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Chunlei Zhang, Weijun Zhang, Han Cui, Bin Zhang, Pengcheng Miao, Qi Yang, Mei Bai, Hongmei Jiao & Dehui Chang. (2022) Role of Hub Genes in the Occurrence and Development of Testicular Cancer Based on Bioinformatics. International Journal of General Medicine 15, pages 645-660.
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Mingjiang Li, Bo Yang, Xiaoping Li, Haixia Ren, Liang Zhang, Lei Li, Wei Li, Xuhui Wang, Honggang Zhou & Weidong Zhang. (2021) Identification of Prognostic Factors Related to Super Enhancer-Regulated ceRNA Network in Metastatic Lung Adenocarcinoma. International Journal of General Medicine 14, pages 6261-6275.
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KL Thu, I Soria-Bretones, TW Mak & DW Cescon. (2018) Targeting the cell cycle in breast cancer: towards the next phase. Cell Cycle 17:15, pages 1871-1885.
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Articles from other publishers (41)
Gioia Quarantani, Anna Sorgente, Massimo Alfano, Giovanni Battista Pipitone, Luca Boeri, Edoardo Pozzi, Federico Belladelli, Filippo Pederzoli, Anna Maria Ferrara, Francesco Montorsi, Anna Moles, Paola Carrera, Andrea Salonia & Giorgio Casari. (2023) Whole exome data prioritization unveils the hidden weight of Mendelian causes of male infertility. A report from the first Italian cohort. PLOS ONE 18:8, pages e0288336.
Crossref
Crossref
Sachin Puri, Siddhi Sawant & Kapil Juvale. (2023) A comprehensive review on the indazole based derivatives as targeted anticancer agents. Journal of Molecular Structure 1284, pages 135327.
Crossref
Crossref
Yin Sun, Yanli Xue, Pengkun Sun, Shuyi Mu, Hongbing Liu, Yu Sun, Lin Wang, Jingkai Wang, Tianxiao Wu, Wenbo Yin, Qiaohua Qin, Yixiang Sun, Nian Liu, Hanxun Wang, Huali Yang, Dongmei Zhao & Maosheng Cheng. (2023)
Discovery of the First Potent, Selective, and
In Vivo
Efficacious Polo-like Kinase 4 Proteolysis Targeting Chimera Degrader for the Treatment of
TRIM37
-Amplified Breast Cancer
. Journal of Medicinal Chemistry 66:12, pages 8200-8221.
Crossref
Crossref
Junfang Xu & Liping Zhao. (2023) Polo-like Kinase 4: the Variation During Therapy and its Relation to Treatment Response and Prognostic Risk Stratification in Childhood Acute Lymphoblastic Leukemia Patients. Journal of Pediatric Hematology/Oncology 45:4, pages 189-194.
Crossref
Crossref
Jingxian Li, Yuanjiong Qi, Bo Li, Yan Liu, Kuo Yang, Zhihong Zhang, Jianqiang Zhu & E. Du. (2023) STIL/AURKA axis promotes cell proliferation by influencing primary cilia formation in bladder cancer. Journal of Translational Medicine 21:1.
Crossref
Crossref
Aneta Szudy-Szczyrek, Radosław Mlak, Marcin Mazurek, Tomasz Krajka, Sylwia Chocholska, Paulina Bitkowska, Marta Jutrzenka, Michał Szczyrek, Iwona Homa-Mlak, Andrzej Krajka, Teresa Małecka-Massalska & Marek Hus. (2023) The TT Genotype of the KIAA1524 rs2278911 Polymorphism Is Associated with Poor Prognosis in Multiple Myeloma. Cells 12:7, pages 1029.
Crossref
Crossref
Farhat Firdous, Hadeeqa Gull Raza, Ghayoor Abbas Chotana, M. Iqbal Choudhary, Amir FaisalRahman Shah Zaib Saleem. (2023) Centrosome Clustering & Chemotherapy. Mini-Reviews in Medicinal Chemistry 23:4, pages 429-451.
Crossref
Crossref
Yin Sun, Yanli Xue, Hongbing Liu, Shuyi Mu, Pengkun Sun, Yu Sun, Lin Wang, Hanxun Wang, Jingkai Wang, Tianxiao Wu, Wenbo Yin, Qiaohua Qin, Yixiang Sun, Huali Yang, Dongmei Zhao & Maosheng Cheng. (2023) Discovery of CZS-241: A Potent, Selective, and Orally Available Polo-Like Kinase 4 Inhibitor for the Treatment of Chronic Myeloid Leukemia. Journal of Medicinal Chemistry 66:4, pages 2396-2421.
Crossref
Crossref
Jiaxing Sun, Darrell Belke, Yu Gui, Yong-Xiang Chen, Shenghua Zhou & Xi-Long Zheng. (2023) Polo-like kinase 4 inhibitor CFI-400945 inhibits carotid arterial neointima formation but increases atherosclerosis. Cell Death Discovery 9:1.
Crossref
Crossref
Yang Shu, Yajing Liu, Shirong Bian, Zhouling Xie & Chenzhong Liao. (2023) Discovery of Polo-like Kinase 4 Inhibitors for the Treatment of Cancer:
A Mini Patent Review. Mini-Reviews in Medicinal Chemistry 23:1, pages 67-79.
Crossref
Crossref
Chenggang Zhang, Xianxiong Ma, Guanxin Wei, Xiuxian Zhu, Peng Hu, Xiang Chen, Dianshi Wang, Yuan Li, Tuo Ruan, Weikang Zhang, Kaixiong Tao & Chuanqing Wu. (2023) Centrosomal protein 120 promotes centrosome amplification and gastric cancer progression via USP54-mediated deubiquitination of PLK4. iScience 26:1, pages 105745.
Crossref
Crossref
Manzoor Ahmad Mir, Shariqa Aisha, Kaneez Fatima & Fayaz Ahmad Malik. 2023. Therapeutic potential of Cell Cycle Kinases in Breast Cancer. Therapeutic potential of Cell Cycle Kinases in Breast Cancer
335
353
.
Xiaoyang Zhang, Zesheng Li, Cheng Wei, Lin Luo, Shenghui Li, Junhu Zhou, Hao Liang, Ying Li & Lei Han. (2022) PLK4 initiates crosstalk between cell cycle, cell proliferation and macrophages infiltration in gliomas. Frontiers in Oncology 12.
Crossref
Crossref
Yin Sun, Lin Wang, Yu Sun, Jingkai Wang, Yanli Xue, Tianxiao Wu, Wenbo Yin, Qiaohua Qin, Yixiang Sun, Hanxun Wang, Yinli Gao, Huali Yang, Dongmei Zhao & Maosheng Cheng. (2022) Structure-based discovery of 1-(3-fluoro-5-(5-(3-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)phenyl)-3-(pyrimidin-5-yl)urea as a potent and selective nanomolar type-II PLK4 inhibitor. European Journal of Medicinal Chemistry 243, pages 114714.
Crossref
Crossref
Xing-Ru Mu, Meng-Meng Ma, Zi-Yi Lu, Jun Liu, Yu-Tong Xue, Jiang Cao, Ling-Yu Zeng, Feng Li, Kai-Lin Xu & Qing-Yun Wu. (2022) Effects of the PLK4 inhibitor Centrinone on the biological behaviors of acute myeloid leukemia cell lines. Frontiers in Genetics 13.
Crossref
Crossref
Yin Sun, Yu Sun, Lin Wang, Tianxiao Wu, Wenbo Yin, Jingkai Wang, Yanli Xue, Qiaohua Qin, Yixiang Sun, Huali Yang, Dongmei Zhao & Maosheng Cheng. (2022) Design, synthesis, and biological evaluation of novel pyrazolo [3,4-d]pyrimidine derivatives as potent PLK4 inhibitors for the treatment of TRIM37-amplified breast cancer. European Journal of Medicinal Chemistry 238, pages 114424.
Crossref
Crossref
Mingzheng Hu, Yijie Wang & Jun Zhou. (2022) Centrosome Defects in Hematological Malignancies: Molecular Mechanisms and Therapeutic Insights. Blood Science 4:3, pages 143-151.
Crossref
Crossref
Zhengang Duan, Lei Cai, Jin Cao & Wei Wu. (2022) Polo‑like kinase 4 is associated with advanced TNM stages and reduced survival and its inhibition improves chemosensitivity in colorectal cancer. Oncology Letters 24:2.
Crossref
Crossref
Kainat Zahra, Maria Shabbir, Yasmin Badshah, Janeen H. Trembley, Zunaira Badar, Khushbukhat Khan, Tayyaba Afsar, Ali Almajwal, Nawaf W. Alruwaili & Suhail Razak. (2022) Determining KLF14 tertiary structure and diagnostic significance in brain cancer progression. Scientific Reports 12:1.
Crossref
Crossref
Karuna Mittal, Jaspreet Kaur, Shaligram Sharma, Nivya Sharma, Guanhao Wei, Ishita Choudhary, Precious Imhansi-Jacob, Nagini Maganti, Shrikant Pawar, Padmashree Rida, Michael S. Toss, Mohammed Aleskandarany, Emiel A. Janssen, Håvard Søiland, Meenakshi. V. Gupta, Michelle D. Reid, Emad A. Rakha & Ritu Aneja. (2022) Hypoxia Drives Centrosome Amplification in Cancer Cells via HIF1α-dependent Induction of Polo-Like Kinase 4. Molecular Cancer Research 20:4, pages 596-606.
Crossref
Crossref
Aileen Roth, Adrian Gihring, Joachim Bischof, Leiling Pan, Franz Oswald & Uwe Knippschild. (2022) CK1 Is a Druggable Regulator of Microtubule Dynamics and Microtubule-Associated Processes. Cancers 14:5, pages 1345.
Crossref
Crossref
Yingchu Gu, Runze Zhang, Bin Jiang, Xin Xu, Jun Jie Guan, Xing Jie Jiang, Yuan Zhou, You Lang Zhou & Xiangdong Chen. (2021) Repair of Spinal Cord Injury by Inhibition of PLK4 Expression Through Local Delivery of siRNA-Loaded Nanoparticles. Journal of Molecular Neuroscience 72:3, pages 544-554.
Crossref
Crossref
Meysam Moghbeli. (2021) Molecular interactions of miR-338 during tumor progression and metastasis. Cellular & Molecular Biology Letters 26:1.
Crossref
Crossref
Yi Luan, Mingli Li, Yi Zhao, Qianqian Li, Jia Wen, Siqi Gao & Yang Yang. (2021) Centrosomal-associated Proteins: Potential therapeutic targets for solid tumors?. Biomedicine & Pharmacotherapy 144, pages 112292.
Crossref
Crossref
Ursula Blyth, Laurentiu Craciunas, Gavin Hudson & Meenakshi Choudhary. (2021) Maternal germline factors associated with aneuploid pregnancy loss: a systematic review. Human Reproduction Update 27:5, pages 866-884.
Crossref
Crossref
Monika Kressin, Daniela Fietz, Sven Becker & Klaus Strebhardt. (2021) Modelling the Functions of Polo-Like Kinases in Mice and Their Applications as Cancer Targets with a Special Focus on Ovarian Cancer. Cells 10:5, pages 1176.
Crossref
Crossref
Debra R. Garvey, Gagan Chhabra, Mary A. Ndiaye & Nihal Ahmad. (2021) Role of Polo-Like Kinase 4 (PLK4) in Epithelial Cancers and Recent Progress in its Small Molecule Targeting for Cancer Management. Molecular Cancer Therapeutics 20:4, pages 632-640.
Crossref
Crossref
Prajwal Dhokne, Akash P. Sakla & Nagula Shankaraiah. (2021) Structural insights of oxindole based kinase inhibitors as anticancer agents: Recent advances. European Journal of Medicinal Chemistry 216, pages 113334.
Crossref
Crossref
Christopher Jeyaseelan S., Milton Franklin Benial A. & Kaviyarasu K.. (2020)
Vibrational, spectroscopic, chemical reactivity, molecular docking and in vitro anticancer activity studies against
A549
lung cancer cell lines of
5‐Bromo
‐indole‐3‐carboxaldehyde
. Journal of Molecular Recognition 34:3.
Crossref
Crossref
Zhaoying Xu, Yongfa Sun, Danfeng Wang, Huifang Sun & Xiaojun Liu. (2020) SNHG16 promotes tumorigenesis and cisplatin resistance by regulating miR-338-3p/PLK4 pathway in neuroblastoma cells. Cancer Cell International 20:1.
Crossref
Crossref
Peisheng Jia, Erhu Wei, Huiqiong Liu, Tingting Wu & Huaili Wang. (2020)
Silencing of
long non‐coding RNA
DLX6‐AS1
weakens neuroblastoma progression by the
miR
‐513c‐5p/
PLK4
axis
. IUBMB Life 72:12, pages 2627-2636.
Crossref
Crossref
Joseph Y. Ong, Michelle C. Bradley & Jorge Z. Torres. (2020) Phospho‐regulation of mitotic spindle assembly. Cytoskeleton 77:12, pages 558-578.
Crossref
Crossref
Sophie L. Kerschner-Morales, Marie Kühne, Sabine Becker, James F. Beck & Jürgen Sonnemann. (2020) Anticancer effects of the PLK4 inhibitors CFI-400945 and centrinone in Ewing’s sarcoma cells. Journal of Cancer Research and Clinical Oncology 146:11, pages 2871-2883.
Crossref
Crossref
Qing Li, LingBing Meng & DePing Liu. (2020) Screening and Identification of Therapeutic Targets for Pulmonary Arterial Hypertension Through Microarray Technology. Frontiers in Genetics 11.
Crossref
Crossref
Oksana Goroshchuk, Linda Vidarsdottir, Ann-Charlotte Björklund, Alexander S. Hamil, Iryna Kolosenko, Steven F. Dowdy & Caroline Palm-Apergi. (2020) Targeting Plk1 with siRNNs in primary cells from pediatric B-cell acute lymphoblastic leukemia patients. Scientific Reports 10:1.
Crossref
Crossref
Xiao‐Dong Yang, Wenguo Li, Shuangyan Zhang, Dandan Wu, Xiaoli Jiang, Rong Tan, Xiaoyin Niu, Qijun Wang, Xuefeng Wu, Zhiduo Liu, Lin‐Feng Chen, Jun Qin & Bing Su. (2019)
PLK
4 deubiquitination by Spata2‐CYLD suppresses NEK7‐mediated NLRP3 inflammasome activation at the centrosome
. The EMBO Journal 39:2.
Crossref
Crossref
Ting Cao, Shijie Yi, Xuefeng Yang & Qing Wu. (2020) Clinical Significance of Polo-Like Kinase 4 as a Marker for Advanced Tumor Stage and Dismal Prognosis in Patients With Surgical Gastric Cancer. Technology in Cancer Research & Treatment 19, pages 153303382093553.
Crossref
Crossref
Yi Zhao & Xin Wang. (2019) PLK4: a promising target for cancer therapy. Journal of Cancer Research and Clinical Oncology 145:10, pages 2413-2422.
Crossref
Crossref
Stefani Stoll, Shanna Bitencourt, Stefan Laufer & Márcia Inês Goettert. (2019) Myricetin inhibits panel of kinases implicated in tumorigenesis. Basic & Clinical Pharmacology & Toxicology 125:1, pages 3-7.
Crossref
Crossref
Gianmarco Pallavicini, Gaia E. Berto & Ferdinando Di Cunto. (2019) Precision Revisited: Targeting Microcephaly Kinases in Brain Tumors. International Journal of Molecular Sciences 20:9, pages 2098.
Crossref
Crossref
Oksana Goroshchuk, Iryna Kolosenko, Linda Vidarsdottir, Alireza Azimi & Caroline Palm-Apergi. (2018) Polo-like kinases and acute leukemia. Oncogene 38:1, pages 1-16.
Crossref
Crossref