (2022) Neurodegenerative Disorders and the Current State, Pathophysiology, and Management of Parkinson’s Disease. CNS & Neurological Disorders - Drug Targets 21:7, pages 574-595.
Crossref
Melissa Talita Wiprich, Stefani Altenhofen, Darlan Gusso, Rafaela da Rosa Vasques, Rodrigo Zanandrea, Luiza Wilges Kist, Mauricio Reis Bogo & Carla Denise Bonan. (2022) Modulation of adenosine signaling reverses 3-nitropropionic acid-induced bradykinesia and memory impairment in adult zebrafish. Progress in Neuro-Psychopharmacology and Biological Psychiatry, pages 110602.
Crossref
Daniel Garbin Di Luca, Nikolai Gil D. Reyes & Susan H. Fox. (2022) Newly Approved and Investigational Drugs for Motor Symptom Control in Parkinson's Disease. Drugs 82:10, pages 1027-1053.
Crossref
Masahiro Nomoto, Takayuki Ishida, Michinori Koebis, Takanori Kamei, Ippei Suzuki, Nobutaka Hattori & Yoshio Tsuboi. (2022) Characteristics of wearing-off and motor symptoms improved by safinamide adjunct therapy in patients with Parkinson's disease: A post hoc analysis of a Japanese phase 2/3 study. Journal of the Neurological Sciences 434, pages 120083.
Crossref
Makio Takahashi, Toshio Shimokawa, Jinsoo Koh, Takao Takeshima, Hirofumi Yamashita, Yoshinori Kajimoto, Akihisa Mori & Hidefumi Ito. (2022) Efficacy and safety of istradefylline in patients with Parkinson's disease presenting with postural abnormalities: Results from a multicenter, prospective, and open-label exploratory study in Japan. Journal of the Neurological Sciences 432, pages 120078.
Crossref
Lan Luo. 2022. Encyclopedia of Behavioral Neuroscience, 2nd edition. Encyclopedia of Behavioral Neuroscience, 2nd edition 313 317 .
Renyan Ma, Yuning Hou, Yiyin Zhang, Muyang He, Song Gao, Keneilwe Kenny Kaudimba, Kaiqing Lin, Lingjing Jin, Tiemin Liu & Ru Wang. (2021) The Efficacy of Tai Chi and Stretching Exercises Based on a Smartphone Application for Patients With Parkinson's Disease: A Protocol for a Randomized Controlled Trial. Frontiers in Neurology 12.
Crossref
Yifei Feng & Yan Lu. (2021) Immunomodulatory Effects of Dopamine in Inflammatory Diseases. Frontiers in Immunology 12.
Crossref
Bhupesh Vaidya, Kritika Dhamija, Priyanka Guru & Shyam Sunder Sharma. (2021) Parkinson's disease in women: Mechanisms underlying sex differences. European Journal of Pharmacology 895, pages 173862.
Crossref
Kavya Prasad, Erik F. J. de Vries, Philip H. Elsinga, Rudi A. J. O. Dierckx & Aren van Waarde. (2021) Allosteric Interactions between Adenosine A2A and Dopamine D2 Receptors in Heteromeric Complexes: Biochemical and Pharmacological Characteristics, and Opportunities for PET Imaging. International Journal of Molecular Sciences 22:4, pages 1719.
Crossref
Juan Segura-Aguilar. 2021. Clinical Studies and Therapies in Parkinson's Disease. Clinical Studies and Therapies in Parkinson's Disease 173 185 .
Amnon A. Berger, Ariel Winnick, Alexandra Welschmeyer, Alicia Kaneb, Kevin Berardino, Elyse M. Cornett, Alan D. Kaye, Omar Viswanath & Ivan Urits. (2020) Istradefylline to Treat Patients with Parkinson’s Disease Experiencing “Off” Episodes: A Comprehensive Review. Neurology International 12:3, pages 109-129.
Crossref
Chao Gao, Jun Liu, Yuyan Tan & Shengdi Chen. (2020) Freezing of gait in Parkinson’s disease: pathophysiology, risk factors and treatments. Translational Neurodegeneration 9:1.
Crossref
Akihisa Mori. (2020) How do adenosine A2A receptors regulate motor function?. Parkinsonism & Related Disorders 80, pages S13-S20.
Crossref
Peter A. LeWitt & K. Ray Chaudhuri. (2020) Unmet needs in Parkinson disease: Motor and non-motor. Parkinsonism & Related Disorders 80, pages S7-S12.
Crossref
Paulina Gonzalez-Latapi, Suvorit Subhas Bhowmick, Gerard Saranza & Susan H. Fox. (2020) Non-Dopaminergic Treatments for Motor Control in Parkinson’s Disease: An Update. CNS Drugs 34:10, pages 1025-1044.
Crossref
Jiang-Fan Chen & Rodrigo A. Cunha. (2020) The belated US FDA approval of the adenosine A2A receptor antagonist istradefylline for treatment of Parkinson’s disease. Purinergic Signalling 16:2, pages 167-174.
Crossref
Femke Hulzinga, Alice Nieuwboer, Bauke W. Dijkstra, Martina Mancini, Carolien Strouwen, Bastiaan R. Bloem & Pieter Ginis. (2020) The New Freezing of Gait Questionnaire: Unsuitable as an Outcome in Clinical Trials?. Movement Disorders Clinical Practice 7:2, pages 199-205.
Crossref
Diego Guidolin, Manuela Marcoli, Cinzia Tortorella, Guido Maura & Luigi F. Agnati. 2020. Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors. Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors 247 277 .
Pran Kishore Deb, Sarah Falah Kokaz, Sara Nidal Abed, Balakumar Chandrasekaran, Wafa Hourani, Abdulmuttaleb Yousef Jaber, Raghu Prasad Mailavaram, Puneet Kumar & Katharigatta N. Venugopala. 2020. Frontiers in Pharmacology of Neurotransmitters. Frontiers in Pharmacology of Neurotransmitters 325 359 .

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.