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Expert Opinion on Therapeutic Targets Volume 26, 2022 - Issue 3
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Review

Omentin-1: a newly discovered warrior against metabolic related diseases

Aizhen Zhaoa Department of Neurology, Xi’an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi’an No. 3 Hospital, the Affiliated Hospital of Northwest University. School of Life Sciences and Medicine, Northwest University, Xi’an, China;b Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. Faculty of Life Sciences, Northwest University, Xi’an, ChinaView further author information
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Haoxiang Xiaoa Department of Neurology, Xi’an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi’an No. 3 Hospital, the Affiliated Hospital of Northwest University. School of Life Sciences and Medicine, Northwest University, Xi’an, China;b Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. Faculty of Life Sciences, Northwest University, Xi’an, ChinaView further author information
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Yanli Zhua Department of Neurology, Xi’an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi’an No. 3 Hospital, the Affiliated Hospital of Northwest University. School of Life Sciences and Medicine, Northwest University, Xi’an, China;b Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. Faculty of Life Sciences, Northwest University, Xi’an, ChinaView further author information
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Shuai Liua Department of Neurology, Xi’an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi’an No. 3 Hospital, the Affiliated Hospital of Northwest University. School of Life Sciences and Medicine, Northwest University, Xi’an, China;b Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. Faculty of Life Sciences, Northwest University, Xi’an, ChinaView further author information
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Shaofei Zhanga Department of Neurology, Xi’an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi’an No. 3 Hospital, the Affiliated Hospital of Northwest University. School of Life Sciences and Medicine, Northwest University, Xi’an, China;b Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. Faculty of Life Sciences, Northwest University, Xi’an, ChinaView further author information
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Zhi Yanga Department of Neurology, Xi’an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi’an No. 3 Hospital, the Affiliated Hospital of Northwest University. School of Life Sciences and Medicine, Northwest University, Xi’an, China;b Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. Faculty of Life Sciences, Northwest University, Xi’an, ChinaView further author information
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Luyang Dua Department of Neurology, Xi’an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi’an No. 3 Hospital, the Affiliated Hospital of Northwest University. School of Life Sciences and Medicine, Northwest University, Xi’an, China;b Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. Faculty of Life Sciences, Northwest University, Xi’an, ChinaView further author information
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Xiyang Lia Department of Neurology, Xi’an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi’an No. 3 Hospital, the Affiliated Hospital of Northwest University. School of Life Sciences and Medicine, Northwest University, Xi’an, China;b Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. Faculty of Life Sciences, Northwest University, Xi’an, ChinaView further author information
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Xiaochen Niua Department of Neurology, Xi’an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi’an No. 3 Hospital, the Affiliated Hospital of Northwest University. School of Life Sciences and Medicine, Northwest University, Xi’an, China;b Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. Faculty of Life Sciences, Northwest University, Xi’an, ChinaView further author information
,
Changyu Wanga Department of Neurology, Xi’an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi’an No. 3 Hospital, the Affiliated Hospital of Northwest University. School of Life Sciences and Medicine, Northwest University, Xi’an, ChinaView further author information
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Yang Yanga Department of Neurology, Xi’an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi’an No. 3 Hospital, the Affiliated Hospital of Northwest University. School of Life Sciences and Medicine, Northwest University, Xi’an, China;b Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. Faculty of Life Sciences, Northwest University, Xi’an, ChinaCorrespondence[email protected]
View further author information
&
Ye Tiana Department of Neurology, Xi’an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi’an No. 3 Hospital, the Affiliated Hospital of Northwest University. School of Life Sciences and Medicine, Northwest University, Xi’an, China;b Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. Faculty of Life Sciences, Northwest University, Xi’an, ChinaCorrespondence[email protected]
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Pages 275-289 | Received 21 Dec 2021, Accepted 31 Jan 2022, Published online: 10 Feb 2022

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Chunmeng Yao, Juanjuan Ou, Liping Zhou & Junlan Liu. (2023) Correlation of serum omentin-1 level with clinical features and major adverse cardiac and cerebral events in patients undergoing continuous ambulatory peritoneal dialysis. Scandinavian Journal of Clinical and Laboratory Investigation 83:2, pages 119-124.
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Xiaoshi Sun, Tianlian Li, Yumeng Tian, Shuying Ren, Ling Li & Ping Li. (2022) Omentin as an Independent Predictor of Metabolic Syndrome and Obesity Among Adolescents in Northeast China. Diabetes, Metabolic Syndrome and Obesity 15, pages 3913-3922.
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Articles from other publishers (11)

Amer Ahmed, Aasia Bibi, Massimo Valoti & Fabio Fusi. (2023) Perivascular Adipose Tissue and Vascular Smooth Muscle Tone: Friends or Foes?. Cells 12:8, pages 1196.
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Qin Zhang, Shuaihang Chen, Yani Ke, Qicong Li, Chenglu Shen, Yuting Ruan, Kaihan Wu, Jie Hu & Shan Liu. (2023) Association of circulating omentin level and metabolic-associated fatty liver disease: a systematic review and meta-analysis. Frontiers in Endocrinology 14.
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Ningning She, Na Liu, Xiaoyong Ren & Haiqin Liu. (2023) Association between omentin and obstructive sleep apnea: A meta‐analysis. The Clinical Respiratory Journal 17:3, pages 139-147.
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Fnu Deepika, Siresha Bathina & Reina Armamento-Villareal. (2023) Novel Adipokines and Their Role in Bone Metabolism: A Narrative Review. Biomedicines 11:2, pages 644.
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Clemens An, Ilissa Pipia, Ana-Sofia Ruiz, Ivonne Argüelles, Martino An, Saima Wase & Guang Peng. (2023) The molecular link between obesity and genomic instability in cancer development. Cancer Letters 555, pages 216035.
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Marcelina Sperling, Teresa Grzelak, Marta Pelczyńska, Paweł Bogdański, Dorota Formanowicz & Krystyna Czyżewska. (2023) Association of Serum Omentin-1 Concentration with the Content of Adipose Tissue and Glucose Tolerance in Subjects with Central Obesity. Biomedicines 11:2, pages 331.
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Susanne Schüler-Toprak, Olaf Ortmann, Christa Buechler & Oliver Treeck. (2022) The Complex Roles of Adipokines in Polycystic Ovary Syndrome and Endometriosis. Biomedicines 10:10, pages 2503.
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Jingui Hu, Tao Liu, Fei Fu, Zekun Cui, Qiong Lai, Yuanyuan Zhang, Boyang Yu, Fuming Liu, Junping Kou & Fang Li. (2022) Omentin1 ameliorates myocardial ischemia-induced heart failure via SIRT3/FOXO3a-dependent mitochondrial dynamical homeostasis and mitophagy. Journal of Translational Medicine 20:1.
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Davide Bolignano, Marta Greco, Valentina Arcidiacono, Pierangela Presta, Alfredo Caglioti, Michele Andreucci, Francesco Dragone, Daniela Patrizia Foti & Giuseppe Coppolino. (2022) Circulating Omentin-1, Sustained Inflammation and Hyperphosphatemia at the Interface of Subclinical Atherosclerosis in Chronic Kidney Disease Patients on Chronic Renal Replacement Therapy. Medicina 58:7, pages 890.
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Hongnian Wu, Dan Huang, Hong Zhou, Xueqin Sima, Zhe Wu, Yanling Sun, Long Wang, Ying Ruan, Qian Wu, Feng Wu, Tonghui She, Ying Chu, Qizhi Huang, Zhifeng Ning & Hao Zhang. (2022) Metformin: A promising drug for human cancers (Review). Oncology Letters 24:1.
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Esra Sinem Kemer Doğan & Nizami Duran. (2022) Is periodontal inflamed surface area associated with serum and salivary levels of IL-1β, visfatin, and omentin-1 in overweight/obese patients?. Clinical Oral Investigations 26:8, pages 5351-5358.
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