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Expert Opinion on Therapeutic Targets Volume 25, 2021 - Issue 1
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Review

Emerging therapeutic targets for cardiac arrhythmias: role of STAT3 in regulating cardiac fibroblast function

Nehal J. Patela The Frick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA;b Department of Biomedical Engineering, College of Engineering, the Ohio State University, Columbus, OH, USAView further author information
,
Drew M. Nassala The Frick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA;b Department of Biomedical Engineering, College of Engineering, the Ohio State University, Columbus, OH, USAView further author information
,
Daniel Gratza The Frick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA;b Department of Biomedical Engineering, College of Engineering, the Ohio State University, Columbus, OH, USAView further author information
&
Thomas J. Hunda The Frick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA;b Department of Biomedical Engineering, College of Engineering, the Ohio State University, Columbus, OH, USA;c Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USACorrespondence[email protected]
View further author information
Pages 63-73 | Received 08 Sep 2020, Accepted 05 Nov 2020, Published online: 23 Nov 2020

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Alexander J. Winkle, Drew M. Nassal, Rebecca Shaheen, Evelyn Thomas, Shivangi Mohta, Daniel Gratz, Seth H. Weinberg & Thomas J. Hund. (2022) Emerging therapeutic targets for cardiac hypertrophy. Expert Opinion on Therapeutic Targets 26:1, pages 29-40.
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Articles from other publishers (6)

Guang-Feng Zuo, Li-Guo Wang, Lu Huang, Yi-Fei Ren, Zhen Ge, Zuo-Ying Hu, Jun-Jie Zhang & Shao-Liang Chen. (2023) TAX1BP1 downregulation by STAT3 in cardiac fibroblasts contributes to diabetes-induced heart failure with preserved ejection fraction. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, pages 166979.
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Jingjing Zhang, Ji Cao, Jianan Qian, Xiaosong Gu, Wei Zhang & Xiangfan Chen. (2023) Regulatory mechanism of CaMKII δ mediated by RIPK3 on myocardial fibrosis and reversal effects of RIPK3 inhibitor GSK'872. Biomedicine & Pharmacotherapy 166, pages 115380.
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Xiaojuan Yu, Wen Peng, Yaoxing Wang, Wenjun Xu, Wentong Chen, Lei Huang, Hu Xu, Xinyu He, Sheng Wang, Qianqian Sun, Wenjie Lu & Youzhi Xu. (2023) Palmitic Acid Inhibits the Growth and Metastasis of Gastric Cancer by Blocking the STAT3 Signaling Pathway. Cancers 15:2, pages 388.
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Zirui Qiu, Yawen Zhao, Tian Tao, Wenying Guo, Ruonan Liu, Jingmin Huang & Geyang Xu. (2022) Activation of PPARα Ameliorates Cardiac Fibrosis in Dsg2-Deficient Arrhythmogenic Cardiomyopathy. Cells 11:20, pages 3184.
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Dijana Stojanovic, Valentina Mitic, Miodrag Stojanovic, Jelena Milenkovic, Aleksandra Ignjatovic & Maja Milojkovic. (2022) The Scientific Rationale for the Introduction of Renalase in the Concept of Cardiac Fibrosis. Frontiers in Cardiovascular Medicine 9.
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Drew M. Nassal, Nehal J. Patel, Sathya D. Unudurthi, Rebecca Shaheen, Jane Yu, Peter J. Mohler & Thomas J. Hund. (2021) Ca2+/calmodulin kinase II–dependent regulation of βIV-spectrin modulates cardiac fibroblast gene expression, proliferation, and contractility. Journal of Biological Chemistry 297:1, pages 100893.
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