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Amyotrophic Lateral Sclerosis Volume 6, 2005 - Issue 3
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SHORT REPORT

Valproate and HDAC Inhibition: A new epigenetic strategy to mitigate phenotypic severity in ALS?

L. Tremolizzo Department of Neurology, S. Gerardo Hospital; Department of Neuroscience, University of Milano‐Bicocca, Monza, Italy
,
V. Rodriguez‐Menendez Department of Neuroscience, University of Milano‐Bicocca, Monza, Italy
,
G. Sala Department of Neuroscience, University of Milano‐Bicocca, Monza, Italy
,
J. C. Di Francesco Department of Neuroscience, University of Milano‐Bicocca, Monza, Italy
&
C. Ferrarese Department of Neurology, S. Gerardo Hospital; Department of Neuroscience, University of Milano‐Bicocca, Monza, ItalyCorrespondence[email protected]
Pages 185-186 | Received 03 Feb 2005, Accepted 03 Feb 2005, Published online: 10 Jul 2009

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Lucio Tremolizzo, Paolo Messina, Elisa Conti, Gessica Sala, Matteo Cecchi, Luisa Airoldi, Roberta Pastorelli, Elisabetta Pupillo, Monica Bandettini Di Poggio, Massimiliano Filosto, Christian Lunetta, Cristina Agliardi, Franca Guerini, Jessica Mandrioli, Andrea Calvo, Ettore Beghi, Carlo Ferrarese, M.S. Cotelli, M. Corbo, E. Maestri, E. Georgoulopoulou, L. Marzorati, E. Susani, A. Arosio, A. Chiò, G. Fuda & F. Pisa. (2014) Whole-blood global DNA methylation is increased in amyotrophic lateral sclerosis independently of age of onset. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 15:1-2, pages 98-105.
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Yajie Wang, Yan-Ling Zhang, Krista Hennig, Jennifer P. Gale, Yijia Hong, Anna Cha, Misha Riley, Florence Wagner, Stephen J. Haggarty, Edward Holson & Jacob Hooker. (2013) Class I HDAC imaging using [3H]CI-994 autoradiography. Epigenetics 8:7, pages 756-764.
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Articles from other publishers (5)

Lucio Tremolizzo, Gessica Sala, Elisa Conti, Virginia Rodriguez-Menendez, Antonella Fogli, Angela Michelucci, Paolo Simi, Silvana Penco, Christian Lunetta, Massimo Corbo & Carlo Ferrarese. (2014) Valproate Treatment in an ALS Patient Carrying a c.194G>A Spastin Mutation and SMN2 Homozygous Deletion. Case Reports in Neurological Medicine 2014, pages 1-7.
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Rodrigo Machado-Vieira, Lobna Ibrahim & Carlos A. Zarate Jr.. (2011) Histone Deacetylases and Mood Disorders: Epigenetic Programming in Gene-Environment Interactions. CNS Neuroscience & Therapeutics 17:6, pages 699-704.
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Wenbo Zhou, Kathryn Bercury, Jessica Cummiskey, Nancy Luong, Jacob Lebin & Curt R. Freed. (2011) Phenylbutyrate Up-regulates the DJ-1 Protein and Protects Neurons in Cell Culture and in Animal Models of Parkinson Disease. Journal of Biological Chemistry 286:17, pages 14941-14951.
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Claudia Colussi, Barbara Illi, Jessica Rosati, Francesco Spallotta, Antonella Farsetti, Annalisa Grasselli, Antonello Mai, Maurizio C. Capogrossi & Carlo Gaetano. (2010) Histone deacetylase inhibitors: Keeping momentum for neuromuscular and cardiovascular diseases treatment. Pharmacological Research 62:1, pages 3-10.
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Elsa Raibon, Lisa Marie Todd & Thomas Möller. (2008) Glial Cells in ALS: The Missing Link?. Physical Medicine and Rehabilitation Clinics of North America 19:3, pages 441-459.
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