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Research Article

Inhibition of Butyrylcholinesterase by Phenothiazine Derivatives

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Pages 197-202 | Published online: 30 Sep 2008

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Emin Garibov, Parham Taslimi, Afsun Sujayev, Zeynebe Bingol, Songul Çetinkaya, İlhami Gulçin, Sukru Beydemir, Vagif Farzaliyev, Saleh H. Alwasel & Claudiu T. Supuran. (2016) Synthesis of 4,5-disubstituted-2-thioxo-1,2,3,4-tetrahydropyrimidines and investigation of their acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase I/II inhibitory and antioxidant activities. Journal of Enzyme Inhibition and Medicinal Chemistry 31:sup3, pages 1-9.
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Krzysztof Lodarski, Jakub Jończyk, Natalia Guzior, Marek Bajda, Joanna Gładysz, Joanna Walczyk, Małgorzata Jeleń, Beata Morak-Młodawska, Krystian Pluta & Barbara Malawska. (2015) Discovery of butyrylcholinesterase inhibitors among derivatives of azaphenothiazines. Journal of Enzyme Inhibition and Medicinal Chemistry 30:1, pages 98-106.
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Honghua Zhang, Yuying Wang, Yuqing Wang, Xuelin Li, Shuzhi Wang & Zhen Wang. (2022) Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease. European Journal of Medicinal Chemistry 240, pages 114606.
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Maria Podsiedlik, Magdalena Markowicz-Piasecka & Joanna Sikora. (2022) The Influence of Selected Antipsychotic Drugs on Biochemical Aspects of Alzheimer’s Disease. International Journal of Molecular Sciences 23:9, pages 4621.
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Yepeng Luan, Jinyi Liu, Jianjun Gao & Jinhua Wang. (2019) The Design and Synthesis of Novel Phenothiazine Derivatives as Potential Cytotoxic Agents. Letters in Drug Design & Discovery 17:1, pages 57-67.
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Manpreet Kaur, Y. Shyma Mary, C. Yohannan Panicker, Hema Tresa Varghese, H.S. Yathirajan, K. Byrappa & Christian Van Alsenoy. (2014) Vibrational spectroscopic (FT-IR, FT-Raman) and quantum chemical calculations of 1-(5,5-dioxido-10H-phenothiazin-10-yl)ethanone. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 120, pages 445-455.
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Sultan Darvesh, Ian R. Macdonald & Earl Martin. (2013) Selectivity of phenothiazine cholinesterase inhibitors for neurotransmitter systems. Bioorganic & Medicinal Chemistry Letters 23:13, pages 3822-3825.
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Roney Anderson Nascimento de Aquino, Luzia Valentina Modolo, Rosemeire Brondi Alves & Ângelo de Fátima. (2013) Synthesis, kinetic studies and molecular modeling of novel tacrine dimers as cholinesterase inhibitors. Organic & Biomolecular Chemistry 11:48, pages 8395.
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Daniela Karlsson, Adyary Fallarero, Gerda Brunhofer, Claudia Mayer, Ohm Prakash, C. Gopi Mohan, Pia Vuorela & Thomas Erker. (2012) The exploration of thienothiazines as selective butyrylcholinesterase inhibitors. European Journal of Pharmaceutical Sciences 47:1, pages 190-205.
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B. Tasso, M. Catto, O. Nicolotti, F. Novelli, M. Tonelli, I. Giangreco, L. Pisani, A. Sparatore, V. Boido, A. Carotti & F. Sparatore. (2011) Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer’s disease. European Journal of Medicinal Chemistry 46:6, pages 2170-2184.
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R. Minitha, Y. Sheena Mary, Hema Tresa Varghese, C. Yohannan Panicker, Reena Ravindran, K. Raju & V. Manikantan Nair. (2011) FT-IR, FT-Raman and computational study of 1H-2,2-dimethyl-3H-phenothiazin-4[10H]-one. Journal of Molecular Structure 985:2-3, pages 316-322.
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Murat Oz, Dietrich E. Lorke, Mohammed Hasan & George A. Petroianu. (2010) Cellular and molecular actions of Methylene Blue in the nervous system. Medicinal Research Reviews 31:1, pages 93-117.
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Sultan Darvesh, Ian R. Pottie, Katherine V. Darvesh, Robert S. McDonald, Ryan Walsh, Sarah Conrad, Andrea Penwell, Diane Mataija & Earl Martin. (2010) Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants. Bioorganic & Medicinal Chemistry 18:6, pages 2232-2244.
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Katherine V. Darvesh, Ian R. Pottie, Robert S. McDonald, Earl Martin & Sultan Darvesh. 2010. Quantum Biochemistry. Quantum Biochemistry 757 780 .
Murat Oz, Dietrich E. Lorke & George A. Petroianu. (2009) Methylene blue and Alzheimer's disease. Biochemical Pharmacology 78:8, pages 927-932.
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Yasemin Yücel Yücel, Özden Tacal & Inci Özer. (2008) Comparative effects of cationic triarylmethane, phenoxazine and phenothiazine dyes on horse serum butyrylcholinesterase. Archives of Biochemistry and Biophysics 478:2, pages 201-205.
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Sultan Darvesh, Katherine V. Darvesh, Robert S. McDonald, Diane Mataija, Ryan Walsh, Sam Mothana, Oksana Lockridge & Earl Martin. (2008) Carbamates with Differential Mechanism of Inhibition Toward Acetylcholinesterase and Butyrylcholinesterase. Journal of Medicinal Chemistry 51:14, pages 4200-4212.
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Sultan Darvesh, Robert S. McDonald, Katherine V. Darvesh, Diane Mataija, Sarah Conrad, Geraldine Gomez, Ryan Walsh & Earl Martin. (2007) Selective reversible inhibition of human butyrylcholinesterase by aryl amide derivatives of phenothiazine. Bioorganic & Medicinal Chemistry 15:19, pages 6367-6378.
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Lianfeng Zhang, William A. Anderson, Steven Sawell & Carol Moralejo. (2007) Mechanistic analysis on the influence of humidity on photocatalytic decomposition of gas-phase chlorobenzene. Chemosphere 68:3, pages 546-553.
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Sultan Darvesh, Robert S. McDonald, Andrea Penwell, Sarah Conrad, Katherine V. Darvesh, Diane Mataija, Geraldine Gomez, Angela Caines, Ryan Walsh & Earl Martin. (2005) Structure–activity relationships for inhibition of human cholinesterases by alkyl amide phenothiazine derivatives. Bioorganic & Medicinal Chemistry 13:1, pages 211-222.
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