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Expert Opinion on Drug Safety Volume 16, 2017 - Issue 9
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Review

An update on anesthetics and impact on the brain

Vincenzo FodaleDepartment of Human Pathology of Adult and Evolutive Age, Section of Anesthesiology, University of Messina, Messina, ItalyCorrespondence[email protected]
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,
Vincenzo F. TripodiDepartment of Cardiac Surgery, Unit of Cardioanesthesia, Metropolitan Hospital “Bianchi Melacrino Morelli”, Reggio Calabria, ItalyView further author information
,
Olivia PennaDepartment of Human Pathology of Adult and Evolutive Age, Section of Anesthesiology, University of Messina, Messina, ItalyView further author information
,
Fausto FamàDepartment of Human Pathology of Adult and Evolutive Age, Section of Anesthesiology, University of Messina, Messina, ItalyView further author information
,
Francesco SquadritoDepartment of Clinical and Experimental Medicine, University of Messina, Messina, ItalyView further author information
,
Epifanio MondelloDepartment of Human Pathology of Adult and Evolutive Age, Section of Anesthesiology, University of Messina, Messina, ItalyView further author information
&
Antonio DavidDepartment of Human Pathology of Adult and Evolutive Age, Section of Anesthesiology, University of Messina, Messina, ItalyView further author information
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Pages 997-1008 | Received 03 Apr 2017, Accepted 03 Jul 2017, Published online: 18 Jul 2017

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Hongxia Li, Meiqing Du, Weimin Xu & Zengfu Wang. (2021) MiR-191 downregulation protects against isoflurane-induced neurotoxicity through targeting BDNF. Toxicology Mechanisms and Methods 31:5, pages 367-373.
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Articles from other publishers (22)

Samaneh Nakhaee & Omid Mehrpour. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 463 472 .
Oxana Semyachkina-Glushkovskaya, Konstantin Sergeev, Nadezhda Semenova, Andrey Slepnev, Anatoly Karavaev, Alexey Hramkov, Mikhail Prokhorov, Ekaterina Borovkova, Inna Blokhina, Ivan Fedosov, Alexander Shirokov, Alexander Dubrovsky, Andrey Terskov, Maria Manzhaeva, Valeria Krupnova, Alexander Dmitrenko, Daria Zlatogorskaya, Viktoria Adushkina, Arina Evsukova, Matvey Tuzhilkin, Inna Elizarova, Egor Ilyukov, Dmitry Myagkov, Dmitry Tuktarov & Jürgen Kurths. (2023) Machine Learning Technology for EEG-Forecast of the Blood–Brain Barrier Leakage and the Activation of the Brain’s Drainage System during Isoflurane Anesthesia. Biomolecules 13:11, pages 1605.
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Xinxin Yang & Xiangdong Chen. (2022) The Crosstalk between the Blood–Brain Barrier Dysfunction and Neuroinflammation after General Anaesthesia. Current Issues in Molecular Biology 44:11, pages 5700-5717.
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J. KNOR, V. PACOVSKÝ, V. NEDVĚD, K. KEHÁROVÁ, A. KURZOVÁ & J. MÁLEK. (2022) Fascia iliaca Block with General Anaesthesia vs. Subarachnoid Morphine Block in Total Hip Arthroplasty. Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 89:5, pages 339-343.
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Nazan DEĞİRMENCİ. (2022) Perioperative anxiety in patients undergoing septorhinoplastySeptorinoplasti hastalarında perioperatif anksiyete. Anadolu Kliniği Tıp Bilimleri Dergisi 27:3, pages 281-286.
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Michael S. Avidan, Elizabeth L. Whitlock & George A. Mashour. (2022) General Anesthesia and Postoperative Neurocognitive Outcomes. JAMA 327:1, pages 36.
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Y Yin, H Li, J Wang, Y Kong, J Chang & G Chu. (2022) Implication of microglia in ketamine-induced long-term cognitive impairment in murine pups. Human & Experimental Toxicology 41, pages 096032712211287.
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Yang Shen, Xianchen Li & Junyan Yao. (2022) Develop a Clinical Prediction Model for Postoperative Cognitive Dysfunction after Major Noncardiac Surgery in Elderly Patients: A Protocol for a Prospective Observational Study. Gerontology 68:5, pages 538-545.
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James P. RathmellMichael S. Avidan. (2021) Patient-Centered Outcomes after General and Spinal Anesthesia. New England Journal of Medicine 385:22, pages 2088-2089.
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Qiaoling Wu, You Shang, Tu Shen, Feifei Liu & Wei Zhang. (2021) Biochanin A protects SH-SY5Y cells against isoflurane-induced neurotoxicity by suppressing oxidative stress and apoptosis. NeuroToxicology 86, pages 10-18.
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Tarun Pant, Johanna K. DiStefano, Sara Logan & Zeljko J. Bosnjak. (2020) Emerging Role of Long Noncoding RNAs in Perioperative Neurocognitive Disorders and Anesthetic-Induced Developmental Neurotoxicity. Anesthesia & Analgesia 132:6, pages 1614-1625.
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Fan Yang, Hai Zhao, Kaiyuan Zhang, Xiuying Wu & Hongtao Liu. (2020) Research progress and treatment strategies for anesthetic neurotoxicity. Brain Research Bulletin 164, pages 37-44.
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Xinchun Mei, Hai-Lin Zheng, Cheng Li, Xin Ma, Hui Zheng, Edward Marcantonio, Zhongcong Xie & Yuan Shen. (2020) The Effects of Propofol and Sevoflurane on Postoperative Delirium in Older Patients: A Randomized Clinical Trial Study. Journal of Alzheimer's Disease 76:4, pages 1627-1636.
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Nancy Pearl Solomon, Angela M. Dietsch & Katie Dietrich-Burns. (2020) Predictors of swallowing outcomes in patients with combat-injury related dysphagia. Journal of Trauma and Acute Care Surgery 89:2S, pages S192-S199.
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О.І. Koval. (2020) SUBSTANTIATION OF A SAFE PERIOD OF TIME FOR THE ORAL CAVITY SANITATION UNDER GENERAL ANESTHESIA IN CHILDREN AGED 12-18 YEARS. World of Medicine and Biology 16:73, pages 057.
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Jinlian Qi, Yingping Jia, Wenhua Wang, Haibing Lu, Yuan Wang & Zhengchen Li. (2018) The role of Bag2 in neurotoxicity induced by the anesthetic sevoflurane. Journal of Cellular Biochemistry 120:5, pages 7551-7559.
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Izabela Z. Schultz, Amir A. Sepehry & Sarah C. Greer. (2018) Anoxia-Hypoxia in Forensic Neuropsychological Assessment: Cognitive Impact of Pulmonary Injuries, Respiratory Distress, Cerebral Blood Hypoperfusion, and Major Surgeries. Psychological Injury and Law 11:2, pages 153-170.
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Ferenc Zsila. (2018) The Un(f)told Story of General Anesthesia. ChemBioChem 19:9, pages 895-901.
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Ziyi Wu, Xingyue Li, Yi Zhang, Dongyi Tong, Lili Wang & Ping Zhao. (2018) Effects of Sevoflurane Exposure During Mid-Pregnancy on Learning and Memory in Offspring Rats: Beneficial Effects of Maternal Exercise. Frontiers in Cellular Neuroscience 12.
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Jason Powell & Steven Powell. (2018) Obstructive Sleep Apnea in the Very Young. Current Otorhinolaryngology Reports 6:1, pages 48-55.
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Syed Z Imam, Zhen He, Elvis Cuevas, Hector Rosas-Hernandez, Susan M Lantz, Sumit Sarkar, James Raymick, Bonnie Robinson, Joseph P Hanig, David Herr, Denise MacMillan, Aaron Smith, Serguei Liachenko, Sherry Ferguson, James O’Callaghan, Diane Miller, Christopher Somps, Ingrid D Pardo, William Slikker Jr, Jennifer B Pierson, Ruth Roberts, Binsheng Gong, Weida Tong, Michael Aschner, Mary J Kallman, David Calligaro & Merle G Paule. (2017) Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity: A trimethyltin study. Experimental Biology and Medicine 243:3, pages 228-236.
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Marco Cascella & Sabrina Bimonte. (2017) The role of general anesthetics and the mechanisms of hippocampal and extra-hippocampal dysfunctions in the genesis of postoperative cognitive dysfunction. Neural Regeneration Research 12:11, pages 0.
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