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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 38, 2023 - Issue 1
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Brief Report

Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers

I. Caroline Vaalanda Department of Chemistry, Bioscience and Environmental Engineering, Faculty of Science and Technology, University of Stavanger, Stavanger, NorwayView further author information
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Óscar Lópezb Departamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Seville, SpainCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-2896-6993View further author information
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Adrián Puertac BioLab, Instituto Universitario de Bio-Orgánica “Antonio González” (IUBO-AG), Universidad de La Laguna, c/Astrofísico Francisco Sánchez, La Laguna, SpainORCID Iconhttps://orcid.org/0000-0002-7975-1960View further author information
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Miguel X. Fernandesc BioLab, Instituto Universitario de Bio-Orgánica “Antonio González” (IUBO-AG), Universidad de La Laguna, c/Astrofísico Francisco Sánchez, La Laguna, SpainORCID Iconhttps://orcid.org/0000-0002-1840-616XView further author information
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José M. Padrónc BioLab, Instituto Universitario de Bio-Orgánica “Antonio González” (IUBO-AG), Universidad de La Laguna, c/Astrofísico Francisco Sánchez, La Laguna, SpainCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-6268-6552View further author information
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José G. Fernández-Bolañosb Departamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Seville, SpainORCID Iconhttps://orcid.org/0000-0003-1499-0650View further author information
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Magne O. Sydnesa Department of Chemistry, Bioscience and Environmental Engineering, Faculty of Science and Technology, University of Stavanger, Stavanger, NorwayORCID Iconhttps://orcid.org/0000-0001-9413-6969View further author information
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Emil Lindbäcka Department of Chemistry, Bioscience and Environmental Engineering, Faculty of Science and Technology, University of Stavanger, Stavanger, NorwayCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-5809-7368View further author information
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Pages 349-360 | Received 27 Sep 2022, Accepted 18 Nov 2022, Published online: 01 Dec 2022

Citations (4)

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Hongtao Du, Jinzhi Song, Fang Ma, Hongxin Gao, Xinyan Zhao, Renjun Mao, Xiaolong He & Yan Yan. (2023) Novel harmine derivatives as potent acetylcholinesterase and amyloid beta aggregation dual inhibitors for management of Alzheimer’s disease. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Articles from other publishers (3)

I. Caroline Vaaland Holmgard, Aday González-Bakker, Eleonora Poeta, Adrián Puerta, Miguel X. Fernandes, Barbara Monti, José G. Fernández-Bolaños, José M. Padrón, Óscar López & Emil Lindbäck. (2024) Coumarin–azasugar–benzyl conjugates as non-neurotoxic dual inhibitors of butyrylcholinesterase and cancer cell growth. Organic & Biomolecular Chemistry 22:17, pages 3425-3438.
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Yanwen Zhu, Dandan Shi, Ao Chen, Yanqun Wang, Ling Liu & Bing Bai. (2023) Mechanism of active acetylcholinesterase inhibition by organic sulfanes in garlic: Non-covalent binding and covalent modifications. International Journal of Biological Macromolecules 245, pages 124972.
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Jonathan Godinez, Catherine Y. Lee & Jason P. Schwans. (2023) Synthesis and evaluation of Fmoc-amino esters and amides bearing a substrate like quaternary ammonium group as selective butyrylcholinesterase inhibitors. Bioorganic & Medicinal Chemistry Letters 92, pages 129392.
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