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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 37, 2022 - Issue 1
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Research Papers

Anti-cancer and immunomodulatory evaluation of new nicotinamide derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: in vitro and in silico studies

Reda G. Yousefa Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, EgyptView further author information
,
Alaa Elwana Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, EgyptView further author information
,
Ibraheem M. M. Gobaarab Zoology Department, Faculty of Science (Boys), Al-Azhar University, Cairo, EgyptView further author information
,
Ahmed B. M. Mehanyb Zoology Department, Faculty of Science (Boys), Al-Azhar University, Cairo, EgyptView further author information
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Wagdy M. Eldehnac Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, EgyptView further author information
,
Souad A. El-Metwallyd Department of Basic Science, Higher Technological institute, 10th of Ramadan City, EgyptView further author information
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Bshra A. Alsfouke Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi ArabiaView further author information
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Eslam B. Elkaeedf Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi ArabiaView further author information
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Ahmed M. Metwalyg Pharmacognosy and Medicinal Plants Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt;h Biopharmaceutical Products Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria, EgyptCorrespondence[email protected]
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&
Ibrahim H. Eissaa Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, EgyptCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-6955-2263View further author information
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Pages 2206-2222 | Received 23 May 2022, Accepted 02 Aug 2022, Published online: 18 Aug 2022

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Mohammed A. Dahab, Hazem A. Mahdy, Hazem Elkady, Mohammed S. Taghour, Alaa Elwan, Mohamed A. Elkady, Elsayed G. E. Elsakka, Eslam B. Elkaeed, Aisha A. Alsfouk, Ibrahim M. Ibrahim, Ahmed M. Metwaly & Ibrahim H. Eissa. (2023) Semi-synthesized anticancer theobromine derivatives targeting VEGFR-2: in silico and in vitro evaluations. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-20.
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Articles from other publishers (2)

Radwa Ayman, Moustafa S. Abusaif, A.M. Radwan, Amira M. Elmetwally & Ahmed Ragab. (2023) Development of novel pyrazole, imidazo[1,2-b]pyrazole, and pyrazolo[1,5-a]pyrimidine derivatives as a new class of COX-2 inhibitors with immunomodulatory potential. European Journal of Medicinal Chemistry 249, pages 115138.
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Derya Osmaniye, Begüm Nurpelin Sağlık, Narmin Khalilova, Serkan Levent, Gizem Bayazıt, Ülküye Dudu Gül, Yusuf Özkay & Zafer Asım Kaplancıklı. (2023) Design, Synthesis, and Biological Evaluation Studies of Novel Naphthalene-Chalcone Hybrids As Antimicrobial, Anticandidal, Anticancer, and VEGFR-2 Inhibitors. ACS Omega 8:7, pages 6669-6678.
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