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Expert Review of Anticancer Therapy Volume 17, 2017 - Issue 12
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Review

New targets and therapies for gastrointestinal stromal tumors

Agnieszka WozniakLaboratory of Experimental Oncology, Department of Oncology, KU Leuven, Leuven, BelgiumCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-9726-144XView further author information
ORCID Icon,
Yemarshet K. GebreyohannesLaboratory of Experimental Oncology, Department of Oncology, KU Leuven, Leuven, BelgiumView further author information
,
Maria Debiec-RychterDepartment of Human Genetics, KU Leuven, Leuven, BelgiumView further author information
&
Patrick SchöffskiLaboratory of Experimental Oncology, Department of Oncology, KU Leuven, Leuven, Belgium;Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, Leuven, BelgiumView further author information
Pages 1117-1129 | Received 20 Sep 2017, Accepted 31 Oct 2017, Published online: 20 Nov 2017

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Mahmoud Mohammadi & Hans Gelderblom. (2021) Systemic therapy of advanced/metastatic gastrointestinal stromal tumors: an update on progress beyond imatinib, sunitinib, and regorafenib. Expert Opinion on Investigational Drugs 30:2, pages 143-152.
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Christopher P Wilding, Mark L Elms, Ian Judson, Aik-Choon Tan, Robin L Jones & Paul H Huang. (2019) The landscape of tyrosine kinase inhibitors in sarcomas: looking beyond pazopanib. Expert Review of Anticancer Therapy 19:11, pages 971-991.
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Articles from other publishers (14)

Heidi Maria Namløs, Ksenia Khelik, Sigve Nakken, Daniel Vodák, Eivind Hovig, Ola Myklebost, Kjetil Boye & Leonardo A. Meza‐Zepeda. (2023) Chromosomal instability and a deregulated cell cycle are intrinsic features of high‐risk gastrointestinal stromal tumours with a metastatic potential. Molecular Oncology 17:11, pages 2432-2450.
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Xiangchen Hu, Peng Su, Bo Liu, Jingwei Guo, Zitong Wang, Cai He, Zhe Wang & Youwei Kou. (2023) Characterization of a Human Gastrointestinal Stromal Tumor Cell Line Established by SV40LT-Mediated Immortalization. International Journal of Molecular Sciences 24:17, pages 13640.
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Xiangchen Hu, Zhe Wang, Peng Su, Qiqi Zhang & Youwei Kou. (2022) Advances in the research of the mechanism of secondary resistance to imatinib in gastrointestinal stromal tumors. Frontiers in Oncology 12.
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Xiaobin Cheng, Jinhai Wang, Sen Lu, Weina Fan & Weilin Wang. (2021) Aurora kinase A (AURKA) promotes the progression and imatinib resistance of advanced gastrointestinal stromal tumors. Cancer Cell International 21:1.
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Christos Vallilas, Panagiotis Sarantis, Anastasios Kyriazoglou, Evangelos Koustas, Stamatios Theocharis, Athanasios G. Papavassiliou & Michalis V. Karamouzis. (2021) Gastrointestinal Stromal Tumors (GISTs): Novel Therapeutic Strategies with Immunotherapy and Small Molecules. International Journal of Molecular Sciences 22:2, pages 493.
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Robert RoskoskiJr.Jr.. (2020) The role of small molecule Flt3 receptor protein-tyrosine kinase inhibitors in the treatment of Flt3-positive acute myelogenous leukemias. Pharmacological Research 155, pages 104725.
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Hans Gelderblom, Robin L. Jones, Suzanne George, Claudia Valverde Morales, Charlotte Benson, Jean-Yves Blay, Daniel J. Renouf, Toshihiko Doi, Axel Le Cesne, Michael Leahy, Sabine Hertle, Paola Aimone, Ulrike Brandt & Patrick Schӧffski. (2020) Imatinib in combination with phosphoinositol kinase inhibitor buparlisib in patients with gastrointestinal stromal tumour who failed prior therapy with imatinib and sunitinib: a Phase 1b, multicentre study. British Journal of Cancer 122:8, pages 1158-1165.
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Weizhen Liu, Xiangyu Zeng, Yuping Yin, Chengguo Li, Wenchang Yang, Wenze Wan, Liang Shi, Guobin Wang, Kaixiong Tao & Peng Zhang. (2019) Targeting the WEE1 kinase strengthens the antitumor activity of imatinib via promoting KIT autophagic degradation in gastrointestinal stromal tumors. Gastric Cancer 23:1, pages 39-51.
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Jae-Joon Kim, Min-Hee Ryu, Changhoon Yoo, Mo Youl Beck, Jung Eun Ma & Yoon-Koo Kang. (2019) Phase II Trial of Continuous Regorafenib Dosing in Patients with Gastrointestinal Stromal Tumors After Failure of Imatinib and Sunitinib. The Oncologist 24:11, pages e1212-e1218.
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K. I. Anoshkin, K. O. Karandasheva, K. M. Goryacheva, Y. V. Shpot, A. Z. Vinarov, D. V. Zaletaev, A. S. Tanas & V. V. Strelnikov. (2019) Germline and Somatic Mutations of Genes Involved in Tumor Formation in Sporadic Renal Angiomyolipoma. Russian Journal of Genetics 55:9, pages 1113-1118.
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Hariti Saluja, Christos S. Karapetis, Susanne K. Pedersen, Graeme P. Young & Erin L. Symonds. (2018) The Use of Circulating Tumor DNA for Prognosis of Gastrointestinal Cancers. Frontiers in Oncology 8.
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Robert RoskoskiJr.Jr.. (2018) The role of small molecule Kit protein-tyrosine kinase inhibitors in the treatment of neoplastic disorders. Pharmacological Research 133, pages 35-52.
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Robert RoskoskiJr.Jr.. (2018) The role of small molecule platelet-derived growth factor receptor (PDGFR) inhibitors in the treatment of neoplastic disorders. Pharmacological Research 129, pages 65-83.
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Ulrich Ronellenfitsch & Peter Hohenberger. (2018) Surgery for Gastrointestinal Stromal Tumors: State of the Art of Laparoscopic Resection and Surgery for M1 Tumors. Visceral Medicine 34:5, pages 367-374.
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