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Research Article

The extract of leaves of Acer truncatum Bunge: A natural inhibitor of fatty acid synthase with antitumor activity

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Pages 589-596 | Received 22 Feb 2006, Accepted 03 Apr 2006, Published online: 04 Oct 2008

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Wen-Hua Zhao, Li-Fang Gao, Wen Gao, Yong-Sheng Yuan, Chun-Chun Gao, Li-Ge Cao, Zi-Zheng Hu, Jian-Qiang Guo & Ying-Xia Zhang. (2011) Weight-reducing effect of Acer truncatum Bunge may be related to the inhibition of fatty acid synthase. Natural Product Research 25:4, pages 422-431.
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Wen-Hua Zhao, ChunChun Gao, Ying-Xia Zhang & Wei-Xi Tian. (2007) Evaluation of the inhibitory activities of aceraceous plants on fatty acid synthase. Journal of Enzyme Inhibition and Medicinal Chemistry 22:4, pages 501-510.
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Articles from other publishers (20)

Jiongyan Liu, Saisai Liang, Kailong Qin, Bingzheng Jia, Zhouzheng Ren, Xiaojun Yang & Xin Yang. (2023) Acer truncatum leaves extract modulates gut microbiota, improves antioxidant capacity, and alleviates lipopolysaccharide-induced inflammation in broilers. Poultry Science 102:10, pages 102951.
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Minyan Song, Li Wang, Yuting Zhang, Qiguang Wang, Xiao Han, Qi Yang, Junhong Zhang & Zaikang Tong. (2023) Temporospatial pattern of flavonoid metabolites and potential regulatory pathway of PbMYB211-coordinated kaempferol-3-O-rhamnoside biosynthesis in Phoebe bournei. Plant Physiology and Biochemistry 202, pages 107913.
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Xianyang Chen, Wangting Song, Yige Song, Hongli Cao, Xiao Xu, Shujia Li, Yanmin Fu, Teng Xue, Chunguang Ding, Feng Lin, Yuan Shi & Jiujun Li. (2023) Lipidomics reveal the cognitive improvement effects of Acer truncatum Bunge seed oil on hypoxic–ischemic encephalopathy rats . Food & Function 14:14, pages 6610-6623.
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Qiuyue Ma, Yuxiao Wang, Shushun Li, Jing Wen, Lu Zhu, Kunyuan Yan, Yiming Du, Shuxian Li, Liping Yan, Zhijun Xie, Yunzhou Lyu, Fei Shen & Qianzhong Li. (2023) Ribosome footprint profiling enables elucidating the systemic regulation of fatty acid accumulation in Acer truncatum. BMC Biology 21:1.
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Wangting Song, Ke Zhang, Teng Xue, Jiarui Han, Fangda Peng, Chunguang Ding, Feng Lin, Jiujun Li, Fat Tin Agassi Sze, Jianwen Gan & Xianyang Chen. (2022) Cognitive improvement effect of nervonic acid and essential fatty acids on rats ingesting Acer truncatum Bunge seed oil revealed by lipidomics approach . Food & Function 13:5, pages 2475-2490.
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Yan Liang, Fan Kong, Xiaofeng Ma & Qingyan Shu. (2022) Inhibitory Effect of Acer truncatum Bunge Seed Coat Extract on Fatty Acid Synthase, Differentiation and Lipid Accumulation in 3T3-L1 Adipocytes. Molecules 27:4, pages 1324.
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Qian Qiao, Fenfen Si, Chong Wu, Jiangyong Wang, Anning Zhang, Jihan Tao, Lin Zhang, Yan Liu & Zhen Feng. (2022) Transcriptome sequencing and flavonoid metabolism analysis in the leaves of three different cultivars of Acer truncatum. Plant Physiology and Biochemistry 171, pages 1-13.
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Yanxiao Fan, Fengke Lin, Ruifei Zhang, Miaomiao Wang, Ronghui Gu & Chunlin Long. (2022) Acer truncatum Bunge: A comprehensive review on ethnobotany, phytochemistry and pharmacology. Journal of Ethnopharmacology 282, pages 114572.
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Dong-Ju Chen, Xue-Gang Luo, Li-Hua Yan, Chuan-Ling Si, Nan Wang, Hong-Peng He & Tong-Cun Zhang. (2021) Transcriptome analysis of unsaturated fatty acids biosynthesis shows essential genes in sprouting of Acer truncatum Bunge seeds. Food Bioscience 41, pages 100739.
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Qiuyue Ma, Shushun Li, Jing Wen, Lu Zhu, Kunyuan Yan, Qianzhong Li, Shuxian Li & Bin Zhang. (2021) Transcriptome Analysis of Acer truncatum Seeds Reveals Candidate Genes Related to Oil Biosynthesis and Fatty Acid Metabolism. Journal of the American Society for Horticultural Science 146:2, pages 99-108.
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Wenmeng He, Minxia Yin, Ruijin Yang & Wei Zhao. (2020) Optimization of adlay (Coix lacryma-jobi) bran oil extraction: Variability in fatty acids profile and fatty acid synthase inhibitory activities. Biocatalysis and Agricultural Biotechnology 28, pages 101740.
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Rong-hui Gu, Taylan Morcol, Bo Liu, Min-jie Shi, Edward J. Kennelly & Chun-lin Long. (2019) GC–MS, UPLC-QTOF-MS, and bioactivity characterization of Acer truncatum seeds. Industrial Crops and Products 138, pages 111480.
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Ronghui Gu, Levi Rybalov, Adam Negrin, Taylan Morcol, Weiwen Long, Amanda K. Myers, Giorgis Isaac, Jimmy Yuk, Edward J. Kennelly & Chunlin Long. (2019) Metabolic Profiling of Different Parts of Acer truncatum from the Mongolian Plateau Using UPLC-QTOF-MS with Comparative Bioactivity Assays . Journal of Agricultural and Food Chemistry 67:5, pages 1585-1597.
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Lingguang Yang, Peipei Yin, Chi-Tang Ho, Miao Yu, Liwei Sun & Yujun Liu. (2018) Effects of thermal treatments on 10 major phenolics and their antioxidant contributions in Acer truncatum leaves and flowers . Royal Society Open Science 5:6, pages 180364.
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Lingguang Yang, Peipei Yin, Ke Li, Hang Fan, Qiang Xue, Xiang Li, Liwei Sun & Yujun Liu. (2018) Seasonal dynamics of constitutive levels of phenolic components lead to alterations of antioxidant capacities in Acer truncatum leaves. Arabian Journal of Chemistry 11:1, pages 14-25.
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Dong-Ju Chen, Li-Hua Yan, Qian Li, Cai-jiao Zhang, Chuan-Ling Si, Zhong-Yuan Li, Ya-Jian Song, Hao Zhou, Tong-Cun Zhang & Xue-Gang Luo. (2017) Bioconversion of conjugated linoleic acid by Lactobacillus plantarum CGMCC8198 supplemented with Acer truncatum bunge seeds oil. Food Science and Biotechnology 26:6, pages 1595-1611.
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Lingguang Yang, Peipei Yin, Hang Fan, Qiang Xue, Ke Li, Xiang Li, Liwei Sun & Yujun Liu. (2017) Response Surface Methodology Optimization of Ultrasonic-Assisted Extraction of Acer Truncatum Leaves for Maximal Phenolic Yield and Antioxidant Activity. Molecules 22:2, pages 232.
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Wenhua Zhao, Yuji Wang, Weijia Hao, Ming Zhao & Shiqi Peng. (2014) In vitro inhibition of fatty acid synthase by 1,2,3,4,6-penta-O-galloyl-β-d-glucose plays a vital role in anti-tumour activity. Biochemical and Biophysical Research Communications 445:2, pages 346-351.
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Wen-Hua Zhao, Chun-Yang Zhao, Li-Fang Gao, Fei-Fei Feng, Wen Gao, Zhen-Liang Chen, Feng Zhang, Li-Ge Cao, Xiao-Yu Bi, Yue Chen, Qi-Yao Zhu & Ying-Xia Zhang. (2008) The novel inhibitory effect of Pangdahai on fatty acid synthase. IUBMB Life 60:3, pages 185-194.
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Wen-Hua Zhao, Chun-Chun Gao, Xiao-Feng Ma, Xiao-Yu Bai & Ying-Xia Zhang. (2007) The isolation of 1,2,3,4,6-penta-O-galloyl-beta-d-glucose from Acer truncatum Bunge by high-speed counter-current chromatography. Journal of Chromatography B 850:1-2, pages 523-527.
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