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Expert Opinion on Drug Safety Volume 17, 2018 - Issue 5
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Original Research

Does high-dose benzodiazepine abuse really produce liver toxicity? Results from a series of 201 benzodiazepine monoabusers

Fabio LugoboniDepartment of Medicine, Verona University Hospital, Verona, ItalyORCID Iconhttp://orcid.org/0000-0002-1434-4432View further author information
ORCID Icon,
Antonio MirijelloDepartment of Medical Sciences, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, ItalyORCID Iconhttp://orcid.org/0000-0003-3932-3803View further author information
ORCID Icon,
Laura MorbioliDepartment of Medicine, Verona University Hospital, Verona, ItalyView further author information
,
Elena ArzentonDepartment of Medicine, Verona University Hospital, Verona, ItalyView further author information
,
Roberto LeoneDepartment of Medicine, Verona University Hospital, Verona, ItalyView further author information
,
Marco FacciniDepartment of Medicine, Verona University Hospital, Verona, ItalyView further author information
,
Rebecca CasariDepartment of Medicine, Verona University Hospital, Verona, ItalyView further author information
,
Salvatore De CosmoDepartment of Medical Sciences, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, ItalyORCID Iconhttp://orcid.org/0000-0001-8787-8286View further author information
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Antonio GasbarriniDepartment of Internal Medicine, Gastroenterology and Hepatology, Catholic University of Rome, Rome, ItalyORCID Iconhttp://orcid.org/0000-0002-6230-1779View further author information
ORCID Icon &
Giovanni AddoloratoDepartment of Internal Medicine, Gastroenterology and Hepatology, Catholic University of Rome, Rome, ItalyCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-1522-9946View further author information
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Pages 451-456 | Received 13 Dec 2017, Accepted 28 Feb 2018, Published online: 06 Apr 2018

Citations (7)

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Fabio Lugoboni, Antonio Mirijello, Laura Morbioli, Marco Faccini, Rebecca Casari, Salvatore De Cosmo, Antonio Gasbarrini & Giovanni Addolorato. (2019) Zolpidem high-dose abuse: what about the liver? Results from a series of 107 patients. Expert Opinion on Drug Safety 18:8, pages 753-758.
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Articles from other publishers (6)

Wenting Lin, Yingjun Qin & Yuan Ren. (2024) Flunitrazepam and its metabolites induced brain toxicity: Insights from molecular dynamics simulation and transcriptomic analysis. Journal of Hazardous Materials 465, pages 133113.
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Chiara Fogliano, Chiara Maria Motta, Hervé Acloque, Bice Avallone & Rosa Carotenuto. (2023) Water contamination by delorazepam induces epigenetic defects in the embryos of the clawed frog Xenopus laevis. Science of The Total Environment 896, pages 165300.
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Jean‐Marc Cloos, Christopher Y. S. Lim Cow & Valéry Bocquet. (2021) Benzodiazepine high‐doses: The need for an accurate definition. International Journal of Methods in Psychiatric Research 30:4.
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Anna Benini, Rossella Gottardo, Cristiano Chiamulera, Anna Bertoldi, Lorenzo Zamboni & Fabio Lugoboni. (2021) Continuous Infusion of Flumazenil in the Management of Benzodiazepines Detoxification. Frontiers in Psychiatry 12.
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Mark Real, Michele S. Barnhill, Cory Higley, Jessica Rosenberg & James H. Lewis. (2018) Drug-Induced Liver Injury: Highlights of the Recent Literature. Drug Safety 42:3, pages 365-387.
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. (2018) Benzodiazepines abuse. Reactions Weekly 1706:1, pages 82-82.
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